Protein Alignment CG7755 and IDH3A

DIOPT Version :10

• Sequence 1: NP_611110.2
• Gene: CG7755 / 36816
• FlyBaseID: FBgn0034105
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_005521.1
• Gene: IDH3A / 3419
• HGNCID: 5384
• Length: 366
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 79/355 - (22%)
• Similarity: 155/355 - (43%)
• Gaps: 54/355 - (15%)

  Fly    51 GGINTVSLVTGTTIIGQQGAQFVSSLLSSSRVPVEVQVIEAGQDDEYFHSVLRNRTAVHVDN--- 112
            ||:.||:|:.|.. ||.:.:..|..:..:::.|::.:.              ||.||:....
Human    29 GGVQTVTLIPGDG-IGPEISAAVMKIFDAAKAPIQWEE--------------RNVTAIQGPGGKW 78

  Fly   113 QADAEAKQKA-----------------------LKICNDLDLYVFKTRTRSFPGFKCRFPGVDIQ 154
            ...:|||:..                       |.:....|||.......|..|:|..:..|:|.
Human    79 MIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIV 143

  Fly   155 LIGQNNMGIFNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEWPISD 219
            .|.:|..|.::.:|:..|:|||:::.::::..:.:...:||:.|....|..||.::||....:||
Human   144 TIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSD 208

  Fly   220 GSLVEAAQRLHCHYKDCLELELMEVEEAISRLMTEPTYFDCLFASERYATFLSAICSGVCGGANL 284
            |..::..:.:....|| ::...|.::.....::.:|:.||.|.....|...||.:|:|:.||..:
Human   209 GLFLQKCREVAESCKD-IKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGV 272

  Fly   285 FSAVEIGDHH-AVFKPLQ---TKLSLTNYANLSAYGIVSTIVDLFQHLGHDKCADALWCELKRTM 345
            ..:..||.:. |:|:.:.   ..::..:.||.:|  ::.:.|.:.:|:|....|..:......|:
Human   273 TPSGNIGANGVAIFESVHGTAPDIAGKDMANPTA--LLLSAVMMLRHMGLFDHAARIEAACFATI 335

  Fly   346 DEG-IRTKEFGGQDTGEYVICNIINQLRCR 374
            .:| ..||:.||.     ..|:...:..||
Human   336 KDGKSLTKDLGGN-----AKCSDFTEEICR 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7755	NP_611110.2	Iso_dh	<128..371	CDD:444908	59/247 (24%)
IDH3A	NP_005521.1	mito_nad_idh	29..362	CDD:272942	79/355 (22%)