Protein Alignment mthl4 and LOC110439897

DIOPT Version :10

• Sequence 1: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_021333226.3
• Gene: LOC110439897 / 110439897
• -ID: -
• Length: 484
• Species: Danio rerio
• Alignment Length: 278
• Identity: 61/278 - (21%)
• Similarity: 115/278 - (41%)
• Gaps: 59/278 - (21%)

  Fly   217 VISLICII----------LTISVYLYVEKLRNLHGKCFICYLASLFLGYFFLV----LNVWKYSS 267
            ::.|:|:|          |:.::..:...:.|: .:..|| ::.|.....||:    |::.:...
Zfish   215 LLGLVCVIVGLVFFSLALLSFALCQWSPGVNNV-ARINIC-ISLLSAHLLFLLTQQFLSLIRPQQ 277

  Fly   268 GFCVTAGFLGYFSVMAAFFWLSVIGIHLRIKFSLASNCLHRL-----LPENPFRAYNLYAWGIPL 327
            ..||....|.:|..::||.|:.:..:.|.|       |:..|     ..:....:..|...|..|
Zfish   278 VLCVVIAGLLHFFFLSAFVWMFIEAVLLFI-------CVKNLSQISSKKKEVLSSGFLCVIGYVL 335

  Fly   328 IMTAITYTADQVVKNEKLRPRVGVG-KNCWI-YTGDMTVMIYFYGPMLLLIAFNIIMFVLSAIYI 390
            .|..:..:...|.:        |.| ::||| |  |...:..|.||:.:::|.|:|:|:...||:
Zfish   336 AMVVVCVSIGLVPE--------GYGSEHCWIKY--DKGFIWSFLGPVCVILALNLILFIRIVIYL 390

  Fly   391 YNIKKNVKGLVHKQQTNQQIND--QQMFAIFLRL--FILMGLSWSFEILSFLLTKQQAWARALMV 451
            .:....:         |.:|:.  |....:|..|  |:::|..|   ||.|.....:......::
Zfish   391 NSALSKL---------NAEISQLKQTKVMVFKTLVQFVVLGCPW---ILGFFTNSSEVLEIVFLI 443

  Fly   452 ADYFNWSQGTIIFVLFIL 469
               .|..|||.||:::.|
Zfish   444 ---LNSQQGTFIFLIYCL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:429053
		7tmB3_Methuselah-like	205..477	CDD:410632	61/278 (22%)
		TM helix 1	207..232	CDD:410632	4/24 (17%)
		TM helix 2	241..263	CDD:410632	6/25 (24%)
		TM helix 3	271..298	CDD:410632	7/26 (27%)
		TM helix 4	315..335	CDD:410632	4/19 (21%)
		TM helix 5	361..390	CDD:410632	9/28 (32%)
		TM helix 6	411..438	CDD:410632	8/30 (27%)
		TM helix 7	446..471	CDD:410632	7/24 (29%)
LOC110439897	XP_021333226.3	None