Protein Alignment: cnk and LOC100488567

• Sequence 1: NP_001286524.1
• Gene: cnk
• FlyBaseID: FBgn0286070
• Length: 1557
• Species: Drosophila melanogaster
• Sequence 2: XP_017951878.1
• Gene: LOC100488567
• Length: 1024
• Species: Xenopus tropicalis
• Alignment Length: 1245
• Identity: 293/1246 (24%)
• Similarity: 465/1246 (37%)
• Gaps: 374/1246 (30%)

  Fly    20 GLDESMKGYLYEFSKQEIGGRALLNIRPYELENLGMLRIGHQEIVLEAVENLRNFHYHLKNDNLQ 84
            |||:.::.|:..|.:::|.|..||:|...|||.||:.||||||::||||:.|...:|.|:.:||:
 Frog    24 GLDDCLQQYIKNFEREKINGEQLLHITHQELEELGVTRIGHQELILEAVDLLCALNYGLETENLR 88

  Fly    85 FMALHVATAAKNLHRELA----RNHAE---STKIDTRILHDITRTIATLKPLVGSLERTPFRKQE 142
            .::..:..:||||...:.    ..|.:   |.::....|..:...|...|.|:..|:|:||....
 Frog    89 TLSHKLNASAKNLQNFITGRRRSGHYDGRASRRLPNDFLTSVVDLIGAAKNLLAWLDRSPFVSVT 153

  Fly   143 MYREYCGNVLKCGLELATIAHRDRFALQPVPAIRQSAERLENLANFVIQDISDPMVLQPASLNLV 207
            .|.....|:::..|||.||..:|....:....|....:.|..:.:.:|...||.:|.|.|.|.:|
 Frog   154 EYSLLKNNIVQLCLELTTIVQQDCTVYETENKILHVCKTLSGICDHIISLSSDSLVSQSAHLEVV 218

  Fly   208 TLKK-RESE-LGFNIESSYNGIHRVTDIKYNSPAHNSGKIEDGDEIVQINYQTVVGWQHRTVLEH 270
            .|.. ..|| ||..|:|:|:|:|.:|....||||....||..|||::|:|:|||||||.:.::..
 Frog   219 HLTNIMPSEGLGMYIKSTYDGLHVITGTTENSPADQCKKIHAGDEVIQVNHQTVVGWQLKNLVNA 283

  Fly   271 LREALPDVVLTVKKRPKHTKMFGQIYMQPYRLPSKKRNMAARW--AAQMP----SPRAAFLTLDT 329
            |||....|:||:||||::|..         ..|:..:|:  ||  .|..|    ||.:...|
 Frog   284 LREDPNGVILTLKKRPQNTLA---------SAPALLKNV--RWKPLALQPLIPTSPTSGNTT--- 334

  Fly   330 EQLATGGTGSAVPDPSKSLSSEKREVLTKANPVSSASDSDSSCSDIPTPTDPKLAAREIRLYYPK 394
               .||..|.:    ||..||...:|.. .:|||.                         ||.|:
 Frog   335 ---PTGTIGMS----SKVDSSNLHDVFI-LSPVSG-------------------------LYGPR 366

  Fly   395 PRALLQRRNTICGCEYLSLKNSDLVVPSWHERKPGIGSPTNCDPGSPSIRDKSISFGYGLEMAAR 459
            ...      .|..|:.::              |.|:|........|||         |.||
 Frog   367 DEI------GIVSCDDIN--------------KYGVGKSGMKGSESPS---------YYLE---- 398

  Fly   460 PTTCIGIAGDTSTDKARRMFHEARKLKQLTEDSQREFLVDRYKPGVSKVVRFDAKEDYVMKNEKF 524
                                ||:.|...|.|....: :...|:.|.|..||         :.||.
 Frog   399 --------------------HESGKYYTLIEGEGHQ-VGSEYERGRSTGVR---------RREKT 433

  Fly   525 ICNVE----------NTILETFEPIPFADEGDEDALETLRNCKTENAEELLEAINLATKGQDLPL 579
            ..:.:          :.:.|:.||..:..:.:...|..|       :::.:..|      |:.|:
 Frog   434 PTHGDLRPVSMPTEYSWLGESKEPNMYKRDSENSLLRYL-------SDDKILVI------QEEPV 485

  Fly   580 AEAINMPLLQQGRRGR-LDKSHSTPAYDNSGEESDTPPAIEPRKEFLLVTPPAPPPRPRKQREMT 643
            .:..|.  ...|||.| ..|:..:|:|..|.....:...::|.::.:|.
 Frog   486 TQKDNK--RDTGRRSRKKGKNTGSPSYPISPSMLTSTGRLDPAQQDVLT---------------- 532

