DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf6 and cht-1

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_508588.1	Gene:	cht-1 / 180628	WormBaseID:	WBGene00000503	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	440	Identity:	112/440 - (25%)
Similarity:	186/440 - (42%)	Gaps:	95/440 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIERDSHKAVSLNQQLDLD---LGKGLYR 94
            ||:.:.:..::|..|.|.::..|.|  |.::::.:..:..|  ..|......||.   .|:|:||
Worm    57 CYFTNWAQYRQGRAKFVPEDYTPGL--CTHILFAFGWMNAD--YTVRAYDPADLPNDWAGEGMYR 117

  Fly    95 TVTRLKRKYPNVKILLSVGG-DKDIELDKDAKELPNKYLELLESPTGRTRFVNTVYSLVKTYGFD 158
            .|.:||.....:|.|||.|| .....|          :..:..|...|..|:::..:.|:|:|||
Worm   118 RVNKLKVTDTQLKTLLSFGGWSFGTAL----------FQGMAASSASRKVFIDSAITFVRTWGFD 172

  Fly   159 GLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEHKEQFTALLRDVKNAFR----- 218
            |:|:.|::|        ||...:                      ..:.||::::|.|..
Worm   173 GIDIDWEYP--------SGATDM----------------------ANYVALVKELKAACESEAGS 207

  Fly   219 --PDNLLLSTTVLPN-VNSSLFYDIPAVVNYLDFVNLGTFDFFTPQRNPEVADYAAPIYELSERN 280
              .|.||::..|... ......||||.:....||:.|.::|||....:  :..:.:|:|..:|..
Worm   208 TGKDRLLVTAAVAAGPATIDAGYDIPNLAPNFDFILLMSYDFFGAWAS--LVGFNSPLYATTELP 270

  Fly   281 PE---FNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDS----GDTGVPPVKDVKDEAPVGG 338
            .|   :||.:..:||.:...|..||.||:.||||.|.|.:.|    |.:|.|        |.:..
Worm   271 AEWNGWNVDSSARYWNQKGMPKEKIIVGMPTYGRGWTLNNASAINPGTSGSP--------AKITQ 327

  Fly   339 NTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNGIWVSFEDP 403
            ..|..|:.::.|.|.:|.|....|....:.....||                 |:.  |.|::|.
Worm   328 YVQEAGVGAYFEFCEMLANGATRYWDSQSQVPYLVQ-----------------GNQ--WWSYDDE 373

  Fly   404 DTAADKAGYVRTENLGGVALFDLSYDDFRGLCTN---EKYPILRAIKYRL 450
            ::.|:|..||:.|..||..::.|.:|||...|:|   :.||::..|...|
Worm   374 ESFANKMAYVKREGYGGAFVWTLDFDDFNAGCSNSNGQLYPLISVIAKEL 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	111/438 (25%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	103/414 (25%)
cht-1	NP_508588.1	GH18_chitolectin_chitotriosidase	55..423	CDD:119351	111/438 (25%)
		Glyco_18	57..399	CDD:214753	103/414 (25%)
		CBM_14	481..532	CDD:279884
		CBM_14	567..615	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810