Protein Alignment CG5065 and Far1

DIOPT Version :10

• Sequence 1: NP_611143.1
• Gene: CG5065 / 36860
• FlyBaseID: FBgn0034145
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_081655.2
• Gene: Far1 / 67420
• MGIID: 1914670
• Length: 515
• Species: Mus musculus
• Alignment Length: 492
• Identity: 198/492 - (40%)
• Similarity: 321/492 - (65%)
• Gaps: 0/492 - (0%)

  Fly   117 VPIAQFYAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARLTELLNAPLFE 181
            |.|.::|.|:::.:||.|||:||||:||||||||.:.::|:|:|.|.||....|:.|:|::.||:
Mouse     2 VSIPEYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSKLFD 66

  Fly   182 SLRQEKPKELSKVIPISGDITSEELGISEKDQNLLCRNVSVVFHSAATVKFDEKLKLSVTINMLG 246
            .||.|.|....|:|.|:.::|..:|.:||:|:.::..:.:|:||.||||:|:|.|:.:|.:|::.
Mouse    67 RLRDENPDFREKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIA 131

  Fly   247 TKRLVELCHRMLSLDALIHVSTAYCNCDRTDVSEVIYAPPYNPDDIISLINWLPEDILDQLTPRL 311
            |::|:.|..:|.:|:..:||||||..|:|..:.||:|.||.:|..:|..:.|:.:.:::.:||:|
Mouse   132 TRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKL 196

  Fly   312 IGKRPNTYTFTKALAEHMLLKEAGNLPVAIVRPSIVTASLNEPFAGWVDNFNGPTGLVSALAKGM 376
            ||.|||||.:||||||:::.:|...|.|||||||||.||..|||.||:||||||:||..|..||:
Mouse   197 IGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   377 FRTMMCEKNYVADMVPVDIVINLMIAAAWRTATRKSNNLLIYNCCTGQRNPIIWSEFVKHAMTSV 441
            .|||....|.:||:||||:|:|..:||||.:...:..|:::|||.||..||..|.|...|.:::.
Mouse   262 LRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNRPRNIMVYNCTTGSTNPFHWGEVEYHVISTF 326

  Fly   442 RKHPLEGCLWYPTGDLRMNRPMNTLNCIAKHFLPAYILDGVARIMGKKPFVVNVQNKIAKAVECL 506
            :::|||.....|..:|..|..:........|..||::.|...|:.|:.|.::....::.||:..|
Mouse   327 KRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPRMMKTITRLHKAMVFL 391

  Fly   507 EYFATRQWRFKDDNVHALLHTLSPKDREIFVFDVRHINWDKYVERYVLGFREFLFKQRPESLPAS 571
            |||.:..|.:..|||:.|::.|:|:|::.|..|||.::|.:|:|.|.:|.::::..:....|||:
Mouse   392 EYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVLNEEMSGLPAA 456

  Fly   572 RKRMLRLYYLHQLTKLVAVLLTWRFLMSRSKRLNDLW 608
            ||.:.:|..:......:.|:|.||..::||:...::|
Mouse   457 RKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIW 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5065	NP_611143.1	FAR-N_SDR_e	126..445	CDD:187547	145/318 (46%)
		Sterile	471..562	CDD:460779	30/90 (33%)
Far1	NP_081655.2	FAR-N_SDR_e	11..330	CDD:187547	145/318 (46%)
		Sterile	357..447	CDD:460779	30/89 (34%)
		Necessary and sufficient for PEX19-mediated localization into peroxisome membrane. /evidence=ECO:0000250|UniProtKB:Q8WVX9	451..507		13/43 (30%)