Protein Alignment Atg7 and Nae1

DIOPT Version :10

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_659180.1
• Gene: Nae1 / 234664
• MGIID: 2384561
• Length: 534
• Species: Mus musculus
• Alignment Length: 328
• Identity: 65/328 - (19%)
• Similarity: 108/328 - (32%)
• Gaps: 119/328 - (36%)

  Fly   309 PAKLAENSVNLNLKLMKW----RLVPDLNLEIISQTKCLLFGAGTLGCAVARNLLSWGFKHITLL 369
            |.|:        ||..|:    ||..|...|.:......|..|...|..:.:||:..|....|::
Mouse     4 PGKI--------LKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTII 60

  Fly   370 DSGKVGFSNPVRQNLYTHADAVAGNRMKATTAAQRLKEINPSAETAGYVLEIPMPGHTIGESLLA 434
            | |.:........|.:....::..||.:|  |.:.|:|:| |..:..:|.|.|       |:||
Mouse    61 D-GNLVSGEDAGNNFFLQKSSIGKNRAQA--AMEFLQELN-SDVSGSFVEESP-------ENLL- 113

  Fly   435 QTKEHLKVIEKLVQDHD-------VIFLLTDSRESRWLPTLLGAAKEKIVINAAL---------- 482
                          |:|       .|.:.|...||    |||..|  .::.|:.:
Mouse   114 --------------DNDPSFFCRFTIVVATQLLES----TLLRLA--DVLWNSQIPLLICRTYGL 158

  Fly   483 -GFDSYLVMRHGTTRKEAGDDGQEIEGLKCINGDQLGCYFCNDVTAPGNSLKDRTLDQQCTVTRP 546
             |:...::..|......                             |.|:|:|..||:..    |
Mouse   159 VGYMRIIIKEHPVIESH-----------------------------PDNALEDLRLDKPF----P 190

  Fly   547 GVSNIAASYAVE-------------LLVALLQHPRKELAPAYYAQSGR-----GRSEETEEKVPE 593
            .:.....||.::             :::|      |.||..|...:||     ...|:..:.:.:
Mouse   191 ELREHLQSYDLDHMEKKDHSHTPWIVIIA------KYLAQWYNETNGRIPKSYKEKEDFRDLIRQ 249

  Fly   594 GLL 596
            |:|
Mouse   250 GIL 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	E1_like_apg7	11..682	CDD:273590	65/328 (20%)
Nae1	NP_659180.1	APPBP1_RUB	11..532	CDD:238770	61/313 (19%)
		Interaction with UBA3. /evidence=ECO:0000250	331..344