Protein Alignment SmydA-6 and Smyd2

DIOPT Version :10

• Sequence 1: NP_611182.1
• Gene: SmydA-6 / 36917
• FlyBaseID: FBgn0034183
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_081072.1
• Gene: Smyd2 / 226830
• MGIID: 1915889
• Length: 433
• Species: Mus musculus
• Alignment Length: 463
• Identity: 97/463 - (20%)
• Similarity: 178/463 - (38%)
• Gaps: 101/463 - (21%)

  Fly    21 GRFAVALCNVRAGETLLLENPIVVLPL-MGER--RCSKCFNLTE--SFCRKCRLLALCE-DCSDH 79
            ||...||.....|: ||...|.....| :|||  .|..||...|  |.|.:|:....|: :|...
Mouse    18 GRGLRALRPFHVGD-LLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDVECQKE 81

  Fly    80 D----ERDCKRLAEM--NFSDDQVE------LLQKKEHTEIQPVLKCLLLREHEETLPLYEEMSQ 132
            |    :.:|..:..:  |::..:..      |.::|.|.|..|..|.|.:||.|..|   :::..
Mouse    82 DWPLHKLECSSMVVLGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVREFESHL---DKLDN 143

  Fly   133 MDSQLMTRRGTEVWKNYQEHAFTPLDYGGVLAQLRGAADEDLVQGLLGILDINAYEIRAPEVGGA 197
            ....|:......:.:.|.::...| |:..::.             |...::.|.:.|...|:...
Mouse   144 EKKDLIQSDIAALHQFYSKYLEFP-DHSSLVV-------------LFAQVNCNGFTIEDEELSHL 194

  Fly   198 MRGLYRRAGLFAHSCTPNLVISIDDEQRIKVYANRFIAAGEILYNCYTNVLLGTEERRKILKVGK 262
            ...::....|..|||.||::::... ...:|.|.:.|..|:.::..|.::|..||:|...|:...
Mouse   195 GSAIFPDVALMNHSCCPNVIVTYKG-TLAEVRAVQEIHPGDEVFTSYIDLLYPTEDRNDRLRDSY 258

  Fly   263 CFDCSCPRC----QDPTELGTHMSSFICSQCSCVDGYIVRQPDTGIWQCLLNPEHTLKQEFVSNM 323
            .|.|.|..|    :|..::.                  ||:        |.:|.   :.|.:.:|
Mouse   259 FFTCECRECTTKDKDKAKVE------------------VRK--------LSSPP---QAEAIRDM 294

  Fly   324 LERAK---EEIFHARDDIYRQ--------ELLLAKLSRLLHRNHFLMLDLKQNIASILRQILQNM 377
            :..|:   ||...|:.  |:.        ||...|:|.:...::..||.:          :.|.|
Mouse   295 VRYARNVIEEFRRAKH--YKSPSELLEICELSQEKMSSVFEDSNVYMLHM----------MYQAM 347

  Fly   378 GTRPNKKVYERKIRLCQEILLVLKVVTPGISRLKAIALYELANTQAELARKMYTEMEHSANDLLA 442
            |.....:.:|..::..|      |::.| .|:...:....:|:...:|.| :|..:|:.|....|
Mouse   348 GVCLYMQDWEGALKYGQ------KIIKP-YSKHYPVYSLNVASMWLKLGR-LYMGLENKAAGEKA 404

  Fly   443 ELERVEVM 450
            ..:.:.:|
Mouse   405 LKKAIAIM 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-6	NP_611182.1	SET_SMYD	<185..271	CDD:380997	22/85 (26%)
Smyd2	NP_081072.1	SET_SMYD2	7..269	CDD:380979	63/269 (23%)
		zf-MYND	52..90	CDD:460312	10/37 (27%)
		TPR_10	388..422	CDD:463861	7/26 (27%)