Protein Alignment Mov10 and Dna2

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_727386.1
• Gene: Dna2 / 31934
• FlyBaseID: FBgn0288690
• Length: 1100
• Species: Drosophila melanogaster
• Alignment Length: 626
• Identity: 141/626 - (22%)
• Similarity: 240/626 - (38%)
• Gaps: 177/626 - (28%)

  Fly   147 VSSTTVHVRFSRKHKAVLSGQRFYAIIRSRRLTIRYMYRALNLLQESPLVRRYLFPFPSWLTQLV 211
            :|||:        ..||.:|  |...|.:|||.:|.         |..|.:||     |..|.::
  Fly   537 ISSTS--------RLAVAAG--FIVSIEARRLDLRL---------ERDLSQRY-----SEETFII 577

  Fly   212 DNSQIKVCCDGHLPNW-----------------MQGRP--QEPATPTSLSLLNSTIYSNAEQLEA 257
            |....:.....:..|.                 :..:|  |....|..:....:.|..|   |..
  Fly   578 DKHDSQSFATFNFTNLGMLLSEGERFQELRDIIVAKKPPEQHKVLPKIILTKGAPILLN---LNK 639

  Fly   258 VQRIVA--GPSTQGPYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSACDTIALKLCE 320
            ||:..|  ..:|....::.|.||||||.|:|..:..|.|.  ...:|:||.::||.|.:.::|..
  Fly   640 VQQNAALRALTTSSHLLIKGLPGTGKTQTLVALVRLLHLL--GKSVLITAQTHSAVDNLIMRLLP 702

  Fly   321 Y------IESNIRLQ---EHFAQQKLPEPDHQLIRVYSRSIYEKGFASVPSLLLKNSNCSKSIYD 376
            :      :.|..|:.   |..::::|.: |.:.:....:::.:.....|..|     .|...::.
  Fly   703 FGLPMMRLGSGSRIHKQLEEISEERLTK-DCKTVEELEKALGQPSIVGVTCL-----GCGHPLFQ 761

  Fly   377 HIKASRIVKYGIIVATLCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEALIGIMGIKQTADCHV 441
            ..:                              |.:..:|||....:|..|..::...:     .
  Fly   762 RRQ------------------------------FDYCIVDEATQVLQPTVLRPLIHCSK-----F 791

  Fly   442 ILSGDHKQLGAVIKSNRAASLGLSRSLMERLLQSDCYKSDENGNYDRNRQMRLCRNYRSHPQIVR 506
            :|.||.:||..:::|..|...|...:|.:||   |..|:          ...|...||.:..|.|
  Fly   792 VLVGDPEQLPPIVRSKEARQRGADETLFQRL---DSEKA----------TAVLSLQYRMNKTITR 843

  Fly   507 LFNELYYNGELKAQAPAMD--------VNLAANW---SVLTNPQFPIIFQATHGVTNR------- 553
            |.|||.|.|:||..:..:.        :|.|..|   ::.|:.:..:....|.....|
  Fly   844 LANELTYGGDLKCASDEVSGARFEVELLNEAPRWVQRALTTHLEQAVTLINTGDCLERCQEFVYA 908

  Fly   554 -----------EQN---------------STSSYNN-LEAEVICWYVKRLINDRVVGQE--DVGI 589
                       ||:               ..|.|.| .||.::...::.|:..   |.|  .:|:
  Fly   909 SQRLVDTCSSIEQSFSEDKDEIRKLTSKKRVSKYTNYCEAGIVMHLLRYLLKS---GYEASRIGV 970

  Fly   590 VAPYTAQGKLVTKLLQSKGYPNVEVGSVETYQGREKTIIIASLVKS---FTNM------GFMCNP 645
            :|||.||.:|..| |.||...::|..:|:.:|||:|.:||.|..|:   |::|      ..:.:.
  Fly   971 IAPYRAQVELFKK-LASKLDTDLECNTVDQFQGRDKNLIIYSCSKTGGDFSDMERSREAEILEDQ 1034

  Fly   646 RRVNVLLSRAKALLILVGNPVTLRHHSD----FKFVINECK 682
            ||:.|.::|||..|||:|:...|..:..    ||.:.:.|:
  Fly  1035 RRLTVAITRAKNKLILLGDIKCLEQYGPFRQLFKHIPDRCR 1075

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	52/258 (20%)
		DNA2	<388..684	CDD:440729	85/355 (24%)
Dna2	NP_727386.1	DNA2_N-like	153..378	CDD:411722
		DEXXQc_DNA2	636..836	CDD:350799	52/258 (20%)
		AAA_12	815..1055	CDD:463780	67/256 (26%)