DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf6 and chia.3

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_998378.1	Gene:	chia.3 / 406819	ZFINID:	ZDB-GENE-040426-2891	Length:	471	Species:	Danio rerio

Alignment Length:	462	Identity:	112/462 - (24%)
Similarity:	198/462 - (42%)	Gaps:	106/462 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LAIVSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGI 70
            :|.:||.|..:..|         ..:.||:.:.|..:.|:||.....::|.|  |.:|:|.::.|
Zfish     7 IAGLSLVLCHVAFS---------MEMACYFTNWSQYRPGIGKYTPANVDPYL--CTHLIYAFSII 60

  Fly    71 -ERDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPN----K 130
             :|:.......|.:.       ||:....||.|.|.:|.||:|||             .|    :
Zfish    61 NQRNELVTYEWNDET-------LYKAFNELKNKNPTLKTLLAVGG-------------WNFGSAQ 105

  Fly   131 YLELLESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIV 195
            :..::.:|..|..|:.:....::|:||||||:.|::|..:        ||
Zfish   106 FSIMVSNPANRKTFIQSTIKFLRTHGFDGLDLDWEYPGAR--------GS--------------- 147

  Fly   196 DEKSEEHKEQFTALLRDVKNAFRPDN-------LLLSTTVLP---NVNSSLFYDIPAVVNYLDFV 250
               ..|.|::||.|.:::..|:..::       |:|:..|..   .::..  |:|..:..||:|:
Zfish   148 ---PPEDKQRFTLLCKELVAAYEAESKATGNPQLMLTAAVSAGKGTIDDG--YEIAEIAKYLNFI 207

  Fly   251 NLGTFDFF-TPQRNPEVADYAAPIYELSERNPE---FNVAAQVKYWLRNNCPASKINVGVATYGR 311
            |:.|:||. |.:|   ...:.:|:|:.|:...:   ||....::||..|..|..|:.:|.|.|||
Zfish   208 NVMTYDFHGTWER---FTGHNSPLYQGSKDEGDLIYFNTDYAMRYWRDNGTPVEKLRMGFAAYGR 269

  Fly   312 PWKLTDDSGDTGVPPVKDVKDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDP 376
            .::||......|.|    ....|..|..|:..|.:|:.|:|..|......::.....|
Zfish   270 TFRLTSSDTSVGAP----ASGPASAGTYTREAGFWSYYEICGFLEGTTIQWIDDQKVP------- 323

  Fly   377 AKRFGSYAYRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRG-LCTNEKY 440
                  ||.:       |..||.|:..::...|..|::.:|.||..::.|..|||.| .|:...:
Zfish   324 ------YATK-------NSEWVGFDTKESYETKVRYLKDKNFGGAFVWALDLDDFAGQFCSQGNH 375

  Fly   441 PILRAIK 447
            |::..::
Zfish   376 PLMAHLR 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	107/438 (24%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	101/416 (24%)
chia.3	NP_998378.1	Glyco_18	24..363	CDD:214753	101/415 (24%)
		GH18_chitolectin_chitotriosidase	25..385	CDD:119351	107/435 (25%)
		ChtBD2	421..469	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592077
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840