Protein Alignment PIG-A and piga-1

DIOPT Version :10

• Sequence 1: NP_611257.1
• Gene: PIG-A / 37020
• FlyBaseID: FBgn0034270
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_495840.1
• Gene: piga-1 / 174386
• WormBaseID: WBGene00008431
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 473
• Identity: 214/473 - (45%)
• Similarity: 283/473 - (59%)
• Gaps: 62/473 - (13%)

  Fly     3 ICMVSDFFYPSIGGVEEHVYNLSQMLLSLGHKIVVLTHAYGDCSGIRYVTGYLKVYYLPIKVCYN 67
            |.:|||||.|:.||||.|:|.|:|.|:.|||::||:||.||:..||||::..|||||||..|.||
 Worm    10 IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPFIVAYN 74

  Fly    68 QCILPTAVCNVPMLRAVLLRERVEVVHGHSAFSALAHEALMVGSLLGLKTVFTDHSLFGFADLSA 132
            ...|.:.|.::|.||.|||||.|:::||||.||:||||.||:|.|:||:|||||||||||||.||
 Worm    75 GATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSLFGFADASA 139

  Fly   133 ALTNNL-LEVNLGMVNHAICVSHIGKENTVLRARVAKHRVSVIPNAVDTALFTPDPQQRPSNDII 196
            .|||.| |:.:|..|:..||||:..|||||||.::..::||.||||::|:|||||..|. .|:..
 Worm   140 ILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTPDRNQF-FNNPT 203

  Fly   197 NIVVASRLVYRKGIDLLAGIIPRF-KNTPNINFIIVGDGPKRDLLEEIREKTNMQERVQMVGAVE 260
            .||...|||||||.|||..|:|:. ....::.|||.||||||..|||:.|:..:.|||.::|.:.
 Worm   204 TIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLP 268

  Fly   261 HNRVRDFLVRGHIFLNTSLTEAYCMAIVEAASCGLQVVSTSVGGIPEVLP-KSLILLAEPEIDAI 324
            ||:|:..|.:|.||:|||||||:||:|||||||||.||||.|||:||||| ...|.|.||..|.:
 Worm   269 HNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDL 333

  Fly   325 YAAILIAIDRHRKSSFKVSPSVGNGHLASDANGKVKRRRRRKVDTPISPTQLPAVSAPPADQNSS 389
            ..|:|.|:||..|..
 Worm   334 VDALLKAVDRREKGL-------------------------------------------------- 348

  Fly   390 TEPVMCPYRCNELVETLYNWEDVALRTVKVYDRVLNERSFTTSELVFAVWQHGSWFLVFFVVAH- 453
               :|.|...:|.|..:|||.|||.||..:|.:.:..........:...:..|..|.:.::|..
 Worm   349 ---LMDPTEKHEAVSKMYNWPDVAARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVVSC 410

  Fly   454 ---FLMRLLELW-RPRKH 467
               |.:.:|:|: .|||:
 Worm   411 IIIFWLTVLDLFDSPRKN 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-A	NP_611257.1	GT4_PIG-A-like	2..451	CDD:340827	207/450 (46%)
piga-1	NP_495840.1	GT4_PIG-A-like	9..408	CDD:340827	207/451 (46%)