Protein Alignment Tes and Prickle3

DIOPT Version :10

• Sequence 1: NP_611215.1
• Gene: Tes / 36965
• FlyBaseID: FBgn0034223
• Length: 816
• Species: Drosophila melanogaster
• Sequence 2: NP_001277553.1
• Gene: Prickle3 / 54630
• MGIID: 1859635
• Length: 624
• Species: Mus musculus
• Alignment Length: 812
• Identity: 155/812 - (19%)
• Similarity: 212/812 - (26%)
• Gaps: 476/812 - (58%)

  Fly    24 SRREQLKRSKLGHEAGA-GAPCAECKDKCPGLDLHFWRKVCRNCKCPKIQH---VCPDD------ 78
            |||.:..|:....|..| |.||..|:::|||..||.|||:|::||||:.:|   ..|.|
Mouse     6 SRRRRSGRAPPEAEDPARGQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVRTVPVDLERIMC 70

  Fly    79 ------------DDATGWAQFEILGQIRAKPAYIKIKALASQPVQLEWVPPNAAPDVVTDYMEKL 131
                        ||.:|.|..|                       ..||||...|:.|..:...|
Mouse    71 RLISDFQRHSISDDDSGCASEE-----------------------YAWVPPGLKPEQVYQFFSCL 112

  Fly   132 GTAQIPVAGSDAALKRKMQLELQVPPHDLDAALCDGLTETEAIQLQQYVQKLREQCVGQGVVVRL 196
            ...::|...|.....|..||..|:||||.:|..|..|.|.|..:|:
Mouse   113 PEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELR------------------- 158

  Fly   197 GDRLNHAQVEHVAPALMPTQEAQQTWQSLGLMPVADDTLNELLANPKVAQALASPASAHPKLLVA 261
                                                                            |
Mouse   159 ----------------------------------------------------------------A 159

  Fly   262 FSEPLCESTAQFEENGALRAQTREKLLGISKPALLSLVTHGIVYDKVLGILQEKKLNISRDPKLG 326
            ||:                                                |.|:.|:.|
Mouse   160 FSQ------------------------------------------------QRKRENLGR----- 171

  Fly   327 PIAEFRKEYVNNPQFRAEINTICPQPPMTPIKSPPGTPFNSPLPLKNPVQIRMGAQMRQDTPMRR 391
                                                                             
Mouse   172 ----------------------------------------------------------------- 171

  Fly   392 VKFGGVSTIVYDCGLPANTDYDRDPVFAQILQAEPLKHAFQEARAGRAPSSVVISNIPAPVASLA 456
                  :|:
Mouse   172 ------ATV-------------------------------------------------------- 174

  Fly   457 ELRGLNPATRAQLQSVGLDKNMLQSAVSNAPYYDRLFRSLHDKGISHDQCHLLQPMKQVHDWLLD 521
                                              |:|
Mouse   175 ----------------------------------RIF---------------------------- 177

  Fly   522 DDQLLDEIDKVFADMANGCKDISYPKPSLGELPTSQSSDSGFHSKPPTPGYGSEDLTAGQGRFAS 586
                                                         |.|
Mouse   178 ---------------------------------------------PVT----------------- 180

  Fly   587 IPGIEDMNMYPSCAGMPEQFQQLRLHGDEASGKNSTRTILCADCNQPIAMGEVAVKADRAGKEIA 651
            |.|                                   .:|.:|.:.|..|::||.|.|||....
Mouse   181 ITG-----------------------------------AICEECGKQIGGGDIAVFASRAGLGAC 210

  Fly   652 WHPGCFKCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTKEYTAAEEATFHIK 716
            |||.||.|.||:|||.||:||:|.|:|:|||..|..|: |||:||||:||:.|.|.||...:|:.
Mouse   211 WHPQCFVCTTCQELLVDLIYFYHAGKVYCGRHHAECLR-PRCQACDEIIFSPECTEAEGRHWHMG 274

  Fly   717 HFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQG-VAWGDVHWHAS- 779
            ||||::|:..|.||:|:.  :.:.|.|..||:...|..|..|...|| .||| :|:...|||||
Mouse   275 HFCCFECEASLGGQRYVM--RQSRPHCCACYEARHAEYCDGCGEHIG-LDQGQMAYEGQHWHASD 336

  Fly   780 -CFVCAGVQCSKPLIGGRFCVKENMPFCSPTC 810
             ||.|:  :||:||:|..|..:..:.|||..|
Mouse   337 RCFCCS--RCSRPLLGRPFLPRRGLIFCSRAC 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604	23/86 (27%)
		LIM1_Testin_like	627..684	CDD:188726	31/56 (55%)
		LIM2_Testin_like	691..748	CDD:188727	26/56 (46%)
		LIM	755..810	CDD:413332	25/57 (44%)
Prickle3	NP_001277553.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		7/19 (37%)
		PET_Prickle	82..178	CDD:193602	38/488 (8%)
		LIM1_Prickle	186..244	CDD:188799	31/57 (54%)
		LIM2_Prickle	249..304	CDD:188802	26/56 (46%)
		LIM3_Prickle	309..367	CDD:188804	26/61 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..617