Protein Alignment PIG-A and ALG1

DIOPT Version :9

• Sequence 1: NP_001286547.1
• Gene: PIG-A / 37020
• FlyBaseID: FBgn0034270
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_061982.3
• Gene: ALG1 / 56052
• HGNCID: 18294
• Length: 464
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 50/267 - (18%)
• Similarity: 96/267 - (35%)
• Gaps: 91/267 - (34%)

  Fly   109 VGSLLGLKTVFTDHSLFGFADLS--------AALTNNLLEVNLGMVNHA-ICVSHIGKE----NT 160
            ||.|.|.|.|...|: :|::.:.        ..|.....|...|.::|. :||::..:|    |.
Human   144 VGCLCGSKLVIDWHN-YGYSIMGLVHGPNHPLVLLAKWYEKFFGRLSHLNLCVTNAMREDLADNW 207

  Fly   161 VLRARVA---------------KHRVSVIPNAVDT---ALFTP-DP------------------- 187
            .:||...               :||:.:...::.:   |...| ||
Human   208 HIRAVTVYDKPASFFKETPLDLQHRLFMKLGSMHSPFRARSEPEDPVTERSAFTERDAGSGLVTR 272

  Fly   188 -QQRPSNDIINIVVASRLVYRKGIDLLAGIIPRFK-------NTPNINFIIVGDGPKRDLLEEIR 244
             ::||:    .:|.::.....:...:|...:.:|:       |.|::..:|.|.||.|:....:.
Human   273 LRERPA----LLVSSTSWTEDEDFSILLAALEKFEQLTLDGHNLPSLVCVITGKGPLREYYSRLI 333

  Fly   245 EKTNMQERVQMVGAVEHNRVRDFLVRGHIFLNTSLTEA--YCMAIVEAASCGLQVVSTSVGGIPE 307
            .:.:.|                     ||.:.|...||  |.: ::.:|..|: .:.||..|:.
Human   334 HQKHFQ---------------------HIQVCTPWLEAEDYPL-LLGSADLGV-CLHTSSSGLD- 374

  Fly   308 VLPKSLI 314
             ||..::
Human   375 -LPMKVV 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-A	NP_001286547.1	RfaB	1..309	CDD:223515	48/260 (18%)
		GT1_PIG-A_like	2..451	CDD:99970	50/267 (19%)
ALG1	NP_061982.3	PLN02275	27..424	CDD:215155	50/267 (19%)
		GT1_ALG1_like	30..461	CDD:99986	50/267 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	243..262		4/18 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900