Protein Alignment CngA and CG42260

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_001356969.1
• Gene: CG42260 / 37614
• FlyBaseID: FBgn0259145
• Length: 1269
• Species: Drosophila melanogaster
• Alignment Length: 905
• Identity: 287/905 - (31%)
• Similarity: 417/905 - (46%)
• Gaps: 204/905 - (22%)

  Fly    29 PKYGYNLSNRPMYRTTRLVGPASSAPAQLQLPC-----GSHQATLGVAPPPLEEISGGLFAPFAP 88
            ||:|.::|.:..:          ::...|..||     .||.||:..|
  Fly   359 PKFGQSVSQQGFF----------TSHDSLATPCASRASNSHMATVSTA----------------- 396

  Fly    89 TATITVEQAATSIPMAVDGEVHHLHYPRR-------------------SWQRKYRQGI--HRQPG 132
                              .|:..||..:|                   :|.|...:|.  :...|
  Fly   397 ------------------SEMDLLHNKQRNKSRGRLKTAASGDQPLLGTWNRSTGRGSQDNTLAG 443

  Fly   133 GGAEQDEDEEEDDDDVDEDDDDEFGASVCEDNPEEAIARAD----HDTQQKQHYQPNASDSSYVE 193
            |||          ..:.....:::|.:.|........:|:.    |:..|:.|:......|:...
  Fly   444 GGA----------TSLAMGGHNQYGGNYCNGTDRYPRSRSQQQGHHNAAQQAHHPYQLQHSASTV 498

  Fly   194 NGRKLIQEPSKRSKPSALRRTLQALRQRLTKRNRPKPPDWFLEKFSNTTNTDKIGKGCPAMEDA- 257
            :.......|..:..|..                 |.||........:.......|...|.....
  Fly   499 SHHPHAHGPPSQGGPGG-----------------PGPPHGGHPHHPHHGGAGSGGGSGPGSHGGQ 546

  Fly   258 --------ALSSEIRGSSVLCNRLS--VDPTLQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKS 312
                    ..|..||.::. ..:|.  .||..:..|.|..:||:|.|||...::.|..|.|||:.
  Fly   547 PHHQKPRRTASQRIRAATA-ARKLHFVFDPAGRLCYYWSMVVSMAFLYNFWVIIYRFAFQEINRR 610

  Fly   313 APAFWYTLDYLCDFIYLLDTLVHMHEGFLDQGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAY 377
            ..|.|:.||||.||:||:|.|.|...|:|:.|:|..||.:||.||.::..:|:|.|.:||.|..|
  Fly   611 TIAIWFCLDYLSDFLYLIDILFHFRTGYLEDGVLQTDALKLRTHYMNSTIFYIDCLCLLPLDFLY 675

  Fly   378 IWWPPETCSSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNAC 442
                      |.:....|:|..||::|.|.|.:.||||..|.|||.||...::..:||:.|||.|
  Fly   676 ----------LSIGFNSILRSFRLVKIYRFWAFMDRTERHTNYPNLFRSTALIHYLLVIFHWNGC 730

  Fly   443 MYFAISYEIGFSSDSWVYNLNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDVEYLFVVADF 507
            :|..|....||.|.:|||  :.:.:..:.:||:.|:||.||.|||||:.|.|.:..||:||:...
  Fly   731 LYHIIHKNNGFGSRNWVY--HDSESADVVKQYLQSYYWCTLALTTIGDLPKPRSKGEYVFVILQL 793

  Fly   508 LAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGA 572
            |.|:::|||::|::.:::::::.||.|||.::||||.||..|||.:.|:.:||:||.|.|.....
  Fly   794 LFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLWLTQKC 858

  Fly   573 LDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDV 637
            .||||.::.|||||||||||.||:||||:|.||.:||.|.|..|||:|:..:|||||||||||:|
  Fly   859 SDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICRKGEV 923

  Fly   638 GKEMYIVKRGKLSVVGDDGITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLA 702
            |||||||.||:|.||.|:|.||:|:|.|||.|||:|:|.:  ...||||||:|||:||||||.|:
  Fly   924 GKEMYIVNRGRLQVVADNGKTVMASLKAGSYFGEISILNM--GTAGNRRTASVRSVGYSDLFVLS 986

  Fly   703 KRDLWETLSDYPEAR-------------------------STLTQRGCQ---------------- 726
            |:|:|:.|.:||.||                         :.:....||
  Fly   987 KKDMWDVLKEYPAARVRLESIAVKRLEKYKKAPLEKVKYFNVVAMGRCQSTPGLVESCGRTSLEE 1051

  Fly   727 ------------LLRKDGLLDEQIFADSQRVH--DSIEGGIEKLELSVENLNMRLARLLAEYTAS 777
                        |:.....|.:|..|..|:.|  :|.:...:....|..:...||||.    |.|
  Fly  1052 MWLPPATAGASSLMHHHQALQQQHQASQQQPHRQESTQTSSQTHGYSPRSYADRLARA----TDS 1112

  Fly   778 QAKIKQRLAKLEMNGGPGTWRLECEPQSRARSGRLYSLQPKRRPRSRPDATAKSSDAAKQ 837
            ...:           .|.....|..|:||..|.  :|:    ||:|:|..|....|::.|
  Fly  1113 PRSV-----------SPSAHGSEERPRSRTTSH--HSI----RPQSQPSHTGHICDSSSQ 1155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	99/246 (40%)
		CAP_ED	604..717	CDD:237999	70/112 (63%)
		CLZ	720..790	CDD:465160	16/99 (16%)
CG42260	NP_001356969.1	Ion_trans	581..820	CDD:459842	101/250 (40%)
		CAP_ED	890..1004	CDD:237999	72/115 (63%)