Protein Alignment Mov10 and setx

DIOPT Version :10

• Sequence 1: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: XP_002936221.1
• Gene: setx / 100145435
• XenbaseID: XB-GENE-966858
• Length: 2535
• Species: Xenopus tropicalis
• Alignment Length: 824
• Identity: 191/824 - (23%)
• Similarity: 331/824 - (40%)
• Gaps: 224/824 - (27%)

  Fly    39 EFYNVCSVMQTLLTIDDLS----------NMELYAQLIQSDVPVQRVSKLTYKITFKSTPVNAED 93
            |::||...:..|.|.:.|:          :.:|....:|:..|...|::..:::.|:.
 Frog  1644 EYFNVFFPLMLLNTFESLAQEWSVKQKAIHTDLCKLHLQNFCPDGLVNRGEFQVWFRD------- 1701

  Fly    94 FVAPNLDQVVLVPKASLLASPLPKQ--LVLALLPHPHEDLEPGDPMLRHVASVDKVSSTTVHVRF 156
                          |.|.....||:  ||...:|.....|. |:.|:.|.|   :|..|....||
 Frog  1702 --------------ADLCMQRHPKEDDLVFLCMPESTPSLS-GEEMVSHGA---RVYHTGYVSRF 1748

  Fly   157 SRKHKAVLSGQRFY-----------------------AIIRSRRLTIRYMYRALNLLQESPLVRR 198
            :|.|:.....:..|                       |:|.| .:|.:..:|||..||.:||.|.
 Frog  1749 NRSHRTQSQEKEQYTLCDLCIHTQGNLSAFRNQQVRCAVIGS-LITTQRQFRALLQLQRNPLFRP 1812

  Fly   199 YLFPFPSWLTQLVDNSQIKVCCDGHLPNWMQGRPQEPATPTSLSLLNSTIYSNAEQLEAVQR--- 260
            .:.|.|:...                       |::.|...|.|..:...| |::|..|:::
 Frog  1813 IILPNPADFI-----------------------PRDNAASESSSFPSLKEY-NSDQRYAIEKAYS 1853

  Fly   261 -IVAGPSTQGPYILFGPPGTGKTTTIVEAILQLRLQQPQS--------------RILVTAGSNSA 310
             :...|......::.|||||||:.|||..:.::.::...|              |:||.|.||:|
 Frog  1854 MVKQHPRLPRICLIHGPPGTGKSKTIVGLLYRILMENGSSTVPVQNLSAKNKRNRVLVCAPSNAA 1918

  Fly   311 CDTIALKL------------------------------------------CEYIESNIRLQEHFA 333
            .|.:..|:                                          |:......|.|:...
 Frog  1919 LDDLMKKIILEFKEKCHNKNTPLGNCGDINLVRLGAEKTISSDVVKFSLDCQVNHRITRAQQDQE 1983

  Fly   334 QQKLPE-PDHQLIRVYSRSIYEK----GFASVPSLLLKNSNCSKSIYDHIKASR----------I 383
            ..|..| .|.:|..:..|...||    ..|.:...:.:.|...:.:.|.:|..|          |
 Frog  1984 LHKRKELLDRRLDELSRRRALEKCNKNTCAPLDEEIARLSKERQLLADSLKLVRRRPQELQRTII 2048

  Fly   384 VKYGIIVATLCTVARLVTDT----LGRYNFFTHIFIDEAGASTEPEALIGIMGIKQTADCH---- 440
            ::..:|..||.|...::.::    ||: ..|:.:.:||||.|.|.|.||.::        |
 Frog  2049 LESHVICCTLSTSGGILLESAFRQLGQ-EPFSCVIVDEAGQSCEVENLIPLL--------HRCSK 2104

  Fly   441 VILSGDHKQLGAVIKSNRAASLGLSRSLMERLLQSDCYKSDENGNYDRNRQMRLCRNYRSHPQIV 505
            ::|.||.:||...:.|.:|..||..:|||.|:    |...|..|.  ::..:.|...||.||.|.
 Frog  2105 LVLVGDPEQLPPTVISMKAEELGYGQSLMSRM----CSFLDSTGT--KSPVLHLTVQYRMHPDIC 2163

  Fly   506 RLFNELYYNGELKAQAPAMDVNLAANWSVLTNPQFP-IIFQATHGVTNREQNSTSSYNNLEAEVI 569
            ...:..:|...||......:|..:::|     |..| ::|....|...:|:.|..  |..|.:|.
 Frog  2164 LFPSHYFYKRMLKTDRATEEVRCSSDW-----PFQPYMVFDVADGFEQKERESFC--NPQEIKVA 2221

  Fly   570 CWYVKRLINDRVVGQE----DVGIVAPYTAQG-KLVTKLLQSKG---YPNVEVGSVETYQGREKT 626
            ...:| ||..|  .:|    ::|::.||.||. :::.:|.::.|   .|. ||.:|:.:|||:|.
 Frog  2222 VALIK-LIKSR--KKEFCFRNIGVITPYRAQKMRIIEELRRAFGNDIRPG-EVDTVDGFQGRQKD 2282

  Fly   627 IIIASLVKSFT---NMGFMCNPRRVNVLLSRAKALLILVGNPVTLRHHSDFKFVINECKKHGTYL 688
            .||.:.|::.:   .:||:.:.:|:||.::|||..|.::|:..||..:.|:..:|.:.::.|. |
 Frog  2283 CIIVTCVRANSTQGGIGFLASRQRLNVTITRAKFSLFILGSLRTLMENKDWNHLIQDAQRRGA-L 2346

  Fly   689 LK------KRDSGQ----RP-------HILIKADESNEESSSEP 715
            :|      :||.|:    :|       |...:.:|..::||:.|
 Frog  2347 IKTREEHYQRDVGKILKLKPVVQRAPIHPNSRPEEKQKDSSAPP 2390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	74/330 (22%)
		DNA2	<388..684	CDD:440729	90/315 (29%)
setx	XP_002936221.1	SEN1_N	38..>347	CDD:432746
		DEXXQc_SETX	1840..2157	CDD:438712	75/332 (23%)
		DNA2	<1946..2343	CDD:440729	106/422 (25%)
		PHA03247	<2365..2534	CDD:223021	6/26 (23%)