Protein Alignment Syn2 and sntg1

DIOPT Version :10

• Sequence 1: NP_788381.1
• Gene: Syn2 / 36848
• FlyBaseID: FBgn0034135
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: XP_004915254.1
• Gene: sntg1 / 100489155
• XenbaseID: XB-GENE-1011498
• Length: 522
• Species: Xenopus tropicalis
• Alignment Length: 500
• Identity: 198/500 - (39%)
• Similarity: 302/500 - (60%)
• Gaps: 20/500 - (4%)

  Fly    25 KVRTGMVHVSDGKSRPEPLRLNLTMELLSLQKLEVVTPSSCHPNGPPMESKERMVQITRQKQGGL 89
            :.:||:..:.||...|..:||:|..::|.:|:.:|:..|     |.|..|.||.|.|.||..||.
 Frog     9 EAKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVS-----GEPFYSGERTVAIRRQTVGGF 68

  Fly    90 GLSIKGGAEHKLPILISRIYKDQAADITGQLFVGDAIIKVNGEYITACPHDDAVNILRNAGDIVV 154
            |||||||:||.:|::||:|.|:|.|:::|.||:||||:::||..:..|.|::.|.:|||||:.|.
 Frog    69 GLSIKGGSEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCKHEEVVQVLRNAGEEVT 133

  Fly   155 LTVKHYRAATPFLQKQLTKD---TPDSDNDVTCAELKADEGYKSSVN-SGTISRSCSR-PMSICS 214
            |||...:.:..||:..|.:|   .|...:..|.:.| .|.|...:.: :.|.|.|||. |.|...
 Frog   134 LTVSFLKRSPAFLKLPLNEDCSCVPCDQSSGTSSPL-CDSGLHLNYHPNNTDSLSCSSWPTSPGL 197

  Fly   215 EPEKRWTDVVAVPLMMAYVTRYIYGTDKLRQNAFEVRGLNGISTGVIHCDELAILSQ----WLKL 275
            ..||||.|:..:||:.:.::::|.|||..|||||:|..::|:.:|:|.|    :|::    ||:.
 Frog   198 RWEKRWCDLRLIPLLHSRLSQHITGTDLCRQNAFQVTAVDGVGSGIIQC----LLAEECIDWLQS 258

  Fly   276 ITDNVVGLTHLQMKLYNRNFAVGERIEYMGWVNEGVINNNISWQSYKPRFLLLKGTEVMLFETPP 340
            |:.|:..||...:|..||||.|.::|.::|||.|.. .:.:....|.|:||.|:|:.:..|.:||
 Frog   259 ISANISNLTKHNIKKINRNFPVNQQIVFLGWVEERE-QDTLKDYVYSPKFLALRGSSLYKFNSPP 322

  Fly   341 LNVAGISKALVVYKVYQTMFRIVKESETVDSRQHCFLLQSSGHEPRYLSVETRQELLRIENSWNA 405
            :......:|...:.||:.|.:|.|:|:.:|.|:|||.:||...|..|.|||...:||:.|.::..
 Frog   323 VTTWDWMRAEKKFTVYEIMCKIFKDSDLLDRRKHCFGVQSETGEDLYFSVELECDLLQWEKAFQT 387

  Fly   406 AIVTSVIKLGRKTFAVSHHGKSGGLTLDWQAGFSLTEGAESATVWQYKFSQLRGSSDDGKSKLKL 470
            |....|.::..||:|........|||:|:..||...:.|..|.:|:||||||:|||||||||:|.
 Frog   388 ATFLEVERIQCKTYACVIESHLMGLTIDFGMGFICFDAATKAILWKYKFSQLKGSSDDGKSKIKF 452

  Fly   471 HFQDHDSRAIETKELECQVLQSLLFCMHAFLTAKVASVDPAFLSS 515
            .||:.|::.||.||||...|.::|.|:|:|..||||.:||.|:.|
 Frog   453 LFQNQDTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPRFVDS 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn2	NP_788381.1	PDZ_syntrophin-like	77..159	CDD:467262	44/81 (54%)
		PH	301..407	CDD:214574	36/105 (34%)
sntg1	XP_004915254.1	PDZ_syntrophin-like	56..138	CDD:467262	44/81 (54%)
		PH-like	288..381	CDD:473070	34/93 (37%)