Protein Alignment MetRS and mars2

DIOPT Version :10

• Sequence 1: NP_611382.1
• Gene: MetRS / 37177
• FlyBaseID: FBgn0034401
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: XP_002940449.2
• Gene: mars2 / 100488527
• XenbaseID: XB-GENE-5862162
• Length: 571
• Species: Xenopus tropicalis
• Alignment Length: 591
• Identity: 150/591 - (25%)
• Similarity: 224/591 - (37%)
• Gaps: 107/591 - (18%)

  Fly   252 GERNVLITSALPYVNNVPHLGNIIGCVLSADIYARYSRSAGYNTLLICGTDEYGTATENKALAEN 316
            |.|..|.|:.:.|||..||||::...:| ||:..|||...|..:.|..||||:|...:..|.|.:
 Frog    41 GTRPHLYTTPIFYVNASPHLGHVYSALL-ADVQHRYSAMCGIESRLSTGTDEHGMKVQQAASALS 104

  Fly   317 LTPREICDKYFELHNAIYRWFGIGFDYFGRTTTQEQTDIVQEAFKDVLKAGYIITESVEQLLCQK 381
            |.|...|.........|:....|.:..|.|||.....:.|...:..:.:.|||...:.|...|..
 Frog   105 LDPHTFCSSVSLQFRNIFDDLDISYTDFVRTTEPRHKEAVSRFWMTLEERGYIYKGTYEGWYCTS 169

  Fly   382 CDRFLADRFVEGTCPHPGCGYEDARGDQCDKCGKLVNATELIRPRCKVCNSAPVLRSSDQL---- 442
            .:.||:               |....::.|..|..:..:               |.|..|:
 Frog   170 DEAFLS---------------EGQTAERIDSEGNKIRVS---------------LESGHQVHWVS 204

  Fly   443 ----FIDLPKAEPQLKEWVDKSEGGWTHNAKV--ITRAWLKEGLKPRCITRD---LKWGIPVPHE 498
                ...|....|.|..|:....   .|.|..  :...||:|.|....::|.   |.||||||.:
 Frog   205 EENYMFRLSSLRPALLNWLQTEP---VHPAPFLRLVHHWLEEELPDLSVSRQRSRLSWGIPVPSD 266

  Fly   499 GFEKKVFYVWFDAPFGYVSMTKRYTKEYQQWWQPAKGTDVELFQFMAKDNVPFHSVVWPSVLLA- 562
              ...|.|||.||...|::.......:...|     |....|   :.||.:.||::.||:.|:|
 Frog   267 --SSHVIYVWLDALVNYLTAAGYPNLQLAPW-----GPSTHL---LGKDILRFHAIYWPAFLIAA 321

  Fly   563 -INKGHTLVSHIMATEYLNYEDGKFSKSRGIGVFGNDAQETGIPADVWRFY---------LASAR 617
             ::..|.|:.|    .:...|..|.|||         .:....|||..|.|         |....
 Frog   322 GLSPPHKLLVH----SHWTSEGTKMSKS---------LKNVVDPADCIRRYTKDGLRYYLLRHGA 373

  Fly   618 PEGQDSSFSWNDLAARNNSELLNNLGNFVNRALV--------FCEKNFSSTVPGVITTQDELVLL 674
            || :|..|:........||||.:.||..:||...        |.:.::.| .|.....|.:.||.
 Frog   374 PE-RDCDFTHRTARTLLNSELADALGGLLNRCTAPAINPMQHFPKFHYDS-FPSAAHDQLQGVLA 436

  Fly   675 ALINRELRGYINS-MEKAKLRDGVRHLLAISRHGNGYMQSQQPWVLLKGTDDQKTRASTIIGLCV 738
            .|.|  |...::. ::|.::...:..:.|..|..|.:.|||.||.|.:|.:.:.....::|.:.:
 Frog   437 NLQN--LPAEVDQWVKKFQVHKALECIDACVRRSNAFFQSQAPWKLQRGVEKEAALRDSVIYVTL 499

  Fly   739 NIACLLANLLFPYMPTTARTLFGQLNAKQTPLNAEKPLVTLLLPA---------GHQIG-KPAPL 793
            ....|.|.||.|.:|..|.....:|.   .||..........|.|         |..:| :...|
 Frog   500 ESLRLYATLLQPAVPGLATAALERLG---VPLEMRTLKGNTFLAATRGESCYFQGQTLGPEKGLL 561

  Fly   794 FAKLEQ 799
            |.:||:
 Frog   562 FPRLER 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GST_N_5	1..70	CDD:436537
		GST_C_family	63..164	CDD:470672
		PLN02610	248..>850	CDD:215329	150/591 (25%)
		MetRS_RNA	895..938	CDD:238475
		MetRS_RNA	966..1009	CDD:238475
mars2	XP_002940449.2	MetG	43..566	CDD:439913	147/586 (25%)