Protein Alignment Cyp12b2 and cyp27c1

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001106808.2
• Gene: cyp27c1 / 558396
• ZFINID: ZDB-GENE-080204-68
• Length: 540
• Species: Danio rerio
• Alignment Length: 552
• Identity: 139/552 - (25%)
• Similarity: 261/552 - (47%)
• Gaps: 79/552 - (14%)

  Fly     9 IYRNVSGNQLWFNRNSSVGGTLSQQTQLELADSRIDEKWQQARSFGEIPGPS-LLRMLSFFMPGG 72
            ::::|:...|....:|.  ..|.:::.:..|:.  .:|..:.:|..|:|||| :..:|.||...|
Zfish    30 LHKSVASGSLEIAAHSQ--ADLKEESAVSPAEE--VQKAARVKSLKEMPGPSTVANLLEFFYRDG 90

  Fly    73 ALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYR 137
            ..| .:.|||....:  ||.|:  ....|....|...:.|......|:|...|.|..:||...||
Zfish    91 FSR-IHEIQMEHAKK--YGKIF--KSRFGPQFVVSIADRDMVAQVLRSESATPQRGNMESWKEYR 150

  Fly   138 KIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPET 202
            .:.....     ||.|.:|.||..:|:.:..::|:.::|......::.:..:.:.:::|.|:.:.
Zfish   151 DLRGRST-----GLISAEGDEWLKMRSVLRQLIMRPRDVAVFSSDVNDVVADLVKRVKTLRSQQD 210

  Fly   203 HTLTT-DFHNQLKMWAFESISFVALNTRMGLLSDNPDPNADR---LAKHMRDFFNYSFQFDVQPS 263
            .:.|. :.::....:|.|.::.:...||:|.| :|..|...:   .|.|:
Zfish   211 DSQTVLNINDLFFKYAMEGVATILYETRLGCL-ENEIPKMSQEYITALHL--------------- 259

  Fly   264 IWTFYKT---AG-------------FKKFLKTYDNITDITSNYIETAMRGFGKNDDGKTKCVLEQ 312
            :::.:||   ||             :::|..::|.:...:..:::..:....|..: |::.:...
Zfish   260 MFSSFKTTMYAGAIPKWLRPIIPKPWEEFCSSWDGLFKFSQIHVDKRLSEIKKQME-KSEEIKGG 323

  Fly   313 LLEH-------NKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQEKLRRELLRIL----P 366
            ||.|       |.:.....:.:||:||:||||.......|.|||:|:.|:::..|:.|:|    |
Zfish   324 LLTHMLVTREMNLEEIYANMTEMLLAGVDTTSFTLSWSTYLLARHPTIQQQIFEEVDRVLGGRVP 388

  Fly   367 TTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQVPRGTGVLMGVLELSND 431
            |.:|      ...:|.:|..:||.||:..:.|||.|:|..||::.||.:|:||.:.:.....|.|
Zfish   389 TGED------VPYLPLIRGLVKETLRLFPVLPGNGRVTHDDLIVGGYLIPKGTQLALCHYSTSMD 447

  Fly   432 DKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRL 496
            ::.|.:..||.|:||::.|.:..:         :.|..:|||:|.|:|||:||||||:...|.:|
Zfish   448 EENFPRPEEFRPDRWIRKDASDRV---------DNFGSIPFGYGIRSCIGRRIAELEMHLALTQL 503

  Fly   497 LRSYKVSWLPETPIEYESTI-ILSPCGDIRFK 527
            |:::.:...|:|...:..|. :|.|...|..:
Zfish   504 LQNFHIEVSPQTTEVHAKTHGLLCPGASINLR 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	118/469 (25%)
cyp27c1	NP_001106808.2	cytochrome_P450	102..533	CDD:477761	118/471 (25%)