back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SmydA-6 and Smyd4

DIOPT Version :9

Sequence 1:	NP_611182.1	Gene:	SmydA-6 / 36917	FlyBaseID:	FBgn0034183	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001096081.1	Gene:	Smyd4 / 319822	MGIID:	2442796	Length:	799	Species:	Mus musculus

Alignment Length:	613	Identity:	117/613 - (19%)
Similarity:	204/613 - (33%)	Gaps:	217/613 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GRFAVALCNVRAGETLLLENPIVVLPLMGER-RCSKCF------NLT--ESFCRKCRLLAL---- 72
            ||..||..::..||.|:.|:..|.:.:.||. |...|.      .:|  :.:|.:|....|
Mouse   244 GRHLVATKDILPGELLVKEDAFVSVLIPGEMPRPHHCLENKWDTRVTSGDLYCHRCLKHTLATVP 308

  Fly    73 CEDCS--DHDERDCKRLA-EMNFSDD------------------QVELLQKKEHTEIQPVLKCL- 115
            |..||  .:..::|.:.| ::..|.:                  ::.||.:.|  ::..|::.|
Mouse   309 CGSCSYAKYCSQECMQQAWDLYHSTECSLGGLLLTLGVFCHVALRMTLLARFE--DVDRVVRMLC 371

  Fly   116 --------LLREHEETLPLYEEMSQMDSQLMTRRG--------------------------TEVW 146
                    .|.|.:..:..::..||.:|:..::.|                          ||
Mouse   372 DEVGSTDTCLPESKNLVKAFDYTSQGESEEKSKIGEPPIPGCNVNGKYGSNYNAIFSLLPHTE-- 434

  Fly   147 KNYQEHAF-TPLDYGGVLAQLRGAADEDLVQGLLGILDINAYEIRAPEV--------------GG 196
            |:..||.| ..:....:..||:  ||           .:.|..:::|::              |.
Mouse   435 KHSPEHRFICAISVSALCRQLK--AD-----------SVQAQTLKSPKLKAVTPGLCADLTVWGA 486

  Fly   197 AM------------------------------------RGLYRRAGLFAHSCTPNLVISIDDEQR 225
            ||                                    .|::....|..|||.||..:|.....
Mouse   487 AMLRHMLQLQCNAQAITSICHTGSNESIITNSRQIRLATGIFPVVSLLNHSCRPNTSVSFTGTV- 550

  Fly   226 IKVYANRFIAAGEILYNCY--TNVLLGTEERRKILKVGKCFDCSCPRCQDPT---ELGTHMSSFI 285
            ..|.|.:.||.|:.:.:||  ....:|..||::.|.....|||.|..|...|   .......:|.
Mouse   551 ATVRAAQRIAKGQEILHCYGPHESRMGVAERQQRLSSQYFFDCRCGACHAETLRAAAAPRWEAFC 615

  Fly   286 CSQCSCVDGYIVRQPDTGIWQCLLNPEHTLKQEFVSNMLERAKEEIFHARDDIYRQELLLAKLSR 350
            |..|..:      .....:..|        ..|..:|.:.|               :.|:::|.
Mouse   616 CKTCRAL------MQGNDVLSC--------SNESCTNSVSR---------------DQLVSRLQ- 650

  Fly   351 LLHRNHFLMLDLKQNIASILRQILQNMGTRPNKKVYERKIRLCQEIL--------LVLKVVTPGI 407
                      ||:|.:.  :.|.|...| :|.:.:  :::..|:|..        .||..:..|:
Mouse   651 ----------DLQQQVC--MAQKLLRTG-KPEQAI--QQLLRCREAAESFLSAEHTVLGEIEDGL 700

  Fly   408 SRLKAIA---LYELANTQAELARKMYTEMEH--SANDLLAELERVEVMLRESLRMLLFEPLATPE 467
            ::..|..   |...|:.|..|   ...|..|  |:.::..||.:        |..:||..||.||
Mouse   701 AQAHATLGNWLKSAAHVQKSL---QVVETRHGPSSVEIGHELFK--------LAQVLFNGLAVPE 754

  Fly   468 G-----QLTRSMLRELKELQDDIKNLRE 490
            .     :..|.:|.......::::.|||
Mouse   755 ALSAIWKAERILLVHCGPESEEVRELRE 782

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.