Protein Alignment Mov10 and Upf1

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: XP_322028.5
• Gene: Upf1 / 1282033
• VectorBaseID: AGAMI1_014598
• Length: 1161
• Species: Anopheles gambiae
• Alignment Length: 650
• Identity: 170/650 - (26%)
• Similarity: 264/650 - (40%)
• Gaps: 145/650 - (22%)

  Fly   134 GDPM-LRHVASVDKVSSTTVHV-------------RFSRKHKAVLSGQRFYAIIRSRRLTIRYMY 184
            ||.: ||:|..:.|..|...||             .....|:|        .|.|:...::.:::
Mosquito   344 GDELKLRYVGELHKPWSCIGHVIKVPDNYGDDVGLELKHNHQA--------PIERTSNFSVDFIW 400

  Fly   185 RALNLLQESPLVRRYLFPFPSWLTQLVDNSQIKVCCDG--------HLPNWMQGRPQEPATPTSL 241
            :..:..:....:|::.....|....:.......|..||        :||.....    |..|.
Mosquito   401 KGTSFERMQQALRKFAMDAKSVSNYIYARLLGNVRADGAEEVLFRLNLPKHFSA----PNLPD-- 459

  Fly   242 SLLNSTIYSNAEQLEAVQRIVAGPSTQGPYILFGPPGTGKTTTIVEAILQL-RLQQPQSRILVTA 305
                    .|..|:.||:..:..|.:    ::.||||||||.|....:.|| ||.  ...|||.|
Mosquito   460 --------LNRSQVYAVRHALQRPLS----LIQGPPGTGKTVTSATIVYQLARLN--SGPILVCA 510

  Fly   306 GSNSACDTIALKLCEYIESNIRLQEHFAQQKLPEPDHQLIRVYSRSIYEKGFASVPSLL------ 364
            .||:|.|.:.                   :|:...:.:::||.:||  .:...|..|.|
Mosquito   511 PSNTAVDQLT-------------------EKIHRTNLKVVRVCARS--REAIDSPVSFLALHNQI 554

  Fly   365 --------------LKNSNCSKSIYDHIKASRIVKYG---IIVAT---LCTVARLVTDTLGRYNF 409
                          ||:.....|:.|..:...:.|..   ::.|.   .||........|.|..
Mosquito   555 RNMAQNSELKKLQQLKDETGELSLSDERRYRSLKKQAERELLEAADVICCTCVGAGDLRLQRIK- 618

  Fly   410 FTHIFIDEAGASTEPEALIG-IMGIKQTADCHVILSGDHKQLGAVIKSNRAASLGLSRSLMERLL 473
            |..|.|||:..|||||.::. ::|.||     :||.|||.|||.|:...:||..|||:||.|||:
Mosquito   619 FNSILIDESMQSTEPECMVPVVLGAKQ-----LILVGDHCQLGPVVMCKKAAKAGLSQSLFERLV 678

  Fly   474 QSDCYKSDENGNYDRNRQMRLCRNYRSHPQIVRLFNELYYNGELKAQAPAMDVNLAAN--WSVLT 536
            ....            |..||...||.||::.:..:..:|.|.|:....|.:..|..:  |   .
Mosquito   679 ALGI------------RPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCADERKLKVDFPW---P 728

  Fly   537 NPQFPIIFQATHGVTNREQNSTSSYNNLEAEVICWYVKRLINDRVVGQEDVGIVAPYTAQGKLVT 601
            :|..|:.|..|.|......:.||..|..||..:.....|.:. ..:..:.:||:.||..|...:.
Mosquito   729 SPDCPMFFLVTQGQEEIAGSGTSYLNRTEASNVEKITTRFLK-AGIKPDQIGIITPYEGQRAYLV 792

  Fly   602 KLLQ------SKGYPNVEVGSVETYQGREKTIIIASLVKS--FTNMGFMCNPRRVNVLLSRAKAL 658
            :.:|      ||.|..:|:.||:.:|||||.|||.|.|::  ...:||:.:|||:||.|:|||..
Mosquito   793 QYMQYQGSLHSKLYQEIEIASVDAFQGREKDIIIMSCVRANEHQGIGFLNDPRRLNVALTRAKYG 857

  Fly   659 LILVGNPVTLRHHSDFKFVINECKKHGTYLLKKRDSGQRPHILIKADESNEESSSEPEDEDDKLI 723
            :|:||||..|.....:..::|      .|..||        :|::...:|.:.|.....:..|:|
Mosquito   858 IIIVGNPKVLAKQELWNHLLN------FYKDKK--------VLVEGSLNNLKESMIQFTKPKKII 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	79/275 (29%)
		DNA2	<388..684	CDD:440729	101/309 (33%)
Upf1	XP_322028.5	None