Protein Alignment CngA and eag

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_001036275.1
• Gene: eag / 32428
• FlyBaseID: FBgn0000535
• Length: 1270
• Species: Drosophila melanogaster
• Alignment Length: 798
• Identity: 181/798 - (22%)
• Similarity: 319/798 - (39%)
• Gaps: 170/798 - (21%)

  Fly   160 VC-----EDNPEEAIARADH--DTQQKQHYQPNASDSSYVENGRKLIQEPSKRSKPSALRRTLQA 217
            ||     |...:|.:.|.::  :.||:..::......:.::.|..|.|....:::.:.|...||.
  Fly    69 VCGFMYGELTDKETVGRLEYTLENQQQDQFEILLYKKNNLQCGCALSQFGKAQTQETPLWLLLQV 133

  Fly   218 LRQR----------LTKRN---RPKPPD-------WFLEKFS----NTTNTDKIGKGCPAMEDAA 258
            ...|          ||.|:   ..:|.|       ..|.||:    :.|.:.:.....|.::|..
  Fly   134 APIRNERDLVVLFLLTFRDITALKQPIDSEDTKGVLGLSKFAKLARSVTRSRQFSAHLPTLKDPT 198

  Fly   259 LSSEIRGSSVLCNRLSVDPTLQSHYR----------------------WLAI-----VSLAVLYN 296
            ..|.      |.:.:|:...:...||                      |:.:     .::.|.||
  Fly   199 KQSN------LAHMMSLSADIMPQYRQEAPKTPPHILLHYCAFKAIWDWVILCLTFYTAIMVPYN 257

  Fly   297 IIFVVGRAVFWEINK-SAPAFWYTLDYLCDFIYLLDTLVHMHEGFLDQ-GLLVRDAFRLRRHYFH 359
            :.|.         || |.......:|.:.|.|:.:|.:::.|..|:.. |.:|.|...:|.:|.
  Fly   258 VAFK---------NKTSEDVSLLVVDSIVDVIFFIDIVLNFHTTFVGPGGEVVSDPKVIRMNYL- 312

  Fly   360 TKGWY-LDVLSMLPTDLAYIWWPPET-CSSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPN 422
             |.|: :|:||.||.|:...:...|. ..||:....|:    ||||:.|:....||   ...|..
  Fly   313 -KSWFIIDLLSCLPYDVFNAFDRDEDGIGSLFSALKVV----RLLRLGRVVRKLDR---YLEYGA 369

  Fly   423 AFRICKVVLAILVLIHWNACMYFAIS-----------------------YEIGFSSDSWVYNLNG 464
            |..|..:...:|| .||.||::::|.                       |...:|:|:....:||
  Fly   370 AMLILLLCFYMLV-AHWLACIWYSIGRSDADNGIQYSWLWKLANVTQSPYSYIWSNDTGPELVNG 433

  Fly   465 TRNNTLQRQYIYSFYWSTLTLTTIG-ETPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMISNM 528
            ....::   |:.:.|::...:|::| .....|.|.|.:|.:...:...|::|||.|::.::|..|
  Fly   434 PSRKSM---YVTALYFTMTCMTSVGFGNVAAETDNEKVFTICMMIIAALLYATIFGHVTTIIQQM 495

  Fly   529 NVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAIQ 593
            ..|..::.:.::.|:::|....|...|..||:.:...||:.:..||.|:||...|..:||:|.:.
  Fly   496 TSATAKYHDMLNNVREFMKLHEVPKALSERVMDYVVSTWAMTKGLDTEKVLNYCPKDMKADICVH 560

  Fly   594 VHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDDGIT 658
            ::.....:...|.....|.|.||.:...:...:|||.:...|:....:..:..|.|.|:.||  .
  Fly   561 LNRKVFNEHPAFRLASDGCLRALAMHFMMSHSAPGDLLYHTGESIDSLCFIVTGSLEVIQDD--E 623

  Fly   659 VLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEARSTLTQR 723
            |:|.||.|.|||:    :...:....:..||||:|.|.||..:.:..|.|.|..|....::..:
  Fly   624 VVAILGKGDVFGD----QFWKDSAVGQSAANVRALTYCDLHAIKRDKLLEVLDFYSAFANSFAR- 683

  Fly   724 GCQLLRKDGLLDEQIF---ADSQRVHDSIEGGIEKLELSVENLNMRLARLLAEYTAS---QAKIK 782
              .|:....|....||   ||.:|..:..|....:.:|. :|.:..:.::.:::..:   ||..|
  Fly   684 --NLVLTYNLRHRLIFRKVADVKREKELAERRKNEPQLP-QNQDHLVRKIFSKFRRTPQVQAGSK 745

  Fly   783 QRLAKLEMNGGPGTWRLECEPQSRARSG-------------------RLYSL------QPKRRPR 822
                  |:.||.|        ||....|                   |:.|.      .|...|.
  Fly   746 ------ELVGGSG--------QSDVEKGDGEVERTKLPAKLTLTEDARILSTAAAPSPSPSPSPS 796

  Fly   823 SRPDATAKSSDAAKQNTL 840
            |.| .:|:|:.|:|...|
  Fly   797 SGP-PSARSTRASKWGRL 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	69/301 (23%)
		CAP_ED	604..717	CDD:237999	34/112 (30%)
		CLZ	720..790	CDD:465160	13/75 (17%)
eag	NP_001036275.1	PAS_9	40..155	CDD:463873	17/85 (20%)
		Ion_trans	238..499	CDD:459842	68/282 (24%)
		CAP_ED	571..682	CDD:237999	34/116 (29%)