DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Atg7 and UBA6

DIOPT Version :10

Sequence 1:NP_611350.1 Gene:Atg7 / 37141 FlyBaseID:FBgn0034366 Length:684 Species:Drosophila melanogaster
Sequence 2:NP_060697.4 Gene:UBA6 / 55236 HGNCID:25581 Length:1052 Species:Homo sapiens


Alignment Length:414 Identity:86/414 - (20%)
Similarity:137/414 - (33%) Gaps:121/414 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   279 QSENIKFVGWELNKNGKMGPRMVCMRDSMDPAKLAENSVNLNLKLMKWRLVPDLNLEIISQTKCL 343
            |.|......|......|..|.|......:|.|..:.....|.          |..::.::::...
Human    11 QGEEASCSSWGTGSTNKNLPIMSTASVEIDDALYSRQRYVLG----------DTAMQKMAKSHVF 65

  Fly   344 LFGAGTLGCAVARNLLSWGFKHITLLDSGK-----VGFSNPVRQNLYTHADAVAGNRMKATTAAQ 403
            |.|.|.||..:|:||:..|.|.:|:.|:.|     :|      .|.:...|.|...|.:|....:
Human    66 LSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLG------TNFFLSEDDVVNKRNRAEAVLK 124

  Fly   404 RLKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRWLPTL 468
            .:.|:||      ||       |....|:.......|..::|.     ...:||:.:    ||  
Human   125 HIAELNP------YV-------HVTSSSVPFNETTDLSFLDKY-----QCVVLTEMK----LP-- 165

  Fly   469 LGAAKEKI------------VINAALGFDSYLVMRHGTTRKEAGDDGQEIEGLKCINGDQLGCYF 521
               .::||            .|:|.:         ||...:...|.|.|.|.|. ..|::....|
Human   166 ---LQKKINDFCRSQCPPIKFISADV---------HGIWSRLFCDFGDEFEVLD-TTGEEPKEIF 217

  Fly   522 CNDVTAPGNSLKDRTLDQQCTVTRPGVSNIAASYAVELLVALLQHPRKELAPAYYAQSGRGRSEE 586
            .:::|.                ..||:           :..|..||.|       .::|:..   
Human   218 ISNITQ----------------ANPGI-----------VTCLENHPHK-------LETGQFL--- 245

  Fly   587 TEEKVPEGLLGILPHSIRGMLCNYENILPATQKFAQCIACSAAVLNEYKKEGHAFLFKTFETAKF 651
            |..:: .|:.|     :.|.:.....|.|    |:..|. ....|..|...|.|...||.:|. |
Human   246 TFREI-NGMTG-----LNGSIQQITVISP----FSFSIG-DTTELEPYLHGGIAVQVKTPKTV-F 298

  Fly   652 LEDLTGISEFKRLNSEIIDFDDEE 675
            .|.|.  .:.|.....|:||.:.|
Human   299 FESLE--RQLKHPKCLIVDFSNPE 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atg7NP_611350.1 E1_like_apg7 11..682 CDD:273590 86/414 (21%)
UBA6NP_060697.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21 2/9 (22%)
Ube1 38..1046 CDD:273603 80/387 (21%)

Return to query results.
Submit another query.