Protein Alignment: MetRS and mars

• Sequence 1: NP_611382.1
• Gene: MetRS
• FlyBaseID: FBgn0034401
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: NP_956370.1
• Gene: mars
• ZFINID: ZDB-GENE-030219-83
• Length: 922
• Species: Danio rerio
• Alignment Length: 933
• Identity: 431/934 (46%)
• Similarity: 596/934 (64%)
• Gaps: 82/934 (9%)

  Fly     1 MIIYTNDGNPLGLQLLMLAKFAKQPVQVQLVNLND--AKYKDLLVLPTLELDNGLRLFSPAAIAK 63
            |.::..:|||..|::|...:.:....:.|||...:  ..|....|||.|:|.:|..||||.:|.:
Zfish     1 MKLFIGEGNPHCLKVLAALELSGVRCETQLVKHEEKVVPYLTHPVLPILQLPSGQHLFSPNSICQ 65

  Fly    64 YLFVGKGQQ----RDEWLEWSATLLAPALAHHMAV----GHKADANALPVLNALVKKLDDKL--K 118
            |||...||:    .::||||.||.|.||:...:.:    |.:.:|.|  |:...:..|:..|  :
Zfish    66 YLFDVSGQKATDATNQWLEWEATNLQPAVLQSLQLVALQGKRVEAAA--VMKEPLSWLEQSLSKR 128

  Fly   119 ATPYLAGDKPSAADIAIWSLLAP---DGTLKGAQNVDNLRDWYGRVKALPEVQEVLAEQPLKDLS 180
            .|.:|..:..|.||:.:|:.|.|   |...:.. ::..:|.|:.||.::...|.. |.:.|:...
Zfish   129 KTSFLTDEVVSVADVVLWAALYPLLSDSAFEPG-DLQAVRGWFERVCSVSACQSA-ALRVLQGKG 191

  Fly   181 FNALQQSNRYGGLHHVPLKRLSLADASKLLVDTTPTVADT---VTNEEISAAKAAFT-----YTA 237
            ..||:...:...:.|.| :|.|.:::::        ..|:   ::.|||..|...::     :|.
Zfish   192 AEALKSFLQKQPVTHTP-RRDSPSNSTE--------AEDSERELSPEEIEEAAQVYSEGLKDFTV 247

  Fly   238 PKEIKEERTVLPKPGERNVLITSALPYVNNVPHLGNIIGCVLSADIYARYSRSAGYNTLLICGTD 302
            ..|.|  ..|||:.|:|||||||||||||||||||||||||||||::|||.|..|:|.|.|||||
Zfish   248 VTERK--HPVLPQEGKRNVLITSALPYVNNVPHLGNIIGCVLSADVFARYGRLRGWNLLYICGTD 310

  Fly   303 EYGTATENKALAENLTPREICDKYFELHNAIYRWFGIGFDYFGRTTTQEQTDIVQEAFKDVLKAG 367
            ||||||||||..|.|||::|||||..:|.:||:||.|.||:|||||||.||:|.|:.|..:.:.|
Zfish   311 EYGTATENKAREEGLTPQQICDKYHCIHASIYQWFQIDFDFFGRTTTQHQTEIAQDIFWRLHERG 375

  Fly   368 YIITESVEQLLCQKCDRFLADRFVEGTCPHPGCGYEDARGDQCDKCGKLVNATELIRPRCKVCNS 432
            :::.::||||.|:.|.||||||||||.|||  |.:.:||||||||||:|:||.||..|:||||..
Zfish   376 FLLEDTVEQLRCEGCQRFLADRFVEGECPH--CRFPEARGDQCDKCGRLINAVELKNPQCKVCKE 438

  Fly   433 APVLRSSDQLFIDLPKAEPQLKEWVDKS--EGGWTHNAKVITRAWLKEGLKPRCITRDLKWGIPV 495
            .||:|||..||::|||.|..|::|:..|  .|.||.||:.|||:||::||||||||||||||.||
Zfish   439 TPVIRSSKHLFLNLPKLEQDLEQWLQTSTAAGDWTTNARHITRSWLRDGLKPRCITRDLKWGTPV 503

