Protein Alignment Sec6 and exoc3l1

DIOPT Version :10

• Sequence 1: NP_611351.1
• Gene: Sec6 / 37142
• FlyBaseID: FBgn0266671
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_002931727.3
• Gene: exoc3l1 / 100496045
• XenbaseID: XB-GENE-6258780
• Length: 806
• Species: Xenopus tropicalis
• Alignment Length: 735
• Identity: 193/735 - (26%)
• Similarity: 369/735 - (50%)
• Gaps: 32/735 - (4%)

  Fly     3 LQQLEEQARQAALKDIQNMLQRPGQLEKVEQYRHRIARKKASVEALLKTGMQGQLDGVRVGLKQL 67
            |::.|..||.||||....:..||.||.::..||.|..::..|::..||:.:|..|:||..|:|||
 Frog    50 LEKAESLARGAALKWASGIFSRPDQLTRLGHYRRRETQRNNSIQTRLKSAVQSYLEGVEQGIKQL 114

  Fly    68 ETCMQDVREVRRRMDEVERLLRGVPEVYDALEVVREENTKHSQYATAMENLKHIFNVDASVQKTM 132
            .:.:.:|:.|:|.:.|.:.:.|........|:.:|....:|.|.:..:::|..|:.|...:..|.
 Frog   115 HSALTEVQNVQRELSEAQGIWRKTNGQLSRLQPIRNLVAEHVQLSVVIQSLPFIYTVPELISHTK 179

  Fly   133 ALIEDDKLLNAHQCLADLENSRDDLLYELHK------------QPKQHASDKITL-KRHFEKVDT 184
            .|||...||.||:.|.:||:.||.:||.|.:            :..||..|...| ::.|..|:.
 Frog   180 NLIETQNLLEAHRNLRELESFRDIVLYRLQRVRPLEDPSCCTGEDVQHGEDPAELVQQFFAGVNN 244

  Fly   185 VSQELEKKLRLILSRTLNTLRKKPTIIVTALRIIEREEKNDQFALQQQKVTGFLPPGRPKAWRRM 249
            :|::|.:.|..:...:::..|..|:::|:|:|||||||..|:...:......:.||||||.||..
 Frog   245 LSEDLGRVLFSLAQSSVSLARSNPSLLVSAVRIIEREEYLDEEDTKGSPQQLWRPPGRPKHWRDS 309

  Fly   250 IMDVLQQSVITRIEGSKLEERADNKMWLVRDLEILRQIILEDLRVVKSLCVPCFPPHYDIFGEYV 314
            ....|::.|..|:.||.|:|.......|....:.|:..:|::|:.|.|:..||.||.|::.....
 Frog   310 FFQALERGVCNRLIGSGLQEEDITPTGLATHFKDLQSKVLDELQAVCSVLAPCVPPQYEVCRAVA 374

  Fly   315 KFYHEGLSSYLDNIVRSGLEGNEYVSMMAWVTHTYPGVELMSHPDLNVDVH-RQIGTLLRPEHLK 378
            ...|..:|.::.:|:...|.......::.|....||..:::.|.||:.::. .::|.||.||.|:
 Frog   375 LMCHHAISRHVRDILSHDLAHPALYRVLHWSVIVYPSEDMIGHQDLSPEIDATELGALLSPEFLE 439

  Fly   379 ALEDEYLQNMQRNFQEWMTKAAETEKQEWFTETVPDQDEE-YYHTSAPVIIFQMIDQHLQVTNTI 442
            ..::.|.::::....:|:.||.|.|..|||.|..||:|:: .|.:|...:|.||:.:::|:.:.:
 Frog   440 EQQNRYTRSVKVCLAQWIQKALEVEYSEWFREQEPDKDQDGLYLSSLQQLIMQMLAENMQLASVL 504

  Fly   443 HQELTFK---ALVMSIQQVEIF-GQTYLKNVIELKEHHFRNRDQIKYFTHYIITIVNNSQQMVEL 503
            ...|..:   |.|:.:....:: .:..:|..||    |.::|....|:..|::.|:|.   ...|
 Frog   505 GDSLESRMRNAAVLEMDNCLVWLREALVKYGIE----HMKDRTNPTYYIPYLVAIING---CTAL 562

  Fly   504 AQQMKQLYWPKSRTEHY-EDFERLLATFQRIRAHAASYLLEEAFLDMECHFNDLFTAKWLASNIA 567
            :..:..|...:|..... ::...|..:..:.:..|...||:|...:::..|..:.:..||:.:..
 Frog   563 SSSISYLQPGESANPVIRKNAPCLQNSLDKTQKKACHLLLDELQTELQPLFLQIPSRTWLSGSDI 627

  Fly   568 VDTICVTLDDYFQDYNHLRPNNFEMVINEAQKLLAKRYIRALL-SKRLSKPRAECDAITRKIKTE 631
            :...|..::.:.|..:..|....:.::.:.:::|...|::|.: ||.:.|...|...:..::.::
 Frog   628 MRITCEKVELFNQHLSMARAPVCQFLLAQTERMLVIEYVKAFMHSKMVCKSSLERQQMAERMSSD 692

  Fly   632 AKRFKLFFEKIAPKISLSDSPLDL-ISTLSALLSSDIELLVLDLHTLLGSYPSLNEDHLVRLFYI 695
            |:..:....::..:.|....||.| |..:.||  .|..||.|::..|:.|:|.:::||::.|..:
 Frog   693 AEELRAALSRMGLEESTLCVPLILSIQEIFAL--KDPSLLSLEVSGLMTSFPDISDDHVLALMEL 755

  Fly   696 RNDVKAAEVREKVQDAMKSK 715
            |.|| :.::|..|.:.|:.:
 Frog   756 RGDV-SRDLRHTVLNMMQQQ 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec6	NP_611351.1	Sec6	179..731	CDD:450399	135/546 (25%)
exoc3l1	XP_002931727.3	Sec6	239..786	CDD:450399	135/546 (25%)