Protein Alignment CngA and LOC4576205

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_061498773.1
• Gene: LOC4576205 / 4576205
• VectorBaseID: AGAMI1_000492
• Length: 927
• Species: Anopheles gambiae
• Alignment Length: 634
• Identity: 254/634 - (40%)
• Similarity: 362/634 - (57%)
• Gaps: 86/634 - (13%)

  Fly   165 PEEAIARADHDTQQK--QHYQPNASDSSYVE--------NGRKLIQEPSKRS--------KPSAL 211
            |.||:. :|.:|.|.  .|.:.:.|..|.::        :|.:|.|..|::.        ..|..
Mosquito   108 PLEAVG-SDFNTIQSSADHNRNSVSRQSLMDIVSSKLGMSGPQLGQSISQQGFFSSRDSLSASGT 171

  Fly   212 RRTLQA----------LRQRLTKRNRPK-----PPDWFLEKFSNT----TNTDKIGKGCPAMEDA 257
            .|.|.:          |.::..||.|.|     ||  .|..:|.|    :|.:.:|   |.....
Mosquito   172 SRPLHSHVSATTSEMDLSRKDRKRERSKLKAADPP--LLGSWSRTGPRESNANAMG---PCATTR 231

  Fly   258 ALSSEIR----GSSVLCN-----------------------RLS--VDPTLQSHYRWLAIVSLAV 293
            |.::.:.    |:...||                       |.|  .||..:..|.|..:||:|.
Mosquito   232 ASTNHLAAAPCGTGSTCNGADRYIFGRRSGCSTTSRKSNGRRWSFVFDPAGRLCYYWSMVVSMAF 296

  Fly   294 LYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLLDTLVHMHEGFLDQGLLVRDAFRLRRHYF 358
            |||...::.|..|.|||..:...|:.|||..||:||:|.|.|...|:|:.|:|..|:.:||:||.
Mosquito   297 LYNFWVIIYRFAFQEINGESIVLWFCLDYFSDFLYLVDILFHFRTGYLEDGVLQTDSTKLRQHYM 361

  Fly   359 HTKGWYLDVLSMLPTDLAYIWWPPETCSSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPNA 423
            ::..:|:|.|.:||.|..|          |.:....|:|..||::|.|.|.:.||||..|.|||.
Mosquito   362 NSTTFYIDCLCLLPLDFLY----------LSIGFNSILRSFRLVKIYRFWAFMDRTERHTNYPNL 416

  Fly   424 FRICKVVLAILVLIHWNACMYFAISYEIGFSSDSWVYNLNGTRNNTLQRQYIYSFYWSTLTLTTI 488
            ||...::..:||:.|||.|:|..|....||.|.:|||  :.:.:..:.:||:.|:||.||.||||
Mosquito   417 FRSTSLIHYLLVIFHWNGCLYHIIYKNNGFGSKNWVY--HDSESADVVKQYLQSYYWCTLALTTI 479

  Fly   489 GETPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGH 553
            |:.|.|.:..||:||:|..|.|:::|||::|::.:::::::.||.|||.::||||.||..|||.:
Mosquito   480 GDLPRPRSKAEYVFVIAQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPN 544

  Fly   554 ELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVL 618
            .|:.:||:||.|.|......||||.::.|||||||||||.||:||||:|.||.:||.|.|..|||
Mosquito   545 HLQVKVIKWFDYLWLTQKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVL 609

  Fly   619 KLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDDGITVLATLGAGSVFGEVSVLEI--AGNR 681
            ||:..:|||||:|||||:||||||||.||:|.||.|:|.||:|:|.|||.|||:|:|.:  ||..
Mosquito   610 KLRPVLFSPGDFICRKGEVGKEMYIVNRGRLQVVADNGKTVMASLKAGSYFGEISILNMGTAGKA 674

  Fly   682 TGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEARSTLTQRGCQLLRK 730
            .||||||:|||:||||||.|:|:|:|:.|.:||.||..|.....:.|.|
Mosquito   675 LGNRRTASVRSVGYSDLFVLSKKDMWDVLKEYPAARVRLEAIAVKRLEK 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	97/246 (39%)
		CAP_ED	604..717	CDD:237999	72/114 (63%)
		CLZ	720..790	CDD:465160	3/11 (27%)
LOC4576205	XP_061498773.1	None