Protein Alignment Atg7 and atg-7

DIOPT Version :10

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_502064.1
• Gene: atg-7 / 178005
• WormBaseID: WBGene00010882
• Length: 647
• Species: Caenorhabditis elegans
• Alignment Length: 675
• Identity: 251/675 - (37%)
• Similarity: 377/675 - (55%)
• Gaps: 43/675 - (6%)

  Fly    11 FAPWESFVSPTFWHKLAELKLDHDRLSDSKRSITGHYTNRNASG--CLLEVDYTAYNRMAKPPKF 73
            |.|:.:.:...||:::.:.||:..:|.::.:.|:...:.....|  |.|.:.|.:.:.:......
 Worm     4 FVPFVTCLDTGFWNEVNKKKLNDWKLDETPKCISSQLSLHQTEGFKCHLSLSYDSLSSLESTTGL 68

  Fly    74 SHSAIGTIYNKNTIEEFKALDKLQLLADEGKELLADMCSGGALRDPSLLTRFFVLSFADLKCHSY 138
            |.|  ||:...||||.||.:||..|:..|.:::...:.:...|::|.||::||:::|||||...|
 Worm    69 SMS--GTLLLYNTIESFKMVDKSDLIRSEAEKIWESITTRKWLQNPRLLSQFFIIAFADLKKFKY 131

  Fly   139 YYWFAFPCPLTPTLKLQGAVQKLRDLPNSSSYIMALKALPTESQNF-FILYANVEKNIFEARSLS 202
            |||...|..:.|: :::..:..|..|......:...    ....|| ..||:.....:.|   ||
 Worm   132 YYWTCVPALVYPS-EIKQEITPLSSLGADHKILFDF----YRKNNFPIFLYSKQSSKMLE---LS 188

  Fly   203 SLDDKN--VEFCYFGFADPSEYEHPA-WIMRNYAAFLLQQCPSFVGKPLKFLGLRHNQQMNIDDS 264
            .|::..  .|.|.. .||||...:.| |::||..|.:....|::  |....:.||....:.|  .
 Worm   189 ELENNTNPDEICVV-VADPSPVAYSAGWMVRNVLAAVAHLHPTW--KHCHIISLRSADSIGI--K 248

  Fly   265 LVWKVIQTEACDLSQSENI--KFVGWELNKNGKMGPRMVCMRDSMDPAKLAENSVNLNLKLMKWR 327
            ..|.:...| |....::|.  |.||||.|.|.|:.|..|.:....||..|.|.||:|||.|:|||
 Worm   249 YTWTLPSAE-CSADGAQNAVPKAVGWERNANDKLQPISVDLSKEFDPKILMERSVDLNLSLIKWR 312

  Fly   328 LVPDLNLEIISQTKCLLFGAGTLGCAVARNLLSWGFKHITLLDSGKVGFSNPVRQNLYTHADAVA 392
            |.||:.||..||.|.|:.|||||||.:||.|:.||.:||:.||:..|.::|||||:|....||..
 Worm   313 LHPDIQLERYSQLKVLILGAGTLGCNIARCLIGWGVRHISFLDNSTVSYNNPVRQSLSEFEDARL 377

  Fly   393 GNRMKATTAAQRLKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKLVQDHDVIFLLT 457
            | |.||.||...::.|.||.:...:.|.:|||||:|.|..:.:.::.:..:|:||:||||:||..
 Worm   378 G-RGKAETAQAAIQRIFPSIQATAHRLTVPMPGHSIDEKDVPELEKDIAKLEQLVKDHDVVFLAL 441

  Fly   458 DSRESRWLPTLLGAAKEKIVINAALGFDSYLVMRHGT-TRKEAGDDGQEIEGLKCINGDQLGCYF 521
            ||||:|||||:|.:..:||.|:.|:|||:|:::|||. :|.|:..|   :.....:...||.|||
 Worm   442 DSREARWLPTVLASRHKKIAISVAIGFDTYVIIRHGIGSRSESVSD---VSSSDSVPYSQLSCYF 503

  Fly   522 CNDVTAPGNSLKDRTLDQQCTVTRPGVSNIAASYAVELLVALLQHPRKELAPAYYAQSGRGRSEE 586
            |:||||||||..||||||||||.|||.|.||:..|||||.::||:|.....||       ...:.
 Worm   504 CSDVTAPGNSTFDRTLDQQCTVARPGTSMIASGIAVELLSSVLQYPDPLKTPA-------SHDDN 561

  Fly   587 TEEKVPEGLLGILPHSIRGMLCNYENILPATQKFAQCIACSAAVLNEYKKEGHAFLFKTFETAKF 651
            |.      :||..||.|||.|..::.|||:.::|.||:||..|:..::::.|..|:.....:...
 Worm   562 TT------VLGAAPHQIRGFLGRFQQILPSVKRFDQCVACGDAIAAQFQQNGWKFVRDVMNSPGR 620

  Fly   652 LEDLTGISEFKR-LNSEIIDFDDEE 675
            ||::||:.|.:. :|:..|||:|:|
 Worm   621 LEEVTGLDELQNSVNAIDIDFEDDE 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	E1_like_apg7	11..682	CDD:273590	251/675 (37%)
atg-7	NP_502064.1	E1_like_apg7	4..635	CDD:273590	245/663 (37%)