Protein Alignment: MetRS and mars-1

• Sequence 1: NP_611382.1
• Gene: MetRS
• FlyBaseID: FBgn0034401
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: NP_001255570.1
• Gene: mars-1
• WormBaseID: WBGene00003415
• Length: 917
• Species: Caenorhabditis elegans
• Alignment Length: 795
• Identity: 353/796 (44%)
• Similarity: 485/796 (61%)
• Gaps: 66/796 (8%)

  Fly   225 EISAAKAAFTYTAP--KEIKEERTVLPKPGERNVLITSALPYVNNVPHLGNIIGCVLSADIYARY 287
            :::..|.:|..:.|  .|.|:.:::||:||:||:|||:||||||||||||||||||||||::|||
 Worm     4 DLADIKKSFEASLPGYVEKKDPKSILPQPGKRNILITAALPYVNNVPHLGNIIGCVLSADVFARY 68

  Fly   288 SRSAGYNTLLICGTDEYGTATENKALAENLTPREICDKYFELHNAIYRWFGIGFDYFGRTTTQEQ 352
            ....|:.|..:.||||||||||.|||.|..||||:||||..:|..||.||||.|.:||||||..|
 Worm    69 CNLRGHQTFYVGGTDEYGTATETKALQEGCTPRELCDKYHAIHKGIYEWFGIDFSHFGRTTTDHQ 133

  Fly   353 TDIVQEAFKDVLKAGYIITESVEQLLCQKCDRFLADRFVEGTCPHPGCGYEDARGDQCDKCGKLV 417
            |:|.|:.|..:.|.||..::||:||.|.:|::|||||||.||||.  |.|:||||||||.||||:
 Worm   134 TEICQDMFLKLHKNGYTSSQSVDQLYCNQCEKFLADRFVTGTCPM--CAYDDARGDQCDGCGKLI 196

  Fly   418 NATELIRPRCKVCNSAPVLRSSDQLFIDLPKAEPQLKEWVD----KSEGGWTHNAKVITRAWLKE 478
            ||.:|...:|.:|.:.|.::.|..:|:.|.|.:.:..|.:|    |.:..|:.||..||:||:|.
 Worm   197 NAVDLKDAKCHMCKATPEVKQSTHIFLSLDKLQQKTTEHLDRELAKEDNRWSSNAVGITKAWMKL 261

  Fly   479 GLKPRCITRDLKWGIPVPHEGFEKKVFYVWFDAPFGYVSMTK-----RYTKEYQQWWQPAKGTDV 538
            ||.|||||||||||..||.:||||||||||||||.||:|:||     .:||    ||:..:  :|
 Worm   262 GLDPRCITRDLKWGTAVPLDGFEKKVFYVWFDAPIGYLSITKCVLGDNWTK----WWKNPE--NV 320

  Fly   539 ELFQFMAKDNVPFHSVVWPSVLLAINKGHTLVSHIMATEYLNYEDGKFSKSRGIGVFGNDAQETG 603
            |||.|:.||||.||:|::|...|..|..:|:|:::.|||||||||.|||||||.|:||:.||.|.
 Worm   321 ELFNFVGKDNVAFHAVMFPCSQLGANDNYTVVNNLCATEYLNYEDTKFSKSRGTGIFGDAAQGTE 385

  Fly   604 IPADVWRFYLASARPEGQDSSFSWNDLAARNNSELLNNLGNFVNRALVFCEKNFSSTVPGVITTQ 668
            ||||:|||||...|||.||::|||:|...:.|||||||||||:||||.|...:|...||.:..|.
 Worm   386 IPADIWRFYLLYMRPESQDTAFSWDDFVLKVNSELLNNLGNFINRALSFVANSFGGVVPEMNLTN 450

  Fly   669 DELVLLALINRELRGYINSMEKAKLRDGVRHLLAISRHGNGYMQSQQPWVLLKGTDDQKTRASTI 733
            |:..:|:.|:.|...:....:...|:|.|:.:|.:||.||.|||:|.||||:|..::.|.||.||
 Worm   451 DDAEVLSEIHNECMQWDKQFDGVHLKDAVKTILNVSRLGNQYMQAQTPWVLMKKDEEGKKRAGTI 515

  Fly   734 IGLCVNIACLLANLLFPYMPTTARTLFGQLNAKQTPLNAEKPLVTLLLPAGHQIGKPAPLFAKLE 798
            ||:..|||..::.||:|.|||.:.|:..|......||....|:  ..|.|||:||:|:|||.||:
 Worm   516 IGVAANIAYHVSVLLYPIMPTISATIREQCGLPALPLFTPFPI--CYLKAGHKIGQPSPLFQKLD 578

  Fly   799 QSFIDELKGKYGGAQATNDAAHSQISAADLEKAVQAQADKVRELK--ASTKDKAIWQPEVTKLLD 861
            .:.|.|.|.|:||:|             |.:.:....|:|.::.|  |.||||
 Worm   579 PAQIAEFKAKFGGSQ-------------DAQSSAPKTAEKPKQQKKQAPTKDK------------ 618

  Fly   862 LKKQLEEAKKKTATAAAPAATPAPSNGSQSV-QDLEKAIQEQG----DKVRKLKGSTKDKTVWQP 921
                 :..||..:|||...........||.: |:|:|..|.:.    :::::|.|..|..|:
 Worm   619 -----KGDKKMASTAAFVELEQGAKVISQLIAQNLKKFDQAKALFTRNQLQRLDGENKQLTI--- 675

  Fly   922 EVNILLDLKKQLE---AVQKAAKAAPAANAAPAASPAA--TADAAKVKALEDKIAQQAEKVRTLK 981
            :|..|.....:||   .:::..|...:....|.::||:  ..:|.|.:|.......:.:|.:..|
 Worm   676 DVKTLQHQLIELETAAGIKQVPKPVVSCTPTPTSTPASGIITEAPKKEAPSTPAPSEPKKAKEQK 740

  Fly   982 ATGDAAVWKPEVDIL 996
            .....|...|..|.:
 Worm   741 KGKGGAAAAPVDDTI 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GstA	1..175	CDD:223698
		GST_N_family	1..65	CDD:238319
		GST_C_family	63..164	CDD:295467
		PRK12268	254..812	CDD:237029	303/567 (53%)
		MetRS_core	255..625	CDD:173907	218/379 (58%)
		Anticodon_Ia_Met	634..763	CDD:153411	59/129 (46%)
		MetRS_RNA	828..868	CDD:238475	8/42 (19%)
		MetRS_RNA	895..938	CDD:238475	11/50 (22%)
		MetRS_RNA	966..1009	CDD:238475	5/32 (16%)
mars-1	NP_001255570.1	PLN02610	21..898	CDD:215329	350/779 (45%)
		MetRS_core	36..407	CDD:173907	218/379 (58%)
		Anticodon_Ia_Met	416..544	CDD:153411	58/128 (45%)
		tRNA_bind_EMAP-II_like	755..857	CDD:239198	0/2 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C333222774
eggNOG	1	0.900				E1_COG0143
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	641	1.000	Inparanoid score	I440
Isobase	1	0.950		0	Normalized mean entropy	S822
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D279987at33208
OrthoFinder	1	1.000				FOG0004323
OrthoInspector	1	1.000				T476987
orthoMCL	1	0.900				OOG5_127626
Panther	1	1.100			LDO	PTHR45765
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1449
TreeFam	1	0.960
	13	12.740