Protein Alignment: cnk and cnksr1

• Sequence 1: NP_001286524.1
• Gene: cnk
• FlyBaseID: FBgn0286070
• Length: 1557
• Species: Drosophila melanogaster
• Sequence 2: XP_009291361.1
• Gene: cnksr1
• ZFINID: ZDB-GENE-040426-1802
• Length: 790
• Species: Danio rerio
• Alignment Length: 992
• Identity: 197/993 (20%)
• Similarity: 337/993 (34%)
• Gaps: 318/993 (32%)

  Fly     6 IAEWTPDQVTDWIKGLDESMKGYLYEFSKQEIGGRALLNIRPYELENLGMLRIGHQEIVLEAVEN 70
            :|.|:.::||:|:||||..::  .|.||:.::.|..||.:....|||:|:.:|||||::|||||.
Zfish     4 VASWSTERVTEWLKGLDAPLQ--QYPFSEWQLSGSDLLQLSSSRLENIGVHKIGHQELILEAVEK 66

  Fly    71 LRNFHYHLKNDNLQFMALHVATAAKNLHRELA------RNHAES-TKIDTRILHDITRTIATLKP 128
            |....|.:..|:|:.:...:...|..|...:.      .|.|:| |.:..::|..:...|.....
Zfish    67 LCALTYSVGGDSLRSLTEKLRAVAHTLQMSIQGRWRVNSNDAQSATNLPQQVLQAVVDVIIASNG 131

  Fly   129 LVGSLERTPFRKQEMYREYCGNVLKCGL--ELATIAHRDRFALQPVPAIRQSAERLENLANFVIQ 191
            ||..|.|..|.:|   ..|..||....|  :|.|..|::....:....|.....:|..:.:.::.
Zfish   132 LVSVLNRYQFEQQ---TGYTANVKVAALCKDLDTNVHKETAVFEKEKDIISICRQLVAVCDEILT 193

  Fly   192 DISDPMVLQPASLNLVTLKKRE--SELGFNIESSYNGIHRVTDIKYNSPAHNSGKIEDGDEIVQI 254
            ....|::.....|..|.|....  .::|..|.::.:..|.||.|....||....||.:|||::|:
Zfish   194 VSPLPLLTHTTQLESVDLVPASPGDQVGIEITTTGSRNHFVTGIPTEFPAEICEKILEGDEVIQV 258

  Fly   255 NYQTVVGWQHRTVLEHLREALPDVVLTVKKRPKHTKMFGQIYMQPYRLPSKKRNMAARWAAQMPS 319
            |.|.||||..:.:::.|.|....|.|.|:                 |||...:...:|..::...
Zfish   259 NGQIVVGWSRKNLVKKLEENPDGVTLVVR-----------------RLPGFLKRKESRAKSEREE 306

  Fly   320 PRAAFLTLDTEQLATGGTGSAVPDPSKSLSSEKREVLTKANPVSSASDSDSSCSDIPTPTDPKLA 384
            |...                   :..||..|....|......:|.:.|.
Zfish   307 PEEG-------------------EEEKSRHSLLGRVAASVRSLSFSEDI---------------- 336

  Fly   385 AREIRLYYPKPRALLQRRNTICGCEYLSLKNSDLVVPSWHERKPGIGSPTNCDPGSPSIRDKSIS 449
                       ||||..|:               ...|.|..:                |:||
Zfish   337 -----------RALLYLRS---------------ATDSTHHFR----------------REKS-- 357

  Fly   450 FGYGLEMAARPTTCIGIAGDTSTDKARRMFHEARKLKQLTEDSQREFLVDRYKPGVSKVVRFDAK 514
                           .:|.|.|:::     :::..||:|             :||
Zfish   358 ---------------ALANDQSSNE-----YQSGTLKRL-------------QPG---------- 379

  Fly   515 EDYVMKNEKFICNVENTILETFEPIPFADEGDEDALETLRNCKTENAEELLEAINLATKGQDLPL 579
                                                                             
Zfish   380 ----------------------------------------------------------------- 379

