Protein Alignment Mov10 and hrr1

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_588411.2
• Gene: hrr1 / 2539248
• PomBaseID: SPCC1739.03
• Length: 999
• Species: Schizosaccharomyces pombe
• Alignment Length: 920
• Identity: 186/920 - (20%)
• Similarity: 301/920 - (32%)
• Gaps: 366/920 - (39%)

  Fly     2 RELPYYPPSNEMIEANTNQDLSANNSVFGDFMKTKRLEFYNVCSVMQTLLTIDDLSNMELYAQLI 66
            ||||..|...|:  .:.:.:|.:|| ::|.:   |..|.|                 :.::.:|:
pombe   131 RELPSIPTLEEL--TSKSVELPSNN-IYGGY---KSFEDY-----------------LSIHYRLL 172

  Fly    67 QSD-VPVQRVSKLTYK-----ITFKSTPVN----------AEDFVAPNLDQVVLVPK-------- 107
            :.| |...|.|.|.||     ||..|..|.          :...:|..|...|...|
pombe   173 REDAVSPLRESVLRYKVNPNYITGSSLAVYDHVRIDGYTISSSVIAAKLSFSVRAKKKIKWATSR 237

  Fly   108 --------------------ASLLASPLPKQLVLALLPHPHE----------DLEPGDPML---- 138
                                .::.|.||.     .|..||||          .|:|.:..:
pombe   238 RLISGSLVLLSNDDFQTFRIGTVCARPLS-----GLNKHPHEIDVKFEDISISLDPREEYVMIEA 297

  Fly   139 --------RHV-ASVDKVSSTTVHVRFSRKHKAVLSGQRFYAIIRSRRLTIRYMYRALNLLQESP 194
                    :|| .|:.::|::|..::....|            .:|.:.|.::       :|.:|
pombe   298 TSGYWEAYKHVLRSLQRLSASTFPMKDYLVH------------CKSNQETAKH-------IQNNP 343

  Fly   195 LVRRYLFPFPSWLTQLVDNSQIKVCCDGHLPNWMQGRPQEPATPTSLSLLNSTIYSNAEQLEAVQ 259
            .:|         :..::.|:..|:.           ...||..|....|       ::.||:|.|
pombe   344 RIR---------INSILKNNSQKIV-----------NALEPFGPGEYIL-------DSSQLKAYQ 381

  Fly   260 RIVAGPSTQGPYILFGPPGTGKTTTIVEAILQLRLQQPQSR---ILVTAGSNSACDTIALKLCEY 321
            .::    |:...|:.|||||||:...::||..| |:...|.   |||...:|.|.|.|.::|...
pombe   382 SML----TKRLSIIQGPPGTGKSFVTLKAIETL-LENTHSHVLPILVACQTNHAVDQILIRLLHQ 441

  Fly   322 IESNIRLQEHFAQ---------QKLPEPDHQLIRVYSR--------------------------- 350
            ..|.:||......         ||.....|.....|:.
pombe   442 GASVMRLGSRTKDPEIAAVTIFQKAKHTKHSFKAAYNEIRHKKQRLIKQITNIMHNFNLEFVTLS 506

  Fly   351 SIYEKGFASVPSL--LLKNSNCSKSIYDH--------------------IKASRIV--------- 384
            .::.||..:...|  |..|:....|:.::                    |..|.|.
pombe   507 YLHSKGIITTSQLESLRNNTEWISSVAENGEKTEEELISIWLGDAKVELITPSEITDGFEEELQI 571

  Fly   385 --------------------------------KYGIIVATLCTVARLVTDTL------------- 404
                                            ||  :.:.|.|:.....|||
pombe   572 DPEKLEEIQKEAEDSGALMEEELRGKFINLRCKY--LFSKLTTLHEKEIDTLLTIPNIWDIPEYS 634

  Fly   405 ---------------------GRYNFFTHIFIDEAGASTEPEALI----GIMG------------ 432
                                 ..|.|:..:..:..|.|.:..|::    .::|
pombe   635 RGIIYCRWLESAYAAAEKELNRLYRFYLKVDRERIGFSNKRAAILLRGANVIGMTTTGLNKYRDI 699

  Fly   433 ----------IKQTADC--------------HVILSGDHKQL--GAVIKSNRAASLGLSRSLMER 471
                      |::.||.              .::|.||||||  |....:.|.....||.|:.||
pombe   700 LERINPKICFIEEAADVLEGPIIPAVFPSLEQLVLIGDHKQLRPGCSTYALRQDPFNLSISMFER 764

  Fly   472 LLQSDCYKSDENGNYDRNRQMRLCRNYRSHPQIVRLFNELYYNGELKAQAPAMDVNLAANWSVLT 536
            |:::|.            ...||....|.||||.||.:.:|.:        ..|..:...|
pombe   765 LVENDM------------EYTRLTMQRRMHPQIRRLVSSVYED--------LSDYEITKYW---- 805

  Fly   537 NPQFPII-----FQATHGVTNREQNSTSSYNNLEAEVICWYVKRLINDRVVGQEDVGIVAPYTAQ 596
             |..|.:     |..||..........|..|..||:::..:...|||:.|..|: :..:..|.||
pombe   806 -PSIPGMGEIRRFFLTHSRIEDNDGFASKINLFEAQMLVQFAVYLINNGVEPQK-ITCLTFYAAQ 868

  Fly   597 GKLVTKLL-----QSKGYPNVEVGSVETYQGREKTIIIASLVKS--FTNMGFMCNPRRVNVLLSR 654
            ..|:.:||     :.|.:  ::|.:|:.|||.|..:::.|||::  .|.:||:.:|.||.|.|||
pombe   869 KDLIERLLSESLNREKHF--IKVATVDGYQGEENDVVLLSLVRNNDRTEVGFLSSPHRVCVSLSR 931

  Fly   655 AKALLILVGN 664
            |:..|.:.||
pombe   932 ARRGLFIFGN 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	76/425 (18%)
		DNA2	<388..684	CDD:440729	86/365 (24%)
hrr1	NP_588411.2	DEAD-like_helicase_N	372..>469	CDD:475120	32/108 (30%)
		DEAD-like_helicase_N	<682..779	CDD:475120	22/108 (20%)
		SF1_C_Upf1	781..959	CDD:350195	53/177 (30%)