Protein Alignment CngA and che-6

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_001343628.1
• Gene: che-6 / 182823
• WormBaseID: WBGene00000487
• Length: 655
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 176/584 - (30%)
• Similarity: 294/584 - (50%)
• Gaps: 97/584 - (16%)

  Fly   282 HYRWLAIVSLAVLYN----IIFV---VGRAVFWEINKSAPAFWYTLDYLCDFIYLLDTLVHMHEG 339
            :|.|...||..|:||    :||:   :....||.        |..|:.:.|.::::|..|.....
 Worm    68 YYIWSFFVSFGVMYNMFAMVIFIFADIKTQYFWN--------WIFLNVMFDMVFIVDIFVQSRLT 124

  Fly   340 FLDQGLLVRDAFRLRRHYFHTKGWYL----DVLSMLPTDLAYIWWPPETCSSLYLPCPVIVRLNR 400
            :|.:|..|::..:||::||..|   |    |:..:||.|  ::.:..::.|        :||..|
 Worm   125 YLHEGEEVKNTKKLRKNYFFQK---LKVANDIFCLLPLD--FLLFFDDSMS--------LVRTIR 176

  Fly   401 LLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISY----------EIGFS- 454
            ::::.||.::..||:..|.:|.||:|..:.::.:||.|||||:||..|.          |.|||
 Worm   177 IVKVIRLMDFVQRTQQQTTFPRAFKIILLAVSCIVLFHWNACLYFLFSLYEGITEESQTEFGFSY 241

  Fly   455 ----------------SDSW-------VYNLNGTRNN-------------------TLQRQYIYS 477
                            .:.|       ..:|:..|::                   ...|:|..|
 Worm   242 YKVFEPVFPTCQAYYDENCWFGEDIDHTLDLDDVRDSYKKEMAEYWKDKHYRWTTGNFSREYSMS 306

  Fly   478 FYWSTLTLTTIGETPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGV 542
            .|||.||:||.|:.|.|....:....|.|.|.|||:||||:|::||:::.|:....||:..|||:
 Worm   307 IYWSALTITTCGQQPWPSTSSQNSLEVFDTLIGVLVFATIIGSVGSVVTQMSQTVNEFRQMMDGI 371

  Fly   543 KQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHD 607
            |.||.:|.|...::.|.:..|.|..:.:...|||.:|:.||.:|:|.||..:||:||:.::||..
 Worm   372 KFYMKYREVNSAIQERALSCFMYLMAHNQLDDEEGILSLLPPRLQANIAANLHMETLQNIQIFAL 436

  Fly   608 TEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDDGITVLATLGAGSVFGEV 672
            .|...:..:||.:|.|||||.||:|||.:..||::|||:|||.|:.||....:..|..|:.|||:
 Worm   437 CESRFMHEVVLLVKQQVFSPNDYLCRKNEKAKELFIVKKGKLRVIDDDTGEEMGELTEGATFGEL 501

  Fly   673 SVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEARSTLTQRGCQLLRKDGLLDEQ 737
            |::.:.||..|.||..:::|:|:||::.|.:.|:...|.::|:...|:......||...|||:..
 Worm   502 SIVYVKGNLLGTRRCCSLQSVGFSDIYVLYRDDVSRLLQEFPQEYKTIVMNARNLLHSRGLLETT 566

  Fly   738 IF------ADSQRVHD------SIEGGIEKLELSVENLNMRLARLLAEYTASQAKIKQRLAKLE 789
            ..      :|.:...|      |:...:.:|...::.||..:..::..::.|.:..||::..||
 Worm   567 ELGEMCDPSDHEEADDLVLEEMSVVEQLNRLNGIIDGLNGNMNVMILSFSNSCSYYKQKITGLE 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	85/310 (27%)
		CAP_ED	604..717	CDD:237999	46/112 (41%)
		CLZ	720..790	CDD:465160	16/82 (20%)
che-6	NP_001343628.1	Ion_trans	68..>245	CDD:459842	56/197 (28%)
		PLN03192	<303..>581	CDD:215625	106/277 (38%)
		CAP_ED	433..544	CDD:237999	45/110 (41%)