Protein Alignment: Cyp12b2 and Cyp27b1

• Sequence 1: NP_611370.2
• Gene: Cyp12b2
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_446215.1
• Gene: Cyp27b1
• RGDID: 69192
• Length: 501
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 140/491 (29%)
• Similarity: 226/491 (46%)
• Gaps: 47/491 (10%)

  Fly    51 RSFGEIPGPSLLRMLSFFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFTYNPDDFE 115
            ||..:|||||....|:.....|.|...:.:|::...|  ||.|:  .|..|....|:..:|...|
  Rat    28 RSLSDIPGPSTPSFLAELFCKGGLSRLHELQVHGAAR--YGPIW--SGSFGTLRTVYVADPALVE 88

  Fly   116 MTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLMKVQNVRQNL 180
            ...|.|...|.|....|.:.:|:.|:    :..|.|.:| |:||..:|:.:.|:|::.|......
  Rat    89 QLLRQESHCPERCSFSSWSEHRRRHQ----RACGLLTAD-GEEWQRLRSLLAPLLLRPQAAAGYA 148

  Fly   181 PQLDQISKEFIDKLETQRN-----PETHTLTTDFHNQLKMWAFESISFVALNTRMGLLSDNPDPN 240
            ..||.:..:.:.:|..||.     |:   |..|...:...:..|.|..|.|.:|:|.|.....|:
  Rat   149 GTLDSVVSDLVRRLRRQRGRGSGLPD---LVLDVAGEFYKFGLEGIGAVLLGSRLGCLEAEVPPD 210

  Fly   241 ADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAG-FKKFLKTYDNITDITSNYI-----ETAMRGFG 299
            .:...:.:...|..:......|| |......| :.:..:.:|.:......::     |.|:|..|
  Rat   211 TETFIEAVGSVFVSTLLTMAMPS-WLHRLIPGPWARLCRDWDQMFAFAQKHVEQREGEAAVRNQG 274

  Fly   300 K-NDDGKTKCVLEQLLEHNKKVAVTMVM----DMLMAGIDTTSSACLTILYHLARNPSKQEKLRR 359
            | .:|..|...|...| ..:||:|..::    ::|:||:||.|:.....||.|:|:|..|..|..
  Rat   275 KPEEDLPTGHHLTHFL-FREKVSVQSIVGNVTELLLAGVDTVSNTLSWALYELSRHPEVQSALHS 338

  Fly   360 ELL-RILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQVPRGTGVLM 423
            |:. .:.|.:...|.......:|.|:|.|||.||:..:.|||.|:..:|:.:..|.:|:.|.|.:
  Rat   339 EITGAVNPGSYAHLQATALSQLPLLKAVIKEVLRLYPVVPGNSRVPDRDICVGNYVIPQDTLVSL 403

  Fly   424 GVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAELE 488
            .....|.|...|.:.:.|.|.|||....||           :||..||||||.|:|||:|:||||
  Rat   404 CHYATSRDPAQFREPNSFNPARWLGEGPAP-----------HPFASLPFGFGKRSCIGRRLAELE 457

  Fly   489 IETLLVRLLRSYKVSWLPE---TPIEYESTIILSP 520
            ::..|.::|..::|  |||   .|::..:..:|.|
  Rat   458 LQMALAQILTHFEV--LPEPGALPVKPMTRTVLVP 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	p450	59..511	CDD:299894	133/472 (28%)
Cyp27b1	NP_446215.1	p450	34..498	CDD:278495	137/485 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	200	1.000	Inparanoid score	I3652
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000				T131183
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960