Protein Alignment CngA and LOC1279427

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_061511864.1
• Gene: LOC1279427 / 1279427
• VectorBaseID: AGAMI1_006215
• Length: 579
• Species: Anopheles gambiae
• Alignment Length: 657
• Identity: 123/657 - (18%)
• Similarity: 246/657 - (37%)
• Gaps: 162/657 - (24%)

  Fly   135 AEQDEDEEEDDDDVDEDDDDEFGASVCEDNPEEAIARADHDTQQKQHYQPNASDSSYVENGRKLI 199
            :::|:....:..|..||||....|.:                         .|..|:|...|:|.
Mosquito    28 SQRDDSTGFEVSDQLEDDDHVLTARI-------------------------GSRKSFVYRLRRLF 67

  Fly   200 ----QEPSKRSKPSALRRTLQALRQRLTKRNRPKPPDWFLEKFSNTTNTDKIGKGCPAMEDAALS 260
                |.||     |||......|.:|...| :.:...|::
Mosquito    68 LIDRQHPS-----SALHFRSHCLYRRELAR-QVRSDFWYI------------------------- 101

  Fly   261 SEIRGSSVLCNRLSVDPTLQSHYR---WLAIVSLAV---------LYNIIFVVGRAVFWEINKSA 313
                          :.|..|..:.   ||.....||         ..|::...|||
Mosquito   102 --------------IHPFSQFRFYWDVWLIFYFYAVSMLCPFLFSFTNLVRASGRA--------- 143

  Fly   314 PAFWYTLDYLCDFIYLLDTLVHMHEGFLDQGL---LVRDAFRLRRHYFHTKGWYLDVLSMLPTDL 375
                |.:..:.:||..||.::|...|:|:..|   :|....::...|..: ...:|:|.|.|..|
Mosquito   144 ----YMISMVLNFIATLDFVIHACTGYLEDQLNRNVVLHHGKILLKYLKS-DMIVDLLVMAPLTL 203

  Fly   376 AY-IWWPPETCSSLYLPCPVIVR---LNRLLRINRLWEWFD------RTETATGYPNAFRICKVV 430
            :. :::...|.:........||.   :.:::.:..:|.:.:      :.|:...|     |.::|
Mosquito   204 SVGVYYDNATHAISQTVVMDIVHGMMMLKIISLRHVWGYLENVFERYKIESLKYY-----IVRIV 263

  Fly   431 LAILVLIHWNACMYFAISYEIGFSSDSWVYNLNGTRNNTLQRQY-----IYSFYWSTLTLTTIG- 489
            :..::::||..|:|....:|       |.....|...:.::..|     :||..|.....:.|.
Mosquito   264 MTSVLIVHWCICLYKITIFE-------WEAERTGVAISYMEALYQYGVCLYSVSWFMFAYSFIDR 321

  Fly   490 ETPTPENDVEY--LFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVG 552
            |.|:......:  ..:|..::..:.||..|: |:..::|:|:....|..|::   :.|:..:::
Mosquito   322 EIPSDPRAKAFSTACIVIGYMFKLFIFLQII-NLVEIMSSMDRKYAEVTNQL---QTYVRTKQL- 381

  Fly   553 H--ELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEA 615
            |  :::.|::.::|..:... ...|:.::.:|.:.||..|......:.||.|:||......||..
Mosquito   382 HTADMKQRLLYYYAKRYEHC-FFQEDIIMESLSESLKKRITDYSATNFLKTVKIFDGIPNDLLLP 445

  Fly   616 LVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDDGITVLATLGAGSVFGEVSVLEIAGN 680
            ||.::..:::...|.|.:.|..|.:||.:..|.::|. ......:..|..|..|||||:.
Mosquito   446 LVERMTKEIYLQDDLIIKAGSFGDKMYFIIVGMVAVY-THSRKEICHLSDGDNFGEVSMF----- 504

  Fly   681 RTGNRRTANVRSLGYSDLFCL----------AKRDLWETLSDYPEARSTLT----QRGCQLLRKD 731
             |..:|..:|.::.::.::.:          |...:::.|.:....|..:|    ::....|.|.
Mosquito   505 -TRKKRLVSVVAVEFTQVYVIDRMAFKNLFPADHVVYQRLQEMANKRMQITLVFEEQHKNYLLKM 568

  Fly   732 GLLDEQI 738
            |:...:|
Mosquito   569 GMSQNEI 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	52/279 (19%)
		CAP_ED	604..717	CDD:237999	26/122 (21%)
		CLZ	720..790	CDD:465160	5/23 (22%)
LOC1279427	XP_061511864.1	None