Protein Alignment Amy-d and Amy1

DIOPT Version :10

• Sequence 1: NP_523768.1
• Gene: Amy-d / 36932
• FlyBaseID: FBgn0000078
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_031472.2
• Gene: Amy1 / 11722
• MGIID: 88019
• Length: 511
• Species: Mus musculus
• Alignment Length: 512
• Identity: 278/512 - (54%)
• Similarity: 349/512 - (68%)
• Gaps: 24/512 - (4%)

  Fly     5 KSIVCLSLLAVANAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGYAGVQVSPVNENAV- 68
            |..:.|||:....||:|.:...||:.:||||||:|.|||.|||.:|.|||:|||||||.|||.|
Mouse     2 KFFLLLSLIGFCWAQYDPHTQYGRTAIVHLFEWRWVDIAKECERYLAPNGFAGVQVSPPNENIVV 66

  Fly    69 -KDSRPWWERYQPISYKLETRSGNEEQFASMVKRCNAVGVRTYVDVVFNHM---AADGGTYGTGG 129
             ..||||||||||||||:.:|||||::|..||.|||.||||.|||.|.|||   .|..|...|.|
Mouse    67 HSPSRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAQAGQSSTCG 131

  Fly   130 STASPSSKSYPGVPYSSLDFNP-TC-----AISNYNDANEVRNCELVGLRDLNQGNSYVQDKVVE 188
            |..:|:::.:||||||..|||. .|     .|.||.||.:||:|.|.||.||.....||:.||.:
Mouse   132 SYFNPNNRDFPGVPYSGFDFNDGKCRTASGGIENYQDAAQVRDCRLSGLLDLALEKDYVRTKVAD 196

  Fly   189 FLDHLIDLGVAGFRVDAAKHMWPADLAVIYGRLKNLNTDHGFASGSKAYIVQEVIDMGGEAISKS 253
            :::||||:||||||:||:|||||.|:..|..:|.|||| ..|:.||:.:|.|||||:||||:|.:
Mouse   197 YMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNT-KWFSQGSRPFIFQEVIDLGGEAVSSN 260

  Fly   254 EYTGLGAITEFRHSDSIGKVFRGKD--QLQYLTNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGA 316
            ||.|.|.:|||::...:|||.|..|  ::.||.|||..||...|||:||||||||||||||||||
Mouse   261 EYFGNGRVTEFKYGAKLGKVMRKWDGEKMSYLKNWGEGWGLMPSDRALVFVDNHDNQRGHGAGGA 325

  Fly   317 DVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQ---------GPPTTDGHNIASPIFNS 372
            .:||:...:.||||..||||||:|..|||||:.:....|         |||..:|......| |.
Mouse   326 SILTFWDARLYKMAVGFMLAHPYGFTRVMSSYYWPRNFQNGKDVNDWVGPPNNNGKTKEVSI-NP 389

  Fly   373 DNSCSGGWVCEHRWRQIYNMVAFRNAVGLDEIQNWWDSGSNQISFSRGSRGFVAFNNDNYDLNSS 437
            |::|...|:||||||||.|||||||.|......||||:.|||::|.||::||:.||||::.|:.:
Mouse   390 DSTCGNDWICEHRWRQIRNMVAFRNVVNGQPFANWWDNDSNQVAFGRGNKGFIVFNNDDWALSET 454

  Fly   438 LQTGLPAGTYCDVISGSKSGSSCTGKTVTVGSDGRASIYIGSSEDDGVLAIHVNAKL 494
            ||||||||||||||||.|...:|||..|.||:||:|...|.:|.:|..:|||..:|:
Mouse   455 LQTGLPAGTYCDVISGDKVDGNCTGIKVYVGNDGKAHFSISNSAEDPFIAIHAESKI 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amy-d	NP_523768.1	AmyAc_bac_euk_AmyA	28..399	CDD:200456	219/392 (56%)
		Aamy_C	405..493	CDD:214749	49/87 (56%)
Amy1	NP_031472.2	AmyAc_bac_euk_AmyA	25..416	CDD:200456	219/392 (56%)
		Aamy_C	422..510	CDD:214749	49/87 (56%)