Protein Alignment: MetRS and rar1

• Sequence 1: NP_611382.1
• Gene: MetRS
• FlyBaseID: FBgn0034401
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: NP_595586.1
• Gene: rar1
• PomBaseID: SPBC17A3.04c
• Length: 782
• Species: Schizosaccharomyces pombe
• Alignment Length: 803
• Identity: 332/804 (41%)
• Similarity: 457/804 (57%)
• Gaps: 110/804 (14%)

  Fly    51 NGLRLFSPAAIAKYL--------FVGKGQQRDEW----------LEWSATLLAPALAHHMAVGHK 97
            |.:||.:.....||:        |:...|:.|.:          |:|.|....|..  :.|...:
pombe    44 NSVRLVNSKEPEKYVSDANAIVSFLYWKQEEDLFNSFISSKLSILDWEALQFTPKA--YTAKTKE 106

  Fly    98 ADANALPVLNALVKKLDDKLKATPYLAGDKPSAADIAIWSLLAPDGTLKGA--QNVDNLRDWYGR 160
            ..|..|..|..:.|:.:...:.||.   :...|:||...       .|.||  :....|..||.:
pombe   107 DFAYLLSQLETIFKENEILNEFTPV---EVALASDIYFC-------VLNGAPVREYPLLSAWYLK 161

  Fly   161 V-KALPEVQEVLAEQPLKDLSFNALQQSNRYGGLHHVPLKRLSLADASKLLVDTT---PTVADTV 221
            : |..|.||                                     |.||..:.|   |.|..|
pombe   162 IEKQKPFVQ-------------------------------------ALKLTFEKTLGQPAVTST- 188

  Fly   222 TNEEISAAKAAFTYTAPKEIKEE---RTVLPKPGERNVLITSALPYVNNVPHLGNIIGCVLSADI 283
              |:|..::......:...::|.   ..:|||..|||:||||||||||||||||||:|..||||:
pombe   189 --EKIPVSETTRNVNSQHLMRERVPGEKILPKSNERNILITSALPYVNNVPHLGNIVGSTLSADV 251

  Fly   284 YARYSRSAGYNTLLICGTDEYGTATENKALAENLTPREICDKYFELHNAIYRWFGIGFDYFGRTT 348
            :|||.|:..:|||.||||||||||||.|||.|.::|:|:||||..||..:|.||.|.||:|||||
pombe   252 FARYHRARNHNTLYICGTDEYGTATETKALEEGVSPKELCDKYHALHKEVYDWFEIDFDHFGRTT 316

  Fly   349 TQEQTDIVQEAFKDVLKAGYIITESVEQLLCQKCDRFLADRFVEGTCPHPGCGYEDARGDQCDKC 413
            |.:||.|.|..|..:....|:..:::.||.|:....:||||:||||||.  |||:||||||||.|
pombe   317 TPKQTGIAQHIFTKLYNNDYMAIDTMTQLYCEVHQGYLADRYVEGTCPK--CGYDDARGDQCDGC 379

  Fly   414 GKLVNATELIRPRCKVCNSAPVLRSSDQLFIDLPKAEPQLKEWVDKS--EGGWTHNAKVITRAWL 476
            |.|:||.|||.|:||:..:.||.|.:..:|:.|.|.:|.::.|..:|  ||.|::|.:.||.:||
pombe   380 GGLLNAFELIDPKCKLDRATPVKRETKHVFLSLDKLQPAVESWAMQSAVEGKWSNNGRSITESWL 444

  Fly   477 KEGLKPRCITRDLKWGIPVPHEGFEKKVFYVWFDAPFGYVSMTKRYTKEYQQWWQPAKGTDVELF 541
            ||||:|||||||||||.|||.|.|:.||.||||||..||:|:|..||.|:::||:..:  .|:|:
pombe   445 KEGLRPRCITRDLKWGTPVPLEEFKGKVLYVWFDATIGYISITANYTDEWEKWWRNPE--QVKLY 507

  Fly   542 QFMAKDNVPFHSVVWPSVLLAINKGHTLVSHIMATEYLNYEDGKFSKSRGIGVFGNDAQETGIPA 606
            |||.|||||||:|::||.||...:..|::.||..|:|||||.||||||||:|||||.||:.|:..
pombe   508 QFMGKDNVPFHTVIFPSSLLGTGEKWTMLHHINTTDYLNYETGKFSKSRGVGVFGNTAQDIGLSP 572

  Fly   607 DVWRFYLASARPEGQDSSFSWNDLAARNNSELLNNLGNFVNRALVFCEKNFSSTVPGVITTQDEL 671
            .|||:||.|:|||..|:.|:|.:...|:|||||.||||||||.|.|....::..||..:|  |..
pombe   573 SVWRYYLLSSRPETSDTMFTWKEFITRHNSELLANLGNFVNRTLKFTTAKYNGLVPHYLT--DPS 635

  Fly   672 V--------LLALINRELRGYINSMEKAKLRDGVRHLLAISRHGNGYMQSQQPWVLLKGTDD--- 725
            |        .:..:|..|..|..::|.:|||:|:|..:.||..||.|:|..:       .|:
pombe   636 VGAGKLKADFVKDVNALLAKYNAALEASKLREGLRLAMEISARGNQYLQDNR-------IDNKCY 693

  Fly   726 --QKTRASTIIGLCVNIACLLANLLFPYMPTTARTLFGQLNAKQTPLNAEKPLVTLLLPAGHQIG 788
              ::.:.:..||..:|:..|||.:.:||||:|:.:::.||||   |..|......|.|..||:||
pombe   694 LYERQKCADAIGYALNLIYLLAAIFYPYMPSTSTSIYKQLNA---PAAAIPDTWELCLLPGHRIG 755

  Fly   789 KPAPLFAKLEQSFIDELKGKYGG 811
            :|..||.::::|..:|.:.||||
pombe   756 EPEYLFTRIDESMEEEWRSKYGG 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GstA	1..175	CDD:223698	32/145 (22%)
		GST_N_family	1..65	CDD:238319	5/14 (36%)
		GST_C_family	63..164	CDD:295467	26/122 (21%)
		PRK12268	254..812	CDD:237029	286/574 (50%)
		MetRS_core	255..625	CDD:173907	214/372 (58%)
		Anticodon_Ia_Met	634..763	CDD:153411	48/142 (34%)
		MetRS_RNA	828..868	CDD:238475
		MetRS_RNA	895..938	CDD:238475
		MetRS_RNA	966..1009	CDD:238475
rar1	NP_595586.1	PRK12268	222..779	CDD:237029	286/574 (50%)
		MetRS_core	223..591	CDD:173907	214/372 (58%)
		Anticodon_Ia_Met	600..733	CDD:153411	48/142 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	1	1.000
Homologene	1	1.000				H90878
Inparanoid	1	1.050	586	1.000	Inparanoid score	I163
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0004323
OrthoInspector	1	1.000				T1124272
orthoMCL	1	0.900				OOG5_127626
Panther	1	1.100			LDO	PTHR45765
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1449
TreeFam	1	0.960
	10	9.950