Protein Alignment Atg7 and UBA2

DIOPT Version :10

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_005490.1
• Gene: UBA2 / 10054
• HGNCID: 30661
• Length: 640
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 49/204 - (24%)
• Similarity: 78/204 - (38%)
• Gaps: 43/204 - (21%)

  Fly   335 EIISQTKCLLFGAGTLGCAVARNLLSWGFKHITLLDSGKVGFSNPVRQNLYTHADAVAGNRMKAT 399
            |.::..:.|:.|||.:||.:.:||:..||.||.|:|...:..||..||.|:.....   .|.||.
Human    13 EAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHV---GRSKAQ 74

  Fly   400 TAAQRLKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRW 464
            .|.:.:.:..|.|....|...|..|.:.:                :..:...::....|:|.:|
Human    75 VAKESVLQFYPKANIVAYHDSIMNPDYNV----------------EFFRQFILVMNALDNRAAR- 122

  Fly   465 LPTLLGAAKEKIVINAALGFDSYLVMRHGTTRKEAGDDGQEIEGLKCINGDQLGCYFCN----DV 525
                      ..|....|..|..|: ..||    ||..||    :..|......||.|:    ..
Human   123 ----------NHVNRMCLAADVPLI-ESGT----AGYLGQ----VTTIKKGVTECYECHPKPTQR 168

  Fly   526 TAPGNSLKD 534
            |.||.::::
Human   169 TFPGCTIRN 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	E1_like_apg7	11..682	CDD:273590	49/204 (24%)
UBA2	NP_005490.1	Uba2_SUMO	19..444	CDD:238766	48/198 (24%)
		UBA_E1_SCCH	179..362	CDD:463157
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..231
		UAE_UbL	452..538	CDD:464286
		UBA2_C	549..635	CDD:465058
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	551..640