  Fly   644 PPAVPPPPPKPASMQPASSITSISIPVPVPVPAAVDPSEISELHTPS-KSRTLTLKKKHSLM-AK 706
                            .|...|.::|:            ....|:.| :.||....|..||. ..
 Frog   533 ----------------FSLAESNTVPL------------YHSFHSASLRVRTKKRSKGSSLTGGS 569

  Fly   707 RRNTNLKLLGTGDIQGHLYRRKKNHRG--VTYWARIYFVMLDTILYGFRSKQSTSASLVIFLPGF 769
            ||..:.|.||.||.:|.|: :||:.:|  ...|.:.:|::.|:.||.:.::....|...|.||.|
 Frog   570 RRRISCKDLGHGDCEGWLW-KKKDAKGYFTQKWKKYWFILKDSSLYWYTNQNDEKAEGFISLPEF 633

  Fly   770 TVSLAKEVHSKPHAFKVYH-TAKSFYFAAESLDALNQWVDFLRQASLKVPPSTGSKGGGDAKDLY 833
            .:..|.|...| ||||..| ..|||:||.:.|:.:|:|::.|..|::...|........:| |.:
 Frog   634 RIDRAIECRRK-HAFKACHPKIKSFFFATDCLEEMNRWMNRLGLAAIGYTPDEKDTRPNEA-DYW 696

  Fly   834 SENDSSGEECDALVIQNLSTPSPQGNKESMSMSMTLSGGTPP---SSAPI---KHERGYL----- 887
            ||:|                      ::.:..||||....|.   ||:|.   ||.|.:.
 Frog   697 SESD----------------------QDDIDGSMTLRQEAPSTVNSSSPFPEPKHGRHFSSESTY 739

  Fly   888 ------DSFRKFTNTFKSSAAKPSSDIPVPTEQYRSYR------KVPGGSFGIQIGANTPGYHDP 940
                  ||.:..|.:..||..:||         ||..|      :.|..|.|:......|
 Frog   740 SHSSAEDSRQDATGSTHSSGCRPS---------YRERRSWQDLIETPLTSSGLHFLQTVP----- 790

  Fly   941 AMPPTQIPPLVGPKLSRSSSRSSVVSGTESAVSLSASILGPPASPAPTPTPTAT-PTSLQHQSSE 1004
                              |....||..|               ..:|.....|| |...:|.:..
 Frog   791 ------------------SDGEYVVGHT---------------GMSPEQRRQATLPVQRRHNNER 822

  Fly  1005 ESP-----------SQSQSQSPSSKSSLKKAPFNFLHASNPNLVEFDFHTSKTLLPKMSVGNTLD 1058
            :.|           |.:::|...|:|                            ||:........
 Frog   823 DGPFPLTECPRGHTSHARTQKQRSQS----------------------------LPRNRDVRVKS 859

  Fly  1059 HGHNIQGFVTLKDLMLRKQEEEAQEMYNNRVHLGVEKHKHARTESTASQQSAMSSSVTKPLEKLP 1123
            .|.|.:           |.||::::..:.|.|...:|.     ||...::|:     |..|::|.
 Frog   860 RGKNTE-----------KLEEKSEDELSKRTHSNSDKE-----ESKKEKRSS-----TDGLQELY 903

  Fly  1124 K-IQSVSLPKTPDYEISFKPD--------------DESIKRTRT-KEGQKLRDFGYELICG--DE 1170
            | ::..||....:..:|.|.:              :|.:.|.|. |...|.::....:|..  ::
 Frog   904 KTLEQASLSAFGEQRLSTKQEFRRSFIKRCNDPIMNEKLHRIRVLKSTVKAKEGDLAIINSLLED 968

  Fly  1171 PSTSSISRQE 1180
            |..||...:|
 Frog   969 PQLSSKKLKE 978

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cnk	NP_001286524.1	SAM_CNK1,2,3-suppressor	6..74	CDD:188910	26/54 (48%)
		SAM	7..74	CDD:197735	26/54 (48%)
		CRIC_ras_sig	82..165	CDD:287501	23/90 (26%)
		PDZ_signaling	206..283	CDD:238492	36/79 (46%)
		PH	720..814	CDD:278594	33/97 (34%)
		PH_CNK_insect-like	720..810	CDD:270135	31/93 (33%)
LOC100488567	XP_017951878.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1121556at2759
OrthoFinder	1	1.000				FOG0000782
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010