Protein Alignment Pcl and phf1

DIOPT Version :10

• Sequence 1: NP_476672.1
• Gene: Pcl / 37069
• FlyBaseID: FBgn0003044
• Length: 1043
• Species: Drosophila melanogaster
• Sequence 2: NP_587831.1
• Gene: phf1 / 2539406
• PomBaseID: SPCC4G3.07C
• Length: 461
• Species: Schizosaccharomyces pombe
• Alignment Length: 568
• Identity: 111/568 - (19%)
• Similarity: 172/568 - (30%)
• Gaps: 215/568 - (37%)

  Fly   223 IPAIQHKAILPLIDSSTADSSSCSSSSVSSSSYSGTATTSAAVVIVDEPDSTTTTPQTPPTTPEA 287
            :|.:..:.::...|||..|:|..:|.       ||.:..........:......||....|.| |
pombe    31 LPQVSAQGVVRETDSSNFDASPVASG-------SGISDVGPFGADFHQLQQHVQTPYGGMTMP-A 87

  Fly   288 MSSPGKSSPSPPLLATQSLLKGVNSMKPSFKTVEAAPPTPPTPPSPPPPPPAPPVAAPSPAVTY- 351
            .||.|.:|                                           .||...||.:|::
pombe    88 SSSSGATS-------------------------------------------VPPEQDPSLSVSFN 109

  Fly   352 ALQEDVFIKCNDGRFYLGTIIDQTSDQYLIRFDDQSEQWCEPDKLRKLGGGSSITAGGGGASTTE 416
            .|.:....|..:||.....   :..|..:..:|....:..|.|...........|..|.......
pombe   110 RLPKSASTKTKNGRIRSSR---REDDNRIPFYDLDVAEGAEDDLQEDFHVEGMKTKSGRKIQRPV 171

  Fly   417 STNTSPSGPMCVACKRSDIE-DVVEICERCGRGYHRGCTVEIVTGSGIWSCKRCAKPMKMQQPVS 480
            :.|     |...|.||...: |:|.:|..|.||:                           .|:|
pombe   172 AYN-----PNATALKRKSRKVDMVTLCSVCQRGH---------------------------SPLS 204

  Fly   481 HKITKPAGICRQLPYHADKLSWDEKHRVNEEQIYCYCGKPGKFDHNMLQCCKCRNWFHTQCMQNF 545
            ::|....| |.. |||.                  .|..| ..|...:|.... .||..:|....
pombe   205 NRIVFCDG-CNS-PYHQ------------------LCHHP-PIDDATVQDVDA-EWFCMKCQYRR 247

  Fly   546 KKKLLRGDMFFVFCCTVCNNGI-EFVRRMQIEWVDVLHIA--------------LYNLRKHQHQK 595
            .|:.|...|      |..:.|: |..::|.:..:...|:|              :||.|..:
pombe   248 AKQPLETGM------TAQDLGLSESDKKMYLSSLPTPHLADLILFCEKSYPSLPIYNPRTRE--- 303

  Fly   596 YHHLLNDIWPFILEQRHQLPICEKWRTLPETALMERL--KQ----------------------TL 636
               ||.:|       ||||.:..:.:   :.:|.|||  ||                      ||
pombe   304 ---LLGEI-------RHQLLVSSERQ---QISLQERLHAKQDEAPSDEPAPVPYTASYVANSGTL 355

  Fly   637 KDYSDRFVCGREFKRAPAF--YALRHSGPPHIPKVF--------LEP--HEELSD---------E 680
            .||             |..  .|:|::..|...::|        |.|  |:..|:         :
pombe   356 YDY-------------PTLIRLAIRNTLSPSKDEIFNWLAQNVPLLPTFHDSASEAIRWMVNKGQ 407

  Fly   681 LLEKR--FKLMLMPEEPDEGANELP-----KRVPKDV-YEFNTDEDDP 720
            |:...  :::..:.|.|....:.||     ::|||.| ..|.|  |||
pombe   408 LVRSGSIYQIATVEEYPHLQPSLLPTFQRNRKVPKLVPVSFPT--DDP 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pcl	NP_476672.1	PRK12323	<13..107	CDD:481241
		Tudor_dPCL-like	350..401	CDD:410523	8/51 (16%)
		PHD_SF	426..469	CDD:473978	9/43 (21%)
		PHD2_MTF2_PHF19_like	514..565	CDD:276978	11/50 (22%)
		Mtf2_C	985..1033	CDD:464077
phf1	NP_587831.1	PHD_Phf1p_Phf2p_like	192..243	CDD:276977	18/99 (18%)