DRSC/TRiP Functional Genomics Resources

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Protein Alignment POSH and BEM1

DIOPT Version :10

Sequence 1:NP_523776.1 Gene:POSH / 36990 FlyBaseID:FBgn0040294 Length:838 Species:Drosophila melanogaster
Sequence 2:NP_009759.3 Gene:BEM1 / 852499 SGDID:S000000404 Length:551 Species:Saccharomyces cerevisiae


Alignment Length:373 Identity:74/373 - (19%)
Similarity:112/373 - (30%) Gaps:151/373 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   139 HAYALFDFASGEATDLKFKKGDLILIKHRIDNNWFVGQANGQ---EGTFPINYVKV--------- 191
            :|..|:||.:.:|.:|....|:.:.|....:..||:.:..|:   .|..|:.:|.:         
Yeast   159 YAIVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSIIDIATGYAT 223

  Fly   192 ---------SVPLPMPQ----CIAMYDF------------------------------------- 206
                     ||.||..|    .||.|..                                     
Yeast   224 GNDVIEDIKSVNLPTVQEWKSNIARYKASNISLGSVEQQQQQSITKPQNKSAKLVDGELLVKASV 288

  Fly   207 -KMGPNDEE----GCLEFKKSTVIQVMRRVDHNWAEGRIGQTIGIFPIAFVELNAAAKKLLDSGL 266
             ..|..||:    .|.|.......| ::|...::.:.:: |.:..||       |.|.||.|:| 
Yeast   289 ESFGLEDEKYWFLVCCELSNGKTRQ-LKRYYQDFYDLQV-QLLDAFP-------AEAGKLRDAG- 343

  Fly   267 HTHPFCHPPKQQGQRALPPVPVIDPTVVTESSSGSSNSTPGSSNSSSTSSSNNCSPNHQISLPNT 331
                     .|..:|.:|.:|               ...|..:||.:.....:.: .:...|.|.
Yeast   344 ---------GQWSKRIMPYIP---------------GPVPYVTNSITKKRKEDLN-IYVADLVNL 383

  Fly   332 PQHVVASGSASVRFRDKGAKEKRHSLNALLGGGAP------------------------------ 366
            |.::..|             |..|||..:|..|..                              
Yeast   384 PDYISRS-------------EMVHSLFVVLNNGFDREFERDENQNNIKTLQENDTATFATASQTS 435

  Fly   367 --LSLLQTNRHSAEILSLPHELSRLEVSSSTALKPTSAPQTSRVLKTT 412
              .|..|.|..:.|.|.|..:||.|.:|.|   |...|..||. ||||
Yeast   436 NFASTNQDNTLTGEDLKLNKKLSDLSLSGS---KQAPAQSTSG-LKTT 479

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
POSHNP_523776.1 RAD18 6..>113 CDD:227719
RING-HC_SH3RF3 8..53 CDD:438408
SH3 139..191 CDD:473055 14/54 (26%)
SH3_SH3RF_2 199..251 CDD:212721 14/97 (14%)
SH3_SH3RF_3 424..477 CDD:212717
SH3_SH3RF_C 782..836 CDD:212719
BEM1NP_009759.3 SH3_Bem1p_1 76..127 CDD:212811
SH3_Bem1p_2 159..214 CDD:212812 14/54 (26%)
PX_Bem1p 284..400 CDD:132800 31/163 (19%)
PB1 478..549 CDD:214770 2/2 (100%)
Blue background indicates that the domain is not in the aligned region.

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