  Fly   580 AEAINMPLLQQGRRGRLDKSHSTPAYDNSGEESDTPPAIEPRKEFLLVTPPAPPPRPRKQREMTP 644
                                            :|:|.|                  .|...|:..
Zfish   380 --------------------------------TDSPRA------------------SRNSLEVKI 394

  Fly   645 PAVPPPPPKPASMQPASSITSISIPVPVPVPAAVDPSEISELHTPSKSRTLTLKKKHSLMAKRRN 709
            .|...|.|:..:....||              ..|.:.:.|.....||.|   |...:.|::||
Zfish   395 SAERSPSPQELNRSSTSS--------------CPDMAGLREEKENKKSST---KGMRTAMSRRR- 441

  Fly   710 TNLKLLGTGDIQGHLYRRKKNHRGV---TYWARIYFVMLDTILYGFRSKQSTSASLVIFLPGFTV 771
            .:.:.||..|..|.|::::| ..||   ..|.|.:||:....||.:.|:|...|..:|.:..:.:
Zfish   442 VSCRELGRPDCDGWLWKKRK-EAGVFMTQKWQRFWFVLKGPTLYWYNSQQEEKAEGLIKIGSYNI 505

  Fly   772 SLAKEVHSKPHAFKVYHTA-KSFYFAAESLDALNQWVDFLRQASLKVPPSTGSKGGGDAKDLYSE 835
            ..|.| |.:.:.||:.|.. ::|:|||:::..:::|::.|..|..|......|:...: :|.|||
Zfish   506 ESAGE-HKRKYVFKMCHPRFQNFFFAADNVTDMSKWINCLITAIQKHKKYAQSQPDSE-EDCYSE 568

  Fly   836 NDSSGEECDALVIQNLSTPSPQGNKESMSMSMTLSGGTPPSSAPIKHERGYLDSFRKFTNTFKSS 900
            .:|..|          |:.||..:::.:.........|.|.: .:|..|     ..:.....:::
Zfish   569 TESEEE----------SSRSPLPHRKKLYTKTQTQSNTLPRT-KVKQNR-----MSEPITISQAT 617

  Fly   901 AAKPSSDIPVPTEQYRSYRKVPGGSFGIQIGANTPGYHD---PAMPPTQIPPLVGPKLSRSSSRS 962
            .:|.:.::....|.:.|.:|  ||.  ..||...|..||   .:.......|::..|:....:..
Zfish   618 GSKIAGNVDEMDEMFNSIKK--GGV--TLIGQKQPMTHDQLRKSFIKRNKNPVINEKIHTLRALQ 678

  Fly   963 SVVSGTESAVSLSASIL 979
            |.:...|:.:.|...||
Zfish   679 STLKAKEAELHLINRIL 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cnk	NP_001286524.1	SAM_CNK1,2,3-suppressor	6..74	CDD:188910	30/68 (44%)
		SAM	7..74	CDD:197735	30/67 (45%)
		CRIC_ras_sig	82..165	CDD:287501	22/92 (24%)
		PDZ_signaling	206..283	CDD:238492	27/79 (34%)
		PH	720..814	CDD:278594	28/98 (29%)
		PH_CNK_insect-like	720..810	CDD:270135	26/94 (28%)
cnksr1	XP_009291361.1	SAM_CNK1,2,3-suppressor	4..70	CDD:188910	30/68 (44%)
		SAM	4..67	CDD:197735	29/65 (45%)
		CRIC_ras_sig	78..168	CDD:287501	22/93 (24%)
		PDZ_signaling	215..287	CDD:238492	25/72 (35%)
		PH_CNK_mammalian-like	438..552	CDD:269962	34/117 (29%)
		PH	452..548	CDD:278594	28/98 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C62000262
eggNOG	1	0.900				E1_KOG1738
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	266	1.000	Inparanoid score	I2969
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1121556at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000				T596824
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR12844
Phylome	1	0.910		0.800	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
ZFIN	0	0.000	Not matched by this tool.
	9	8.860