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Protein Alignment Idgf6 and CHI3L1

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001267.2	Gene:	CHI3L1 / 1116	HGNCID:	1932	Length:	383	Species:	Homo sapiens

Alignment Length:	437	Identity:	121/437 - (27%)
Similarity:	190/437 - (43%)	Gaps:	103/437 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIERDSHKAVSLNQQLDLDLGKGLYRT 95
            |||||.|.|..:||.|....|.|:..|  |.:::|.:|.|..|.......|...       ||..
Human    24 LVCYYTSWSQYREGDGSCFPDALDRFL--CTHIIYSFANISNDHIDTWEWNDVT-------LYGM 79

  Fly    96 VTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLESPTGRTRFVNTVYSLVKTYGFDGL 160
            :..||.:.||:|.||||||         ......::.::..:...|..|:.:|...::|:|||||
Human    80 LNTLKNRNPNLKTLLSVGG---------WNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGL 135

  Fly   161 DVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEHKEQFTALLRDVKNAFRPD----- 220
            |:||.:|                               ....|:.||.|::::|..|..:
Human   136 DLAWLYP-------------------------------GRRDKQHFTTLIKEMKAEFIKEAQPGK 169

  Fly   221 -NLLLSTTVLP---NVNSSLFYDIPAVVNYLDFVNLGTFDFFTPQRNPEVADYAAPIYELSE-RN 280
             .||||..:..   .::||  |||..:..:|||:::.|:||....|.  ...:.:|::...| .:
Human   170 KQLLLSAALSAGKVTIDSS--YDIAKISQHLDFISIMTYDFHGAWRG--TTGHHSPLFRGQEDAS 230

  Fly   281 PE--FNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGVPPVKDVKDEAPVGGN---- 339
            |:  .|....|.|.||...||||:.:|:.|:||.:.|.  |.:|||        .||:.|.
Human   231 PDRFSNTDYAVGYMLRLGAPASKLVMGIPTFGRSFTLA--SSETGV--------GAPISGPGIPG 285

  Fly   340 --TQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNGIWVSFED 402
              |:..|..::.|:|        .:|:||....|..|..     .||     .||:.  ||.::|
Human   286 RFTKEAGTLAYYEIC--------DFLRGATVHRILGQQV-----PYA-----TKGNQ--WVGYDD 330

  Fly   403 PDTAADKAGYVRTENLGGVALFDLSYDDFRG-LCTNE-KYPILRAIK 447
            .::...|..|::...|.|..::.|..|||:| .|..: ::|:..|||
Human   331 QESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTNAIK 377

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.