Protein Alignment wcd and utp18

DIOPT Version :10

• Sequence 1: NP_611121.1
• Gene: wcd / 36831
• FlyBaseID: FBgn0262560
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_012827232.2
• Gene: utp18 / 549389
• XenbaseID: XB-GENE-981919
• Length: 522
• Species: Xenopus tropicalis
• Alignment Length: 510
• Identity: 148/510 - (29%)
• Similarity: 264/510 - (51%)
• Gaps: 39/510 - (7%)

  Fly    22 QQEQEKPAKIKRERYIPKASQAKELNYVEVPMEKVLFGDRQRLLTNL---AKS----VGQKLPND 79
            |::..|..:..|.:::...:...|.:.:   :|:::||.....:..|   :|:    .|..|.:|
 Frog    27 QEQNMKEEEELRTKHLKALADKPETDTI---LEELVFGGEDEFVEKLIGHSKARHTVSGDLLESD 88

  Fly    80 DEDEQEENPGQAKPGDKRKAAWSDSDD---EDLQV-----GDVKKATKHTGPLNHLRKDKSYKEY 136
            .|:|..||....    .||.||.|.:|   |::::     .|:.|:...|.    |.|:| .:..
 Frog    89 SEEETSENAAPL----ARKPAWVDEEDEHEENIEMTHRYRKDIMKSKTETA----LSKEK-LQAR 144

  Fly   137 LTARFQRTL-NQPKWA----EKKVKNEDDE-DVSSDEELLRTVGFIDRKARNSDLPQKTLNFKRV 195
            |..:||:.: ..|.||    :|::..||:| :..:|:.||...|  :..:::|.|.:..:..::.
 Frog   145 LQEQFQKAMGGVPSWACQGSKKRISKEDEESEEENDDNLLSKTG--NLLSQSSYLSKGVIQIRKC 207

  Fly   196 KDLNRATYAEGNATSIQFHPTSTAALVAGMNGLATIYAVDGQKNERLHNMRFKKFPLACSRIAPC 260
            .:.|....:....|::||||.:...:.||.:...:::.|||::|:::.::..:|||:..::.:..
 Frog   208 INANHERLSRVPLTTVQFHPLAQVVMTAGFDRSVSLFQVDGKRNQKIQSIHLEKFPIYKAQFSAD 272

  Fly   261 GTRAF-FGSVKPFYYSYDLLEAKESKL-KLPGAME-FMHRFEVSPCGKFIVTAGKFGAIHLLTAK 322
            |.:.. .|.....:|.||::......: ::.|..| .:.:|||||.|.|::..|..|.:|||:.|
 Frog   273 GEQVIATGLRSKMFYIYDMMGGNIITVPRIRGLEERVIQQFEVSPNGSFLLLNGSAGYLHLLSMK 337

  Fly   323 TNELLHSFKQEGKVKGFTWSSDSKRILVCGSTSNVSVLNLRQNLIEHIFMDDGCIHGESIQLSPN 387
            |.||:.|.|..||.....:|.||.::........|.|.::|.....:.|.|:|.|.|.||.||.:
 Frog   338 TKELIGSMKMNGKSMKAVFSPDSSKVFSNSDDGFVYVWDVRSRQCLNKFTDEGSICGTSIALSRD 402

  Fly   388 QRLLATGSQEGVVNIYDYESIFASKAPQPEKRFMNLRTAITDLQFNHSSELLAMCSSEAPNAFKL 452
            .|.::.||..||||||::|.......|:|.|..|||.|:.:.:.||..:|::|:.|::..:|.||
 Frog   403 GRYISCGSNSGVVNIYNHEDCLQQTNPRPLKAIMNLVTSASSIIFNPQTEIMAVASNKTDDAVKL 467

  Fly   453 AHFPSATVYSNFPAQNEK-VGFVTSMAFSPHSSFLAFATKGKQVPLFRLKYFKGY 506
            .|.||.:|:||||.||:| :....:|.|||.|.:.:.|....:..|:|||::..:
 Frog   468 VHIPSFSVFSNFPGQNKKSIHLPRAMDFSPRSGYFSIANNKGEALLYRLKHYSDF 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wcd	NP_611121.1	WD40	180..501	CDD:441893	103/324 (32%)
		WD40 repeat	209..247	CDD:293791	11/37 (30%)
		WD40 repeat	298..332	CDD:293791	17/33 (52%)
		WD40 repeat	337..371	CDD:293791	6/33 (18%)
		WD40 repeat	376..415	CDD:293791	16/38 (42%)
		WD40 repeat	428..465	CDD:293791	14/36 (39%)
utp18	XP_012827232.2	WD40	<219..497	CDD:441893	94/277 (34%)
		WD40 repeat	220..260	CDD:293791	11/39 (28%)
		WD40 repeat	265..304	CDD:293791	5/38 (13%)
		WD40 repeat	309..345	CDD:293791	16/35 (46%)
		WD40 repeat	352..387	CDD:293791	6/34 (18%)
		WD40 repeat	394..436	CDD:293791	18/41 (44%)
		WD40 repeat	442..480	CDD:293791	14/37 (38%)