Protein Alignment: PIG-A and piga-1

• Sequence 1: NP_001286547.1
• Gene: PIG-A
• FlyBaseID: FBgn0034270
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_495840.1
• Gene: piga-1
• WormBaseID: WBGene00008431
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 473
• Identity: 214/474 (45%)
• Similarity: 283/474 (60%)
• Gaps: 62/474 (13%)

  Fly     3 ICMVSDFFYPSIGGVEEHVYNLSQMLLSLGHKIVVLTHAYGDCSGIRYVTGYLKVYYLPIKVCYN 67
            |.:|||||.|:.||||.|:|.|:|.|:.|||::||:||.||:..||||::..|||||||..|.||
 Worm    10 IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPFIVAYN 74

  Fly    68 QCILPTAVCNVPMLRAVLLRERVEVVHGHSAFSALAHEALMVGSLLGLKTVFTDHSLFGFADLSA 132
            ...|.:.|.::|.||.|||||.|:::||||.||:||||.||:|.|:||:|||||||||||||.||
 Worm    75 GATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSLFGFADASA 139

  Fly   133 ALTNNL-LEVNLGMVNHAICVSHIGKENTVLRARVAKHRVSVIPNAVDTALFTPDPQQRPSNDII 196
            .|||.| |:.:|..|:..||||:..|||||||.::..::||.||||::|:|||||..|. .|:..
 Worm   140 ILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTPDRNQF-FNNPT 203

  Fly   197 NIVVASRLVYRKGIDLLAGIIPRF-KNTPNINFIIVGDGPKRDLLEEIREKTNMQERVQMVGAVE 260
            .||...|||||||.|||..|:|:. ....::.|||.||||||..|||:.|:..:.|||.::|.:.
 Worm   204 TIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLP 268

  Fly   261 HNRVRDFLVRGHIFLNTSLTEAYCMAIVEAASCGLQVVSTSVGGIPEVLP-KSLILLAEPEIDAI 324
            ||:|:..|.:|.||:|||||||:||:|||||||||.||||.|||:||||| ...|.|.||..|.:
 Worm   269 HNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDL 333

  Fly   325 YAAILIAIDRHRKSSFKVSPSVGNGHLASDANGKVKRRRRRKVDTPISPTQLPAVSAPPADQNSS 389
            ..|:|.|:||..|..
 Worm   334 VDALLKAVDRREKGL-------------------------------------------------- 348

  Fly   390 TEPVMCPYRCNELVETLYNWEDVALRTVKVYDRVLNERSFTTSELVFAVWQHGSWFLVFFVVAH- 453
               :|.|...:|.|..:|||.|||.||..:|.:.:..........:...:..|..|.:.::|..
 Worm   349 ---LMDPTEKHEAVSKMYNWPDVAARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVVSC 410

  Fly   454 ---FLMRLLELW-RPRKH 467
               |.:.:|:|: .|||:
 Worm   411 IIIFWLTVLDLFDSPRKN 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-A	NP_001286547.1	RfaB	1..309	CDD:223515	179/308 (58%)
		GT1_PIG-A_like	2..451	CDD:99970	207/451 (46%)
piga-1	NP_495840.1	GT1_PIG-A_like	9..409	CDD:99970	208/453 (46%)
		RfaB	10..383	CDD:223515	205/427 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C150351582
eggNOG	1	0.900				E1_COG0438
Hieranoid	1	1.000
Homologene	1	1.000				H1982
Inparanoid	1	1.050	367	1.000	Inparanoid score	I1243
Isobase	1	0.950		0	Normalized mean entropy	S691
OMA	1	1.010
OrthoDB	1	1.010				D305260at33208
OrthoFinder	1	1.000				FOG0004176
OrthoInspector	1	1.000				T476743
orthoMCL	1	0.900				OOG5_127105
Panther	1	1.100			LDO	PTHR45871
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R517
TreeFam	1	0.960
	15	14.750