  Fly   496 PHEGFEKKVFYVWFDAPFGYVSMTKRYTKEYQQWWQPAKGTDVELFQFMAKDNVPFHSVVWPSVL 560
            ||..:::||||||||||.||:|:|..||.::::||:..:  .|||:.|||||||||||||:|..|
Zfish   504 PHPDYKEKVFYVWFDAPIGYLSITANYTDQWERWWKNPQ--QVELYNFMAKDNVPFHSVVFPCSL 566

  Fly   561 LAINKGHTLVSHIMATEYLNYEDGKFSKSRGIGVFGNDAQETGIPADVWRFYLASARPEGQDSSF 625
            |.....:|||::::|||||||||.|||||||:||||:.|::||||:|||||||...|||||||:|
Zfish   567 LGAQDNYTLVNNLIATEYLNYEDTKFSKSRGVGVFGDMAKDTGIPSDVWRFYLLYLRPEGQDSAF 631

  Fly   626 SWNDLAARNNSELLNNLGNFVNRALVFCEKNFSSTVPGVITTQDELVLLALINRELRGYINSMEK 690
            ||.|:|.:||||||||||||:|||.:|..|.|...||.::...|:..|:|.:..||:.||..::|
Zfish   632 SWTDMALKNNSELLNNLGNFINRAGMFVSKFFDGCVPEMLLNDDDKRLIAQVCWELKQYIQLLDK 696

  Fly   691 AKLRDGVRHLLAISRHGNGYMQSQQPWVLLKGTDDQKTRASTIIGLCVNIACLLANLLFPYMPTT 755
            .::||.::.:|.:|||||.|:|..:||..:||..:.:.||.|:.|:.||:|||||.:|.|:|||.
Zfish   697 VRIRDALKCILNMSRHGNQYIQLNEPWKKIKGGAEDRCRAGTVTGVSVNVACLLAAVLEPFMPTV 761

  Fly   756 ARTLFGQLNAKQTPLNAEKPLVT------LLLPAGHQIGKPAPLFAKLEQSFIDELKGKYGGAQA 814
            :.::..||   |.|.::.:.:::      ..|||||:||..:|||.|||...|:.|:.::||.|.
Zfish   762 SLSIRSQL---QAPESSSRAMLSGPGAFICTLPAGHRIGTVSPLFQKLENEQIEALRKRFGGLQP 823

  Fly   815 TNDAA----------------------HSQIS-AADLEKA------VQAQADKVRELKASTKDKA 850
            ..::|                      |:..| .||.|:|      |..|.:|||.|||...:|:
Zfish   824 EEESAGLKTPSNSSVAVESKPNAGAAQHTPASVTADPERAKQLTALVAEQGEKVRALKAQKAEKS 888

  Fly   851 IWQPEVTKLLDLKKQLEEAKKKT 873
            ....||.||||||.||..|:.||
Zfish   889 AIGVEVAKLLDLKNQLCLAEGKT 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GstA	1..175	CDD:223698	56/189 (30%)
		GST_N_family	1..65	CDD:238319	22/66 (33%)
		GST_C_family	63..164	CDD:295467	33/114 (29%)
		PRK12268	254..812	CDD:237029	326/566 (58%)
		MetRS_core	255..625	CDD:173907	241/372 (65%)
		Anticodon_Ia_Met	634..763	CDD:153411	59/129 (46%)
		MetRS_RNA	828..868	CDD:238475	21/46 (46%)
		MetRS_RNA	895..938	CDD:238475
		MetRS_RNA	966..1009	CDD:238475
mars	NP_956370.1	GstA	1..173	CDD:223698	53/175 (30%)
		GST_N_family	1..67	CDD:238319	22/66 (33%)
		GST_C_MetRS_N	75..176	CDD:198340	28/104 (27%)
		PRK12268	261..820	CDD:237029	325/566 (57%)
		MetRS_core	263..631	CDD:173907	241/372 (65%)
		Anticodon_Ia_Met	640..769	CDD:153411	59/129 (46%)
		MetRS_RNA	866..910	CDD:238475	20/44 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C333217323
eggNOG	1	0.900				E1_COG0143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000				H90878
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D279987at33208
OrthoFinder	1	1.000				FOG0004323
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900				OOG5_127626
Panther	1	1.100			LDO	PTHR45765
Phylome	1	0.910		0.667	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
ZFIN	0	0.000	Not matched by this tool.
	10	9.720