Protein Alignment CG4853 and AgaP_AGAP008775

DIOPT Version :9

• Sequence 1: NP_611222.2
• Gene: CG4853 / 36974
• FlyBaseID: FBgn0034230
• Length: 709
• Species: Drosophila melanogaster
• Sequence 2: XP_314901.3
• Gene: AgaP_AGAP008775 / 1275634
• VectorBaseID: AGAP008775
• Length: 462
• Species: Anopheles gambiae
• Alignment Length: 355
• Identity: 90/355 - (25%)
• Similarity: 144/355 - (40%)
• Gaps: 57/355 - (16%)

  Fly   225 GLFHSVSMSAPWSHPRDTLTDSLYCDIPSSADESDAVSILNTHLKITEPFDCQTAPVYAKDIPKK 289
            |:....::.|| ..||.....:...|.|.|...|     |.|           ...:|.......
Mosquito   133 GIVGKKTLQAP-GQPRPPNVKTSMTDGPRSLQGS-----LGT-----------GGVMYGNGTIVS 180

  Fly   290 GNLDSVVNLLINNNTKDLR----FAFLTTSRLFSPPHQLLSKIIAKIDNEE--ENVLRLLNEWLD 348
            |.|:|:::||:..|.::..    |:||.::|.|....:||.|::..|...|  |.::.||..|..
Mosquito   181 GPLESLIDLLMPGNVEEFDQEYVFSFLLSARFFIRSFELLGKLLESIPEPEPLERIVPLLGVWTR 245

  Fly   349 TCPGDFSHELLLQELENKRNVKGLAA------FLDGIPQALAQKDENGRSQLNNLLTKQSSASSL 407
            ..|.||..|.::      .:||.:.|      ..:.:||.|..           ||.:.:...:
Mosquito   246 MFPYDFRDERMM------NHVKHIVARCADTKLANVVPQLLCA-----------LLARLTELEN- 292

  Fly   408 GRQSSIKSLKRFAAN-VYKTDNVLNNCSSAFELAHQLYAIEYAYLSQIRLEEFVEI---LEKDEL 468
             .:..::|.:..|.| |.:|.....:..:|.:||..|..||......:..||||:.   |.||..
Mosquito   293 -HEEELRSYQSTADNKVGRTPTESISWPTATQLAQLLCRIERKLAKHVGPEEFVQCSPNLLKDPN 356

  Fly   469 KTCISQTKAGTLGSNCIS-----QVTIDSYVQWFNQLSYLTATEILKLGKKSQRAQMIDFWVETA 528
            :...:.......|.:..|     ...::||::|..:|..|.|.||||......|.:..:.|...|
Mosquito   357 REDFTPKPISGAGGHATSLDGKKTCNLESYLEWSARLRLLVANEILKCRNIQDRNKQFELWSGAA 421

  Fly   529 LECFNTGNFNSLMAILTALNLTAIARLKKT 558
            ..|...||:||..|||.:.:|..:|||:.|
Mosquito   422 QYCLLVGNYNSATAILESFDLPPVARLQVT 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4853	NP_611222.2	RasGEF_N	288..365	CDD:279012	24/82 (29%)
		RasGEF	438..638	CDD:279011	40/129 (31%)
AgaP_AGAP008775	XP_314901.3	RasGEF_N	177..257	CDD:279012	24/79 (30%)
		RasGEF	323..>451	CDD:279011	39/127 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3541
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D246323at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780