Protein Alignment: Idgf6 and CHI3L1

• Sequence 1: NP_001286499.1
• Gene: Idgf6
• FlyBaseID: FBgn0013763
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001267.2
• Gene: CHI3L1
• HGNCID: 1932
• Length: 383
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 121/438 (28%)
• Similarity: 190/438 (43%)
• Gaps: 103/438 (24%)

  Fly    31 LVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIERDSHKAVSLNQQLDLDLGKGLYRT 95
            |||||.|.|..:||.|....|.|:..|  |.:::|.:|.|..|.......|...       ||..
Human    24 LVCYYTSWSQYREGDGSCFPDALDRFL--CTHIIYSFANISNDHIDTWEWNDVT-------LYGM 79

  Fly    96 VTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLESPTGRTRFVNTVYSLVKTYGFDGL 160
            :..||.:.||:|.||||||         ......::.::..:...|..|:.:|...::|:|||||
Human    80 LNTLKNRNPNLKTLLSVGG---------WNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGL 135

  Fly   161 DVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEHKEQFTALLRDVKNAFRPD----- 220
            |:||.:|                               ....|:.||.|::::|..|..:
Human   136 DLAWLYP-------------------------------GRRDKQHFTTLIKEMKAEFIKEAQPGK 169

  Fly   221 -NLLLSTTVLP---NVNSSLFYDIPAVVNYLDFVNLGTFDFFTPQRNPEVADYAAPIYELSE-RN 280
             .||||..:..   .::||  |||..:..:|||:::.|:||....|.  ...:.:|::...| .:
Human   170 KQLLLSAALSAGKVTIDSS--YDIAKISQHLDFISIMTYDFHGAWRG--TTGHHSPLFRGQEDAS 230

  Fly   281 PE--FNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGVPPVKDVKDEAPVGGN---- 339
            |:  .|....|.|.||...||||:.:|:.|:||.:.|.  |.:|||        .||:.|.
Human   231 PDRFSNTDYAVGYMLRLGAPASKLVMGIPTFGRSFTLA--SSETGV--------GAPISGPGIPG 285

  Fly   340 --TQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNGIWVSFED 402
              |:..|..::.|:|        .:|:||....|..|..     .||     .||:.  ||.::|
Human   286 RFTKEAGTLAYYEIC--------DFLRGATVHRILGQQV-----PYA-----TKGNQ--WVGYDD 330

  Fly   403 PDTAADKAGYVRTENLGGVALFDLSYDDFRG-LCTNE-KYPILRAIK 447
            .::...|..|::...|.|..::.|..|||:| .|..: ::|:..|||
Human   331 QESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTNAIK 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	121/438 (28%)
		Glyco_18	31..429	CDD:214753	112/416 (27%)
CHI3L1	NP_001267.2	Glyco_18	23..357	CDD:214753	112/416 (27%)
		GH18_chitolectin_chitotriosidase	24..380	CDD:119351	121/438 (28%)
		Chitooligosaccharide binding	70..71		0/1 (0%)
		Chitooligosaccharide binding	97..100		2/12 (17%)
		Chitooligosaccharide binding	204..207		1/3 (33%)
		Important for AKT1 activation and IL8 production. {ECO:0000250}	324..338		4/16 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C66243508
eggNOG	1	0.900				E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR11177
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.930