Protein Alignment Tes and PRICKLE4

DIOPT Version :10

• Sequence 1: NP_611215.1
• Gene: Tes / 36965
• FlyBaseID: FBgn0034223
• Length: 816
• Species: Drosophila melanogaster
• Sequence 2: NP_037529.3
• Gene: PRICKLE4 / 29964
• HGNCID: 16805
• Length: 384
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 84/265 - (31%)
• Similarity: 110/265 - (41%)
• Gaps: 66/265 - (24%)

  Fly   546 PKPSLGELPTSQSSDSGFHSKPPTPGYGSEDLTAGQGRFASIPGI-------EDMNMYPSCAGMP 603
            |||.....|.:..||||.     .||...|| |..||     |.:       .|.|..|:..|:.
Human    15 PKPQDPGPPANSDSDSGH-----LPGEDPED-THAQG-----PAVLSLGSLCLDTNQAPNWTGLQ 68

  Fly   604 EQFQQL-------------------------RLHGDEASGKNSTRTIL-------CADCNQPIAM 636
            ...|||                         .....||.|:...|.:|       |..|.:.:..
Human    69 TLLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKP 133

  Fly   637 GEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIF 701
            ||..|.|.|||::..||..||.|..|.:.|.:|:||:|.||::|||..|..|: |||.|||:|||
Human   134 GEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLR-PRCPACDQLIF 197

  Fly   702 TKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPAD 766
            :...|.||...:|..||||..|..||.|.:|.....|  |.|..|::..:             :|
Human   198 SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGS--PCCPSCFENRY-------------SD 247

  Fly   767 QGVAW 771
            .|.:|
Human   248 AGSSW 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	25/56 (45%)
		LIM2_Testin_like	691..748	CDD:188727	26/56 (46%)
		LIM	755..810	CDD:413332	3/17 (18%)
PRICKLE4	NP_037529.3	PET_OEBT	1..116	CDD:193603	27/111 (24%)
		LIM1_Testin_like	124..181	CDD:188726	25/56 (45%)
		LIM2_Testin_like	187..242	CDD:188727	26/56 (46%)