Protein Alignment MetRS and MetRS-m

DIOPT Version :10

• Sequence 1: NP_611382.1
• Gene: MetRS / 37177
• FlyBaseID: FBgn0034401
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: XP_312573.5
• Gene: MetRS-m / 1273580
• VectorBaseID: AGAMI1_002951
• Length: 563
• Species: Anopheles gambiae
• Alignment Length: 641
• Identity: 150/641 - (23%)
• Similarity: 247/641 - (38%)
• Gaps: 150/641 - (23%)

  Fly   258 ITSALPYVNNVPHLGNIIGCVLSADIYARYSR----SAGYNTLLICGTDEYGTATENKALAENLT 318
            :|:.:.|||..||:|::...|: ||...|:::    :...|..|..||||:|...:..|:..:.:
Mosquito    20 VTTPIFYVNAAPHIGHLYSSVI-ADAIHRFNQITCPAESGNCFLSTGTDEHGLKIQQAAIKHSTS 83

  Fly   319 PREICDKYFELHNAIYRWFGIGFDYFGRTTTQEQTDIVQEAFKDVLKAGYIITESVEQLLCQKCD 383
            ..:.||.....:..::..|.|.:..|.|||..:....||..::.:..:..|.:.|.....|...:
Mosquito    84 TEDYCDAISTKYRELFGRFQIDYSRFIRTTDTDHRQAVQSFWRSLAASDSIYSASYSGWYCVPDE 148

  Fly   384 RFLADRFVEGTCPHPGCGYEDARGDQCD-KCGKLVNATELIRPRCKVCNSAPVLRSSDQLFIDLP 447
            .||.|..::          |:.||::|. :.|..|..||                 .:.....|.
Mosquito   149 TFLTDSQLK----------ENERGEKCSLESGHPVEWTE-----------------EENYMFRLS 186

  Fly   448 KAEPQLKEWVDKSEGGWTHNAKV--ITRAWLKEGLKPRCITRDL---KWGIPVPHEGFEKKVFYV 507
            :.:..::.||...||......|.  |...||:|.|....|:|.:   .||:|||.:  ..:..||
Mosquito   187 RYQDDVRHWVKGLEGRRIQPDKFGRILLDWLEEPLPDISISRPMNRVSWGVPVPSD--PSQSVYV 249

  Fly   508 WFDAPFGYVSMTKRYTKE-YQQWWQPAKGTDVELFQFMAKDNVPFHSVVWPSVLLA--INKGHTL 569
            |.||...|:::. .|.|| ::..|.|.       .|.:.||.:.||.:.||:.|||  |.....|
Mosquito   250 WLDALVNYLTVA-GYPKESFRTRWPPT-------VQVLGKDILKFHGIYWPAFLLAAQIEPPRQL 306

  Fly   570 VSHIMATEYLNYEDGKFSKSRGIGVFGNDAQE----TGIPADVWRFYLASARPEGQDSSFSWNDL 630
            :.|    .:...::.|.|||:...|..|:..|    .|:     |::|........|.::|...:
Mosquito   307 LVH----SHWTVDNQKMSKSKQNVVDPNERAELYTYEGL-----RYFLLREGVAHSDGNYSDTKV 362

  Fly   631 AARNNSELLNNLGNFVNRALVFCEK--NFSSTVPGVITTQDELVLLALINRELRGYINSMEKAK- 692
            ....||||.:.|||.::|.   |.|  |..|..|.|             :||..|.:..::..|
Mosquito   363 LRILNSELADTLGNLLSRC---CGKALNAESIFPAV-------------DREALGALKEIDATKR 411

  Fly   693 -----------------------LRDGVRHLLAISRHGNGYMQSQQPWVLLKGTDDQKTRA--ST 732
                                   :.|.:.|||   ...|.:.::..|| .||.:|:...||  :|
Mosquito   412 MLEALEEMPDKASSHYKNYNFYLVVDTIVHLL---HTANNFFETTAPW-KLKKSDNPADRAKLNT 472

  Fly   733 IIGLCVNIACLLANLLFPYMPTTARTLFGQLNAKQTPLNAEKPLVTLLLPAGHQIGKPAPLFAKL 797
            |:.:.:.:.........|.:|..::.|..:|                      ||...|..:..|
Mosquito   473 ILSVTMEVLRQAGIAAQPIVPGLSKQLLDKL----------------------QIVPTARRWNNL 515

  Fly   798 EQSFIDELKGKYGGAQATNDAAHSQ----ISAADLEKAVQAQADKVRELKASTKDK 849
            :.||            .|.||..:|    :....:..|.:...|::|..|..||.|
Mosquito   516 QVSF------------RTQDAPLAQDECILFRRIMPPAQKTDPDQIRSEKRPTKKK 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GST_N_5	1..70	CDD:436537
		GST_C_family	63..164	CDD:470672
		PLN02610	248..>850	CDD:215329	150/641 (23%)
		MetRS_RNA	895..938	CDD:238475
		MetRS_RNA	966..1009	CDD:238475
MetRS-m	XP_312573.5	None