Protein Alignment MetRS and mars1

DIOPT Version :10

• Sequence 1: NP_611382.1
• Gene: MetRS / 37177
• FlyBaseID: FBgn0034401
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: XP_068077760.1
• Gene: mars1 / 338183
• ZFINID: ZDB-GENE-030219-83
• Length: 942
• Species: Danio rerio
• Alignment Length: 924
• Identity: 434/924 - (46%)
• Similarity: 598/924 - (64%)
• Gaps: 73/924 - (7%)

  Fly     1 MIIYTNDGNPLGLQLLMLAKFAKQPVQVQLVNLND--AKYKDLLVLPTLELDNGLRLFSPAAIAK 63
            |.::..:|||..|::|...:.:....:.|||...:  ..|....|||.|:|.:|..||||.:|.:
Zfish    30 MKLFIGEGNPHCLKVLAALELSGVRCETQLVKHEEKVVPYLTHPVLPILQLPSGQHLFSPNSICQ 94

  Fly    64 YLFVGKGQQ----RDEWLEWSATLLAPALAHHMAV----GHKADANAL--PVLNALVKKLDDKLK 118
            |||...||:    .::||||.||.|.||:...:.:    |.:.:|.|:  ..|:.|.:.| .|.|
Zfish    95 YLFDISGQKATDATNQWLEWEATNLQPAVLQSLQLVALQGKRVEAAAVMKEPLSWLEQSL-SKRK 158

  Fly   119 ATPYLAGDKPSAADIAIWSLLAP---DGTLKGAQNVDNLRDWYGRVKALPEVQEVLAEQPLKDLS 180
            |: :|..:..|.||:.:|:.|.|   |...:.. ::..:|.|:.||.::...|.. |.:.|:...
Zfish   159 AS-FLTDEVVSVADVVLWAALYPLLSDSAFEPG-DLQAVRGWFERVCSVSACQSA-ALRVLQGKG 220

  Fly   181 FNALQQSNRYGGLHHVPLKRLSLADASKLLVDTTPTVADT---VTNEEISAAKAAFT-----YTA 237
            ..||:...:...:.|.| :|.|.:::::        ..|:   ::.|||..|...::     :|.
Zfish   221 AEALKSFLQKQPVTHTP-RRDSPSNSTE--------AEDSERELSPEEIEEAAQVYSEGLKDFTV 276

  Fly   238 PKEIKEERTVLPKPGERNVLITSALPYVNNVPHLGNIIGCVLSADIYARYSRSAGYNTLLICGTD 302
            ..|.|  ..|||:.|:|||||||||||||||||||||||||||||::|||.|..|:|.|.|||||
Zfish   277 VTERK--HPVLPQEGKRNVLITSALPYVNNVPHLGNIIGCVLSADVFARYGRLRGWNLLYICGTD 339

  Fly   303 EYGTATENKALAENLTPREICDKYFELHNAIYRWFGIGFDYFGRTTTQEQTDIVQEAFKDVLKAG 367
            ||||||||||..|.|||::|||||..:|.:||:||.|.||:|||||||.||:|.|:.|..:.:.|
Zfish   340 EYGTATENKAREEGLTPQQICDKYHCIHASIYQWFQIDFDFFGRTTTQHQTEIAQDIFWRLHERG 404

  Fly   368 YIITESVEQLLCQKCDRFLADRFVEGTCPHPGCGYEDARGDQCDKCGKLVNATELIRPRCKVCNS 432
            :::.::||||.|:.|.||||||||||.|||  |.|.:||||||||||:|:||.||..|:||||..
Zfish   405 FLLEDTVEQLRCEGCQRFLADRFVEGECPH--CRYPEARGDQCDKCGRLINAVELKNPQCKVCKE 467

  Fly   433 APVLRSSDQLFIDLPKAEPQLKEWVDKS--EGGWTHNAKVITRAWLKEGLKPRCITRDLKWGIPV 495
            .||:|||..||::|||.|..|::|:..|  .|.||.||:.|||:||::||||||||||||||.||
Zfish   468 TPVIRSSKHLFLNLPKLEQDLEQWLQTSTAAGDWTTNARHITRSWLRDGLKPRCITRDLKWGTPV 532

  Fly   496 PHEGFEKKVFYVWFDAPFGYVSMTKRYTKEYQQWWQPAKGTDVELFQFMAKDNVPFHSVVWPSVL 560
            ||..:::||||||||||.||:|:|..||.::::||:..:  .|||:.|||||||||||||:|..|
Zfish   533 PHPDYKEKVFYVWFDAPIGYLSITANYTDQWERWWKNPQ--QVELYNFMAKDNVPFHSVVFPCSL 595

  Fly   561 LAINKGHTLVSHIMATEYLNYEDGKFSKSRGIGVFGNDAQETGIPADVWRFYLASARPEGQDSSF 625
            |.....:|||::::|||||||||.|||||||:||||:.|::||||:|||||||...|||||||:|
Zfish   596 LGAQDNYTLVNNLIATEYLNYEDTKFSKSRGVGVFGDMAKDTGIPSDVWRFYLLYLRPEGQDSAF 660

  Fly   626 SWNDLAARNNSELLNNLGNFVNRALVFCEKNFSSTVPGVITTQDELVLLALINRELRGYINSMEK 690
            ||.|:|.:||||||||||||:|||.:|..|.|...||.::...|:..|:|.:..||:.||..::|
Zfish   661 SWTDMALKNNSELLNNLGNFINRAGMFVSKFFDGCVPEMLLNDDDKRLIAQVCWELKQYIQLLDK 725

  Fly   691 AKLRDGVRHLLAISRHGNGYMQSQQPWVLLKGTDDQKTRASTIIGLCVNIACLLANLLFPYMPTT 755
            .::||.::.:|.:|||||.|:|..:||..:||..:.:.||.|:.|:.||:|||||.:|.|:|||.
Zfish   726 VRIRDALKCILNMSRHGNQYIQLNEPWKKIKGGAEDRCRAGTVTGVSVNVACLLAAVLEPFMPTV 790

  Fly   756 ARTLFGQLNAKQTPLNAEKPLVT------LLLPAGHQIGKPAPLFAKLEQSFIDELKGKYGGAQA 814
            :.::..||   |.|.::.:.:::      ..|||||:||..:|||.|||...|:.|:.::||.|.
Zfish   791 SLSIRSQL---QAPESSSRAMLSGPGAFICTLPAGHRIGTVSPLFQKLENEQIEALRKRFGGLQT 852

  Fly   815 TND-------------AAHSQIS-AADLEKA------VQAQADKVRELKASTKDKAIWQPEVTKL 859
            .::             |.|:..| .||.|:|      |..|.:|||.|||...:|:....||.||
Zfish   853 PSNSSVAVESKPNAGAAQHTPASVTADPERAKQLTALVAEQGEKVRALKAQKAEKSAIGVEVAKL 917

  Fly   860 LDLKKQLEEAKKKT 873
            ||||.||..|:.||
Zfish   918 LDLKNQLCLAEGKT 931

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GST_N_5	1..70	CDD:436537	24/70 (34%)
		GST_C_family	63..164	CDD:470672	35/113 (31%)
		PLN02610	248..>850	CDD:215329	346/629 (55%)
		MetRS_RNA	895..938	CDD:238475
		MetRS_RNA	966..1009	CDD:238475
mars1	XP_068077760.1	GST_N_5	30..101	CDD:436537	24/70 (34%)
		GST_C_MetRS_N	104..205	CDD:198340	30/103 (29%)
		PLN02610	279..917	CDD:215329	352/646 (54%)