Protein Alignment Mov10 and setx

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: XP_068072062.1
• Gene: setx / 562474
• ZFINID: ZDB-GENE-070402-1
• Length: 2396
• Species: Danio rerio
• Alignment Length: 800
• Identity: 175/800 - (21%)
• Similarity: 295/800 - (36%)
• Gaps: 198/800 - (24%)

  Fly    38 LEFYNVCSVMQTLLTIDDLSNMELYAQLIQSDVPVQRVSKLTYKITFKSTPVNAEDFVA---PNL 99
            ||::|....:..:...::::|..|....::..:.||.:.        .|....:..|:|   ...
Zfish  1531 LEYFNTLYPLLLINAFEEMANEWLKEGRVKLYLKVQGIE--------YSNRTASASFIAGLSQEC 1587

  Fly   100 DQVVLVPKASLLASPLPKQLVLALLP----------------HPHEDLEPGDPMLRHVASVDKVS 148
            |...:.||..        .|||..||                |||........:|..........
Zfish  1588 DVKQIYPKED--------DLVLLWLPDNTGAYAQDEPNFHDLHPHFGYVSRSNVLNRTPGSRSTL 1644

  Fly   149 STTVHVRFSRKHKAVLSGQRFYAIIRSRRLTIRYMYRALNLLQESPLVRRYLFPFPSWLTQLVDN 213
            :.|:.   :|.:.:.::.|.....:....::|...:|||.||:..|::|..|.|..|:.|..:|.
Zfish  1645 NLTIQ---TRGNVSSVNSQPVLCEVVGSLISIFREFRALCLLRNGPMLRPLLAPHVSFFTHSLDG 1706

  Fly   214 SQIKVCCDGHLPNWMQGRPQEPATPTSLSLLNSTIYSNAEQLEAVQRIVAGPSTQGPYILFGPPG 278
            ..     |...|.:  .|.|..|....:::::..                 ..|....::.||||
Zfish  1707 PS-----DLDAPEF--NRDQARAIACGIAMIHRK-----------------QKTPKFLLIHGPPG 1747

  Fly   279 TGKTTTI--------------VEAILQLRLQQPQSRILVTAGSNSACDTIALKL----------- 318
            |||:.||              ...:..|..:..::|:|:.|.||:|.|::..|:
Zfish  1748 TGKSKTIGGLLYKLLSSATNSSATVGNLHSKSRRTRVLLCAPSNAAIDSLMKKVILIFKEKCRNI 1812

  Fly   319 ------C-----------------------------------EYIESNIRLQEHFAQQKLPEPDH 342
                  |                                   :.:||::..::....|.:....|
Zfish  1813 NAPQGNCGDINLVRLGNERTISKSLKPFSLDHQTKARAQRAQQTVESDVHRRKEQLDQMIENLSH 1877

  Fly   343 QLIRVYSRSIYEKGFASVPSLLLK-NSNCSKSIYD------HIKASRIVKYGIIVATLCTVARLV 400
            |..:....|...|.........|| ....|:.|.:      ..:|..:....:|..||.|...:|
Zfish  1878 QCAKTQKNSTEFKNLLEQKKQFLKEREGLSRQIKECRGRRQESQALVLQNAHVICCTLSTSGSIV 1942

  Fly   401 TDTLGR---YNFFTHIFIDEAGASTEPEALIGIMGIKQTADC-HVILSGDHKQLGAVIKSNRAAS 461
            .:...|   :..|:.:.||||..:.|.|.||.::     ..| .|||.||..||...:.|.:|..
Zfish  1943 LENAFRRLGHEPFSCVIIDEASQAKETETLIPML-----YRCPSVILVGDPNQLPPTVVSQKAKE 2002

  Fly   462 LGLSRSLMERLLQSDCYKSDENGNYDRNRQMRLCRNYRSHPQIVRLFNELYYNGELKAQ-----A 521
            .|..:|||.||    | ||....|......:.|...||.||.|....::..||..||..     .
Zfish  2003 FGFDQSLMARL----C-KSLHPSNSKLPPILLLSMQYRMHPDICEFPSKYIYNSALKNDWQGQCR 2062

  Fly   522 PAMDVNLAANWSVLTNPQFPI-------------------IFQATHGVTNREQNSTSSYNNLEAE 567
            ...::...:.:.:|.:...|.                   :|....|...:|::  |..|:.|..
Zfish  2063 QEQEIRTVSEFRLLRSLSGPCVCETAQKRCSLSWPFKPYKVFDVMDGRETKERD--SFINHKEVS 2125

  Fly   568 VICWYVKRLINDRVVGQEDVGIVAPYTAQGKLVTKLLQSKGYP---NVEVGSVETYQGREKTIII 629
            ::...:|.|..::.|   .||::.||.||...:...:::.|..   .|||.:|:.:||||...||
Zfish  2126 LVGLLLKLLCKEQAV---RVGVITPYNAQKHRILDAIKTSGINKQLQVEVDTVDGFQGREMDCII 2187

  Fly   630 ASLVKSFTNM---GFMCNPRRVNVLLSRAKALLILVGNPVTLRHHSDFKFVINECKKHGTYLLKK 691
            .|.|::.:.|   ||:.|.:|:||.::|||..|.::|:..|||..||:..:|
Zfish  2188 VSCVRASSEMGSIGFVGNRQRMNVTITRAKFSLFILGHLRTLREQSDWGALI------------- 2239

  Fly   692 RDSGQRPHILIKADESNEES 711
            .|:|:| ..:|...:.|.||
Zfish  2240 EDAGRR-ECIINTMQKNFES 2258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	68/324 (21%)
		DNA2	<388..684	CDD:440729	93/329 (28%)
setx	XP_068072062.1	SEN1_N	37..>322	CDD:432746
		TIGR00376	<1713..2245	CDD:273041	131/578 (23%)
		DEXXQc_SETX	1715..2035	CDD:438712	71/348 (20%)