Protein Alignment Mov10 and Setx

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: XP_006233948.1
• Gene: Setx / 362096
• RGDID: 1565575
• Length: 2702
• Species: Rattus norvegicus
• Alignment Length: 886
• Identity: 192/886 - (21%)
• Similarity: 320/886 - (36%)
• Gaps: 257/886 - (29%)

  Fly    11 NEMIEANTNQD-LSANNSVFGDFMKTKRLEFYNVCSVMQTLLTIDDLSNMELYAQLIQSDVPVQR 74
            |....|.::.| |..:.|:|..|:|......|      |..|..|.........|.|...|||:.
  Rat  1661 NRPASAASSVDILLPSQSIFDTFIKEVLKWKY------QMFLNFDKCGAPTSLCQSISRPVPVRF 1719

  Fly    75 VSKLTYKITFKSTPV-NAEDFVA------PNLDQVVLVPKASLLA--------------SPLPKQ 118
            .....|...|....: ||.:.||      ||.:....:......|              |.|.||
  Rat  1720 QDCAEYFNVFLPLIILNAFETVAQEWLNSPNKENFYQLHLRKFPADYKKYWEFLIYLEESELAKQ 1784

  Fly   119 LVLALLPHPHED----LEPGDPMLRHVASVDKVSSTTVHVRFSRKHKAVLSG------------- 166
            |      ||.|:    |.|....:...:..|:......:|...|:...:.||
  Rat  1785 L------HPKENDLVFLVPEKKYMDRHSVQDRSHYYCGYVHKFRRTSVMRSGKTECSLCIQTQDN 1843

  Fly   167 ------QRFYAIIRSRRLTIRYMYRALNLLQ-ESPLVRRYLFPFPSWLTQLVDNSQIKVCCDGHL 224
                  :....|:.|..:|.:...:|::||. .:.|.|..|.|.|
  Rat  1844 MPASVKELTKCIVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNP-------------------- 1888

  Fly   225 PNWMQGRPQEPATPTSLSLLNSTIYSNAEQLEAVQRIVA----GPSTQGPYILFGPPGTGKTTTI 285
               |....::..|.||..::......|.:|.:|::...|    .||.....::.|||||||:.||
  Rat  1889 ---MDFCTKDLLTTTSERIIAYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTI 1950

  Fly   286 VEAILQLRLQQ--------------PQSRILVTAGSNSACDTIALKL-----------------C 319
            |..:.:|..:.              .|:|:||.|.||:|.|.:..|:                 |
  Rat  1951 VGLLYRLLTESQRKGHSDENFNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNC 2015

  Fly   320 EYI-------ESNIRLQ----------EHFAQQKLPEPDHQLIRVYSRSIYEKGFASVPSLLLKN 367
            ..|       |.:|..:          .|..::.||....:::|  .:.|.:   |.:..|..:.
  Rat  2016 GDINLVRLGPEKSINTEVLKFSLDSQVSHRMKKDLPSHIQEMLR--RKEILD---AQLDELSRQR 2075

  Fly   368 SNC-------SKSIYDHI---------KASR---------------IVKYGIIVATLCTVARLVT 401
            :.|       .:.:.:||         .||:               |::..:|..||.|...|:.
  Rat  2076 ALCRGGREMQRQELDEHIVIVSKERQELASKIKEVQGRPQRAQNTIILESHVICCTLSTSGGLLL 2140

  Fly   402 DTLGRYNF---FTHIFIDEAGASTEPEALIGIMGIKQTADCH-VILSGDHKQLGAVIKSNRAASL 462
            ::..|...   |:.:.:||||.|.|.|.|..::     ..|: ::|.||.|||...:.|.:|...
  Rat  2141 ESAFRGQGGVPFSCVIVDEAGQSCEVETLSPLI-----HRCNKLVLVGDPKQLPPTVISMKAQEY 2200

  Fly   463 GLSRSLMERLLQSDCYKSDENGNYD---RNRQMRLCRNYRSHPQIVRLFNELYYNGELKAQAPAM 524
            |..:|:|.|.    |...:||...:   |...::|...||.||.|....:...||..||......
  Rat  2201 GYDQSMMARF----CKLLEENVEQNMIGRLPVLQLTIQYRMHPDICLFPSNYVYNKNLKTNRLTE 2261

  Fly   525 DVNLAANWSVLTNPQFP-IIFQATHGVTNREQNSTSSYNNLEAEVICWYVKRLIND--RVVGQED 586
            .:..::.|     |..| ::|....|   .||....||.|::...:...:.:||.:  :.:...:
  Rat  2262 TIRCSSEW-----PFQPYLVFDVGDG---SEQRDNDSYINVQEIKLVMEIIKLIKEKRKDISFRN 2318

  Fly   587 VGIVAPYTAQGKLVTK----------LLQ------------------------------------ 605
            :||:..|.||..::.|          |||
  Rat  2319 IGIITHYKAQKTMIQKDLEKEFDKKGLLQPIMMGESRQQDSEASKQQQKSSECMHASDELDSSTV 2383

  Fly   606 -SKGYPNV----------EVGSVETYQGREKTIIIASLVKSFT---NMGFMCNPRRVNVLLSRAK 656
             ..|..::          ||.:|:.:|||:|..||.:.|::..   ::||:.:.:|:||.::|||
  Rat  2384 TQSGISSLENGATHTGPAEVDTVDAFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITRAK 2448

  Fly   657 ALLILVGNPVTLRHHSDFKFVINECKKHGTYLLKKRDSGQR 697
            ..|.::|:..||..:..:..:|.:.:|.|. ::|..|...|
  Rat  2449 YSLFILGHLRTLMENQHWYELIQDAQKRGA-IIKTCDPNYR 2488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	77/337 (23%)
		DNA2	<388..684	CDD:440729	87/365 (24%)
Setx	XP_006233948.1	DEXXQc_SETX	1911..2236	CDD:438712	77/338 (23%)
		AAA_12	2202..2456	CDD:463780	58/265 (22%)