DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pcl and phf2

DIOPT Version :10

Sequence 1:NP_476672.1 Gene:Pcl / 37069 FlyBaseID:FBgn0003044 Length:1043 Species:Drosophila melanogaster
Sequence 2:NP_593209.1 Gene:phf2 / 2542236 PomBaseID:SPAC30D11.08C Length:538 Species:Schizosaccharomyces pombe


Alignment Length:431 Identity:78/431 - (18%)
Similarity:127/431 - (29%) Gaps:159/431 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   142 PVQSYYLPSGGGQTAGQINLLAASGTGKQLQPPPLVPV----TNSTSPPSTVVLDRINICINNHY 202
            |..|||...||...|.....   ...|.:..|..|.|.    ..|.....:|::|:....|.|..
pombe     2 PNSSYYDDDGGSFEAASYPF---QFDGSRRFPNDLHPTMFEGEESNQNGGSVLIDQAFQDIQNPN 63

  Fly   203 TETPTSLSSSLTTAQQP---SPIIPAIQHKAILPLIDSSTADSSSCSS------SSVSSSSY--- 255
            ..:...|.:......:|   |....:.::..:...|:||....:...|      ...|||:|   
pombe    64 VNSNMHLENQFQHFHEPNKESGAFGSYKNDDVAKEIESSKNQETDAKSEQAPFTEDASSSNYAHH 128

  Fly   256 -SGTATTSAAVVIVDEPDSTTTTPQTPPTTPEAMSSPGKSSPSPPLLATQSLLKGVNSMKPSFKT 319
             |..:.|.:|:               ||..      |..|||.||:....::.:     |.|:  
pombe   129 RSADSQTKSAL---------------PPNV------PASSSPLPPMSIAMNIAR-----KRSW-- 165

  Fly   320 VEAAPPTPPTPPSPPPPPPAPPVAAPSPAVTYALQEDVFIKCNDGRFYLGTIIDQTSDQYLIRFD 384
                                       || :.|::.                 |.|:|......|
pombe   166 ---------------------------PA-SLAIER-----------------DNTADALFSTED 185

  Fly   385 DQSEQWCEPDKLRKLGGGSSITAGGGGASTTESTNTSP--------SGP----------MCVACK 431
            .:.||:       .|.|..:    ..|.......:..|        .||          .|..|:
pombe   186 GREEQF-------NLEGVKT----KSGRKVHRPNHFDPLVKLPTRRRGPGRRPVVALAMKCSVCQ 239

  Fly   432 R--SDIEDVVEICERCGRGYHRGCTVEIVTG------SGIWSCKRCAKPMKMQQPV--------- 479
            |  |..::.:..|:.|...:|:.|....::.      :|.|.|..|.: .|.|.|:         
pombe   240 RLQSPPKNRIVFCDGCNTPFHQLCHEPYISDELLDSPNGEWFCDDCIR-RKKQAPLVTGTTAREL 303

  Fly   480 --------SHKITKPAG-------ICRQL----PYHADKLS 501
                    |:.::.|..       .|.||    |:::.|.|
pombe   304 NLSSEEKKSYLLSLPISQLVDILLFCEQLHPDIPFYSPKTS 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PclNP_476672.1 PRK12323 <13..107 CDD:481241
Tudor_dPCL-like 350..401 CDD:410523 8/50 (16%)
PHD_SF 426..469 CDD:473978 11/50 (22%)
PHD2_MTF2_PHF19_like 514..565 CDD:276978
Mtf2_C 985..1033 CDD:464077
phf2NP_593209.1 PHD_Phf1p_Phf2p_like 234..285 CDD:276977 11/50 (22%)
Blue background indicates that the domain is not in the aligned region.

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