Protein Alignment MetRS and Mars2

DIOPT Version :10

• Sequence 1: NP_611382.1
• Gene: MetRS / 37177
• FlyBaseID: FBgn0034401
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: XP_003750747.1
• Gene: Mars2 / 100911305
• RGDID: 1311527
• Length: 586
• Species: Rattus norvegicus
• Alignment Length: 604
• Identity: 147/604 - (24%)
• Similarity: 234/604 - (38%)
• Gaps: 118/604 - (19%)

  Fly   253 ERNVLITSALPYVNNVPHLGNIIGCVLSADIYARYSR----SAGYNTLLICGTDEYGTATENKAL 313
            |.....|:.:.|||..||:|::...:| ||...|:.|    .:| :|....||||:|...:..|.
  Rat    35 EARAYFTTPIFYVNAAPHIGHLYSALL-ADALCRHRRLRVPGSG-STRFSTGTDEHGLKIQQAAA 97

  Fly   314 AENLTPREICDKYFELHNAIYRWFGIGFDYFGRTTTQEQTDIVQEAFKDVLKAGYIITESV-EQL 377
            ...|.|.|:||:.......::|..||....|.|||.......||. |..||:|..::.:.: |..
  Rat    98 TAGLAPIELCDRVSAQFLQLFREAGISSTDFIRTTEARHRVAVQH-FWGVLEARGLLYKGIYEGW 161

  Fly   378 LCQKCDRFLADRFVEGTCPHPGCGYEDARGDQCDKCGKLVNATELIRPRCKVC-----NSAPVLR 437
            .|...:.||.:                            ...|..:.|....|     :..||..
  Rat   162 YCASDECFLPE----------------------------AKVTRQVGPSGDPCPVSLESGHPVSW 198

  Fly   438 SSDQLFI-DLPKAEPQLKEWVDKSEGGWTHNAKVIT--------RAWLKEGLKPRCITR---DLK 490
            :.::.:| .|.:....|:.|:       .:|.:.||        ..||:|.|....::|   .|.
  Rat   199 TKEENYIFKLSQFREPLQRWL-------RNNPQAITPEPFHQVVLQWLEEELPDLSVSRRSSHLH 256

  Fly   491 WGIPVPHEGFEKKVFYVWFDAPFGYVSMTKRYTKEYQQWWQPAKGTDVELFQFMAKDNVPFHSVV 555
            ||||||  |.:.:..|||.||...|:::......:::.|| ||..      ..:.||.:.||::.
  Rat   257 WGIPVP--GDDSQTIYVWLDALVNYLTVVGYPDADFKSWW-PATS------HIIGKDILKFHAIY 312

  Fly   556 WPSVLL--AINKGHTLVSHIMATEYLNYEDGKFSKSRGIGVFGNDAQETGIPADVWRFYLASARP 618
            ||::||  .:...|.:..|    .:......|.|||.|..|......:. ...|.:|::|.....
  Rat   313 WPALLLGAGLRPPHRICVH----SHWTVSGQKMSKSLGNVVDPRTCLDR-YTVDGFRYFLLRQGV 372

  Fly   619 EGQDSSFSWNDLAARNNSELLNNLGNFVNRALV-----------FCEKNFSSTVPGV------IT 666
            ...|..:....:....:|||.:.||..:||...           ||...|.|. ||:      :.
  Rat   373 PNWDCDYYDEKVVKLLDSELADALGGLLNRCTAYRINPSGTYPSFCAACFPSE-PGLMGPSVRVQ 436

  Fly   667 TQDELVL--LALINRELRGYINSMEKAKLRDGVRHLLAISRHGNGYMQSQQPWVLLKGTDDQKTR 729
            .:|..::  :|.:.:.:.||.|..:..|..:.|...:   |..||::|...||.|...:......
  Rat   437 AEDYALVNAVATLPKLVAGYYNDFQIYKALEAVSSCV---RQTNGFVQRHAPWKLTWESPADAPW 498

  Fly   730 ASTIIGLCVNIACLLANLLFPYMPTTARTLFGQLNAKQTPLNAEKPLVTL-LLPAGHQIGKPAP- 792
            ..|::.:.:....:...||.|..|..|..|..:|....|    |:.|..| .||..:  |.|.|
  Rat   499 LGTVLHVALECLRVFGTLLQPVTPNLADKLLSRLGVSTT----ERSLGELYFLPRFY--GHPCPF 557

  Fly   793 -----------LFAKLEQS 800
                       ||.:|:||
  Rat   558 EGRKLGPDTGLLFPRLDQS 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GST_N_5	1..70	CDD:436537
		GST_C_family	63..164	CDD:470672
		PLN02610	248..>850	CDD:215329	147/604 (24%)
		MetRS_RNA	895..938	CDD:238475
		MetRS_RNA	966..1009	CDD:238475
Mars2	XP_003750747.1	MetG	37..574	CDD:439913	143/598 (24%)