Protein Alignment MetRS and rar1

DIOPT Version :10

• Sequence 1: NP_611382.1
• Gene: MetRS / 37177
• FlyBaseID: FBgn0034401
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: NP_595586.1
• Gene: rar1 / 2540052
• PomBaseID: SPBC17A3.04C
• Length: 782
• Species: Schizosaccharomyces pombe
• Alignment Length: 803
• Identity: 332/803 - (41%)
• Similarity: 457/803 - (56%)
• Gaps: 110/803 - (13%)

  Fly    51 NGLRLFSPAAIAKYL--------FVGKGQQRDEW----------LEWSATLLAPALAHHMAVGHK 97
            |.:||.:.....||:        |:...|:.|.:          |:|.|....|..  :.|...:
pombe    44 NSVRLVNSKEPEKYVSDANAIVSFLYWKQEEDLFNSFISSKLSILDWEALQFTPKA--YTAKTKE 106

  Fly    98 ADANALPVLNALVKKLDDKLKATPYLAGDKPSAADIAIWSLLAPDGTLKGA--QNVDNLRDWYGR 160
            ..|..|..|..:.|:.:...:.||.   :...|:||...       .|.||  :....|..||.:
pombe   107 DFAYLLSQLETIFKENEILNEFTPV---EVALASDIYFC-------VLNGAPVREYPLLSAWYLK 161

  Fly   161 V-KALPEVQEVLAEQPLKDLSFNALQQSNRYGGLHHVPLKRLSLADASKLLVDTT---PTVADTV 221
            : |..|.||                                     |.||..:.|   |.|..|
pombe   162 IEKQKPFVQ-------------------------------------ALKLTFEKTLGQPAVTST- 188

  Fly   222 TNEEISAAKAAFTYTAPKEIKEE---RTVLPKPGERNVLITSALPYVNNVPHLGNIIGCVLSADI 283
              |:|..::......:...::|.   ..:|||..|||:||||||||||||||||||:|..||||:
pombe   189 --EKIPVSETTRNVNSQHLMRERVPGEKILPKSNERNILITSALPYVNNVPHLGNIVGSTLSADV 251

  Fly   284 YARYSRSAGYNTLLICGTDEYGTATENKALAENLTPREICDKYFELHNAIYRWFGIGFDYFGRTT 348
            :|||.|:..:|||.||||||||||||.|||.|.::|:|:||||..||..:|.||.|.||:|||||
pombe   252 FARYHRARNHNTLYICGTDEYGTATETKALEEGVSPKELCDKYHALHKEVYDWFEIDFDHFGRTT 316

  Fly   349 TQEQTDIVQEAFKDVLKAGYIITESVEQLLCQKCDRFLADRFVEGTCPHPGCGYEDARGDQCDKC 413
            |.:||.|.|..|..:....|:..:::.||.|:....:||||:||||||.  |||:||||||||.|
pombe   317 TPKQTGIAQHIFTKLYNNDYMAIDTMTQLYCEVHQGYLADRYVEGTCPK--CGYDDARGDQCDGC 379

  Fly   414 GKLVNATELIRPRCKVCNSAPVLRSSDQLFIDLPKAEPQLKEWVDKS--EGGWTHNAKVITRAWL 476
            |.|:||.|||.|:||:..:.||.|.:..:|:.|.|.:|.::.|..:|  ||.|::|.:.||.:||
pombe   380 GGLLNAFELIDPKCKLDRATPVKRETKHVFLSLDKLQPAVESWAMQSAVEGKWSNNGRSITESWL 444

  Fly   477 KEGLKPRCITRDLKWGIPVPHEGFEKKVFYVWFDAPFGYVSMTKRYTKEYQQWWQPAKGTDVELF 541
            ||||:|||||||||||.|||.|.|:.||.||||||..||:|:|..||.|:::||:..:  .|:|:
pombe   445 KEGLRPRCITRDLKWGTPVPLEEFKGKVLYVWFDATIGYISITANYTDEWEKWWRNPE--QVKLY 507

  Fly   542 QFMAKDNVPFHSVVWPSVLLAINKGHTLVSHIMATEYLNYEDGKFSKSRGIGVFGNDAQETGIPA 606
            |||.|||||||:|::||.||...:..|::.||..|:|||||.||||||||:|||||.||:.|:..
pombe   508 QFMGKDNVPFHTVIFPSSLLGTGEKWTMLHHINTTDYLNYETGKFSKSRGVGVFGNTAQDIGLSP 572

  Fly   607 DVWRFYLASARPEGQDSSFSWNDLAARNNSELLNNLGNFVNRALVFCEKNFSSTVPGVITTQDEL 671
            .|||:||.|:|||..|:.|:|.:...|:|||||.||||||||.|.|....::..||..:|  |..
pombe   573 SVWRYYLLSSRPETSDTMFTWKEFITRHNSELLANLGNFVNRTLKFTTAKYNGLVPHYLT--DPS 635

  Fly   672 V--------LLALINRELRGYINSMEKAKLRDGVRHLLAISRHGNGYMQSQQPWVLLKGTDD--- 725
            |        .:..:|..|..|..::|.:|||:|:|..:.||..||.|:|..:       .|:
pombe   636 VGAGKLKADFVKDVNALLAKYNAALEASKLREGLRLAMEISARGNQYLQDNR-------IDNKCY 693

  Fly   726 --QKTRASTIIGLCVNIACLLANLLFPYMPTTARTLFGQLNAKQTPLNAEKPLVTLLLPAGHQIG 788
              ::.:.:..||..:|:..|||.:.:||||:|:.:::.||||   |..|......|.|..||:||
pombe   694 LYERQKCADAIGYALNLIYLLAAIFYPYMPSTSTSIYKQLNA---PAAAIPDTWELCLLPGHRIG 755

  Fly   789 KPAPLFAKLEQSFIDELKGKYGG 811
            :|..||.::::|..:|.:.||||
pombe   756 EPEYLFTRIDESMEEEWRSKYGG 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GST_N_5	1..70	CDD:436537	6/26 (23%)
		GST_C_family	63..164	CDD:470672	26/121 (21%)
		PLN02610	248..>850	CDD:215329	290/579 (50%)
		MetRS_RNA	895..938	CDD:238475
		MetRS_RNA	966..1009	CDD:238475
rar1	NP_595586.1	PLN02610	216..>779	CDD:215329	290/579 (50%)