Protein Alignment: SmydA-6 and Smyd4

• Sequence 1: NP_611182.1
• Gene: SmydA-6
• FlyBaseID: FBgn0034183
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001096081.1
• Gene: Smyd4
• MGIID: 2442796
• Length: 799
• Species: Mus musculus
• Alignment Length: 613
• Identity: 117/614 (19%)
• Similarity: 204/614 (33%)
• Gaps: 217/614 (35%)

  Fly    21 GRFAVALCNVRAGETLLLENPIVVLPLMGER-RCSKCF------NLT--ESFCRKCRLLAL---- 72
            ||..||..::..||.|:.|:..|.:.:.||. |...|.      .:|  :.:|.:|....|
Mouse   244 GRHLVATKDILPGELLVKEDAFVSVLIPGEMPRPHHCLENKWDTRVTSGDLYCHRCLKHTLATVP 308

  Fly    73 CEDCS--DHDERDCKRLA-EMNFSDD------------------QVELLQKKEHTEIQPVLKCL- 115
            |..||  .:..::|.:.| ::..|.:                  ::.||.:.|  ::..|::.|
Mouse   309 CGSCSYAKYCSQECMQQAWDLYHSTECSLGGLLLTLGVFCHVALRMTLLARFE--DVDRVVRMLC 371

  Fly   116 --------LLREHEETLPLYEEMSQMDSQLMTRRG--------------------------TEVW 146
                    .|.|.:..:..::..||.:|:..::.|                          ||
Mouse   372 DEVGSTDTCLPESKNLVKAFDYTSQGESEEKSKIGEPPIPGCNVNGKYGSNYNAIFSLLPHTE-- 434

  Fly   147 KNYQEHAF-TPLDYGGVLAQLRGAADEDLVQGLLGILDINAYEIRAPEV--------------GG 196
            |:..||.| ..:....:..||:  ||           .:.|..:::|::              |.
Mouse   435 KHSPEHRFICAISVSALCRQLK--AD-----------SVQAQTLKSPKLKAVTPGLCADLTVWGA 486

  Fly   197 AM------------------------------------RGLYRRAGLFAHSCTPNLVISIDDEQR 225
            ||                                    .|::....|..|||.||..:|.....
Mouse   487 AMLRHMLQLQCNAQAITSICHTGSNESIITNSRQIRLATGIFPVVSLLNHSCRPNTSVSFTGTV- 550

  Fly   226 IKVYANRFIAAGEILYNCY--TNVLLGTEERRKILKVGKCFDCSCPRCQDPT---ELGTHMSSFI 285
            ..|.|.:.||.|:.:.:||  ....:|..||::.|.....|||.|..|...|   .......:|.
Mouse   551 ATVRAAQRIAKGQEILHCYGPHESRMGVAERQQRLSSQYFFDCRCGACHAETLRAAAAPRWEAFC 615

  Fly   286 CSQCSCVDGYIVRQPDTGIWQCLLNPEHTLKQEFVSNMLERAKEEIFHARDDIYRQELLLAKLSR 350
            |..|..:      .....:..|        ..|..:|.:.|               :.|:::|.
Mouse   616 CKTCRAL------MQGNDVLSC--------SNESCTNSVSR---------------DQLVSRLQ- 650

  Fly   351 LLHRNHFLMLDLKQNIASILRQILQNMGTRPNKKVYERKIRLCQEIL--------LVLKVVTPGI 407
                      ||:|.:.  :.|.|...| :|.:.:  :::..|:|..        .||..:..|:
Mouse   651 ----------DLQQQVC--MAQKLLRTG-KPEQAI--QQLLRCREAAESFLSAEHTVLGEIEDGL 700

  Fly   408 SRLKAIA---LYELANTQAELARKMYTEMEH--SANDLLAELERVEVMLRESLRMLLFEPLATPE 467
            ::..|..   |...|:.|..|   ...|..|  |:.::..||.:        |..:||..||.||
Mouse   701 AQAHATLGNWLKSAAHVQKSL---QVVETRHGPSSVEIGHELFK--------LAQVLFNGLAVPE 754

  Fly   468 G-----QLTRSMLRELKELQDDIKNLRE 490
            .     :..|.:|.......::::.|||
Mouse   755 ALSAIWKAERILLVHCGPESEEVRELRE 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-6	NP_611182.1	SET	<179..244	CDD:279228	19/115 (17%)
Smyd4	NP_001096081.1	TPR_11	68..132	CDD:290150
		TPR repeat	68..96	CDD:276809
		TPR repeat	101..136	CDD:276809
		S-adenosyl-L-methionine binding. {ECO:0000250}	112..114
		zf-MYND	296..335	CDD:280009	9/39 (23%)
		SET	<524..570	CDD:279228	15/47 (32%)
		S-adenosyl-L-methionine binding. {ECO:0000250}	535..536		0/1 (0%)
		TPR_12	658..725	CDD:290160	14/73 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900