Protein Alignment Atg7 and SAE1

DIOPT Version :10

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_005491.1
• Gene: SAE1 / 10055
• HGNCID: 30660
• Length: 346
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 61/298 - (20%)
• Similarity: 105/298 - (35%)
• Gaps: 52/298 - (17%)

  Fly   314 ENSVNLNLKLMKWRLVPDLNLEIISQTKCLLFGAGTLGCAVARNLLSWGFKHITLLDSGKVGFSN 378
            |.:...:.::..|.|.....|.   .::.||.|...||..:|:||:..|.|.:|:||..:|...:
Human    14 EEAAQYDRQIRLWGLEAQKRLR---ASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPED 75

  Fly   379 PVRQNLYTHADAVAGNRMKATTAAQRLKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVI 443
            |..|.| ....:|..||.:|  :.:|.:.:||..:                  :...|::..|..
Human    76 PGAQFL-IRTGSVGRNRAEA--SLERAQNLNPMVD------------------VKVDTEDIEKKP 119

  Fly   444 EKLVQDHDVIFLLTDSRESRWLPTLLGAAKEKIVI--------NAALGFDSYLVMRHGTTRKEAG 500
            |......|.:.|...||:              :::        |:...|...:...||.|....|
Human   120 ESFFTQFDAVCLTCCSRD--------------VIVKVDQICHKNSIKFFTGDVFGYHGYTFANLG 170

  Fly   501 DDGQEIEGLKCINGDQLGCYFCNDVTAPGNSLKDRTLDQQCTVTRPGVSNIAASYAVELLVALLQ 565
            :.....|..|.....| |.....|.........:.|:.::..|..|....:...::.|...|.|:
Human   171 EHEFVEEKTKVAKVSQ-GVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALK 234

  Fly   566 HPRK-----ELAPAYYAQSGRGRSEETEEKVPEGLLGI 598
            ....     ::...:....||..|.:|.|:..|.||.|
Human   235 RTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQI 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	E1_like_apg7	11..682	CDD:273590	61/298 (20%)
SAE1	NP_005491.1	Aos1_SUMO	16..341	CDD:238769	60/296 (20%)