DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Idgf6 and Cht6

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	116/458 - (25%)
Similarity:	198/458 - (43%)	Gaps:	88/458 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LAIVSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGI 70
            |..::.|:.  :||..|       .:||||.:.|..:.|..|.....:.|.|  |.:|||.:.|.
  Fly    16 LCALAYCIN--EASSEG-------RVVCYYTNWSVYRPGTAKFNPQNINPYL--CTHLVYAFGGF 69

  Fly    71 ERDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELL 135
            .:|:........|   |:.:|.|...|.||.....:|.::::||         ..|..:::..|:
  Fly    70 TKDNQMKPFDKYQ---DIEQGGYAKFTGLKTYNKQLKTMIAIGG---------WNEASSRFSPLV 122

  Fly   136 ESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSE 200
            .|...|.:|:..:...::...|||:|:.|::|.::            :|.|             .
  Fly   123 ASNERRQQFIKNILKFLRQNHFDGIDLDWEYPAHR------------EGGK-------------S 162

  Fly   201 EHKEQFTALLRDVKNAFRPD-------NLLLSTTVLPNVN-SSLFYDIPAVVNYLDFVNLGTFDF 257
            ..::.:...:::::..|..:       .|||:..|...:. ....||:|.:..|||:.|:.|:||
  Fly   163 RDRDNYAQFVQELRAEFEREAEKTGRTRLLLTMAVPAGIEYIDKGYDVPKLNKYLDWFNVLTYDF 227

  Fly   258 FTPQRNPEVADYAAPIYELSE-----RNPEFNVAAQVKYWLRNNCPASKINVGVATYGRPWKL-T 316
            .: ...|.| ::.||:|.|.|     .:.|.|:...:||:|:......|:.:|:.||||.:.| .
  Fly   228 HS-SHEPSV-NHHAPLYSLEEDSEYNYDAELNIDYSIKYYLKAGADRDKLVLGIPTYGRSYTLIN 290

  Fly   317 DDSGDTGVPPVKDVKDEAP--VGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKR 379
            ::|.:.|.|.      |.|  .|..|:..|..::.|:|..|.:         :.....||..|..
  Fly   291 EESTELGAPA------EGPGEQGDATREKGYLAYYEICQTLKD---------DPEWTVVQPNANV 340

  Fly   380 FGSYAYRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCTNEKYPILR 444
            .|.||||       ...||.::|......||.||..:.|||:..:.:..|||||.|..:.||::.
  Fly   341 MGPYAYR-------RNQWVGYDDEAIVRKKAEYVVAQGLGGIMFWAIDNDDFRGTCNGKPYPLIE 398

  Fly   445 AIK 447
            |.|
  Fly   399 AAK 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	111/434 (26%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	101/413 (24%)
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	101/414 (24%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	111/433 (26%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910