Protein Alignment PIG-A and ALG1

DIOPT Version :10

• Sequence 1: NP_611257.1
• Gene: PIG-A / 37020
• FlyBaseID: FBgn0034270
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_061982.3
• Gene: ALG1 / 56052
• HGNCID: 18294
• Length: 464
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 50/267 - (18%)
• Similarity: 96/267 - (35%)
• Gaps: 91/267 - (34%)

  Fly   109 VGSLLGLKTVFTDHSLFGFADLS--------AALTNNLLEVNLGMVNHA-ICVSHIGKE----NT 160
            ||.|.|.|.|...|: :|::.:.        ..|.....|...|.::|. :||::..:|    |.
Human   144 VGCLCGSKLVIDWHN-YGYSIMGLVHGPNHPLVLLAKWYEKFFGRLSHLNLCVTNAMREDLADNW 207

  Fly   161 VLRARVA---------------KHRVSVIPNAVDT---ALFTP-DP------------------- 187
            .:||...               :||:.:...::.:   |...| ||
Human   208 HIRAVTVYDKPASFFKETPLDLQHRLFMKLGSMHSPFRARSEPEDPVTERSAFTERDAGSGLVTR 272

  Fly   188 -QQRPSNDIINIVVASRLVYRKGIDLLAGIIPRFK-------NTPNINFIIVGDGPKRDLLEEIR 244
             ::||:    .:|.::.....:...:|...:.:|:       |.|::..:|.|.||.|:....:.
Human   273 LRERPA----LLVSSTSWTEDEDFSILLAALEKFEQLTLDGHNLPSLVCVITGKGPLREYYSRLI 333

  Fly   245 EKTNMQERVQMVGAVEHNRVRDFLVRGHIFLNTSLTEA--YCMAIVEAASCGLQVVSTSVGGIPE 307
            .:.:.|                     ||.:.|...||  |.: ::.:|..|: .:.||..|:.
Human   334 HQKHFQ---------------------HIQVCTPWLEAEDYPL-LLGSADLGV-CLHTSSSGLD- 374

  Fly   308 VLPKSLI 314
             ||..::
Human   375 -LPMKVV 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-A	NP_611257.1	GT4_PIG-A-like	2..451	CDD:340827	50/267 (19%)
ALG1	NP_061982.3	GT33_ALG1-like	30..461	CDD:340843	50/267 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	243..262		4/18 (22%)