Protein Alignment CngA and Cngl

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_727848.3
• Gene: Cngl / 32468
• FlyBaseID: FBgn0263257
• Length: 1970
• Species: Drosophila melanogaster
• Alignment Length: 767
• Identity: 239/767 - (31%)
• Similarity: 381/767 - (49%)
• Gaps: 154/767 - (20%)

  Fly   152 DDDEFGASVCEDNPEEAIARADHDTQQKQHYQPNAS--DSSYVENGRKLIQEPSKRSKPSALRRT 214
            |||...|:...|:..        .:|:|......||  ||.:..:.::.::          ||.|
  Fly   124 DDDNNSAAHSSDSKS--------PSQRKSRIGDGASDPDSDWTRSNQRWMK----------LRTT 170

  Fly   215 LQALRQRLTKRNRPKPP----DWFLEKFSNTTNTDKIGKGCPAMEDA---ALSSEI-----RGSS 267
            :|     ::...:.|||    |.||::||    |.:|.:....:||.   :.|.::     |...
  Fly   171 VQ-----ISSAIQKKPPLKREDSFLKRFS----TRQIPETQETVEDTGSESASGDVDKSVKRRRR 226

  Fly   268 VLCNRLS-VDPTLQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLLD 331
            .|..|.| |:|....::.||.::::.||||:..::.|..|.|:.:|.|.||...|.:.|.:::||
  Fly   227 YLQKRRSVVNPDENFYFYWLMMLTVCVLYNLWTLIVRQSFPELQQSVPTFWLICDSMTDVVFILD 291

  Fly   332 TLVHMHEGFLDQGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYIWWPPETCSSLYLPCPVIV 396
            .:|.:..|:|:|||:|.|..:|..||.|::.:..|:::::|.||.          .|.:....::
  Fly   292 IIVQLRTGYLEQGLMVYDDRKLACHYVHSRDFIFDMIALIPLDLL----------QLKMGTHPLL 346

  Fly   397 RLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISYEIGFSSDSWVYN 461
            |..|..::.|...::...|:.|.:||.:|:..::..:|:|.||..|.||.:|...||..| |||.
  Fly   347 RFTRFFKVYRSVRFYYIVESRTVWPNLWRVVNLIHILLILAHWFGCFYFLLSEAEGFQGD-WVYP 410

  Fly   462 LNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDVE--------------------------- 499
            .......||.|:|:.|.|||||||||||:.||||.:.|
  Fly   411 YRPGDYATLTRKYLGSLYWSTLTLTTIGDLPTPETNAEPNFSVDGPRSIPRRGIKSRLLQFGSSY 475

  Fly   500 -YLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWF 563
             |:|.:..:|.||.|||||||.:|::|:|.|..|:||:..:||.|.||...:|...::.||:||:
  Fly   476 GYIFTIVSYLIGVFIFATIVGQVGNVITNRNANRLEFERLLDGAKTYMRHHKVPGGMKRRVLRWY 540

  Fly   564 AYTWSQ---SGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVF 625
            .|:||:   .|..|....|..||||||.|:|:.|::..||:|.||.:.:|..|..||||:|..:|
  Fly   541 DYSWSRGRIQGGGDINTALGLLPDKLKTELALHVNLSVLKKVTIFQECQPEFLHDLVLKMKAYIF 605

  Fly   626 SPGDYICRKGDVGKEMYIVKRGKLSVVGDDGITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANV 690
            :|||.|||||:|.:||:|:..|.|.|:.:.| .||.|:.||..|||:.:|.:.|.   |:|||:|
  Fly   606 TPGDSICRKGEVAREMFIIADGILEVLSETG-KVLTTMKAGDFFGEIGILNLDGL---NKRTADV 666

  Fly   691 RSLGYSDLFCLAKRDLWETLSDYPEARSTLTQRGCQLLRKDGLLDEQIFADSQ------------ 743
            ||:|||:||.|::.|:...:.|||:|:..|...|.:.|.:...:::: :|.:|
  Fly   667 RSVGYSELFSLSREDVLAAMKDYPDAQEILQTLGRKRLMEVRCVNKK-YAKAQSDKEAAAYAAAH 730

  Fly   744 ----------RVH--DSIEGG-----IEKLELSVENLNMRLARLLAEYTASQAKIKQRLAKLEMN 791
                      :||  ||.|..     ::||:..|:.....|.:......:.::
  Fly   731 PHHHQSHHQGQVHQSDSSENSASKKIVDKLKHDVKGFRNVLKKSRTSRKSDES------------ 783

  Fly   792 GGPGTWRLECEPQSRARSGRLYSLQP-------KRRPRSRPDATAKSSDAAK 836
                   ||.:|        |::..|       ||..|.|.|  .|.:|:|:
  Fly   784 -------LEMQP--------LHNTSPRGSKILLKRMSRVRSD--EKDADSAE 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	92/274 (34%)
		CAP_ED	604..717	CDD:237999	53/112 (47%)
		CLZ	720..790	CDD:465160	14/98 (14%)
Cngl	NP_727848.3	Ion_trans	240..509	CDD:459842	93/279 (33%)
		CAP_ED	584..696	CDD:237999	54/115 (47%)
		dermokine	<1688..>1775	CDD:455732