Protein Alignment CngA and Elk

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_061508527.1
• Gene: Elk / 1274964
• VectorBaseID: AGAMI1_013860
• Length: 1176
• Species: Anopheles gambiae
• Alignment Length: 681
• Identity: 165/681 - (24%)
• Similarity: 295/681 - (43%)
• Gaps: 126/681 - (18%)

  Fly   212 RRTLQALRQRLTKRNRPKPPDWFLEKFSNTTNTDKIGKGCPAMEDAALSSEIRGSSVLCNRLSVD 276
            ||..:|:..:|:...:|:.....::..||..:                |||..........|...
Mosquito   184 RRRSRAVLYQLSGHYKPEKMKTKIKLNSNLLH----------------SSEAPLPEYKTQALKKS 232

  Fly   277 PTLQSHY-------RWLAI-----VSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYL 329
            ..:.|||       .|:.:     |::||.||..||           .........|.:.:.:::
Mosquito   233 RFILSHYGMFKGCWDWMILVATFYVAIAVPYNAAFV-----------KTDRLTMVSDVVVEALFI 286

  Fly   330 LDTLVHMHEGFLD-QGLLVRDAFRLRRHYFHTKGWY-LDVLSMLPTDLAY---IWWPPETCSSLY 389
            :|.||:....::. :|.:|.|:..:..:|.  :.|: :|:|:.||.|..|   :....|  |.::
Mosquito   287 VDILVNFRTTYVSRKGEVVSDSKSIALNYL--RSWFVVDLLAALPFDHLYASNVISGEE--SHIH 347

  Fly   390 LPCPVIVRLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISYEIGFS 454
            |     |:|.||||:.||.:..||....|    |..:..::|...::.||.||::|.|:.:....
Mosquito   348 L-----VKLTRLLRLARLLQKMDRYSQYT----AMILTLLMLCFSLVAHWLACVWFVIAEKERLM 403

  Fly   455 SDS-----WVYNLN-----GTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDV-EYLFVVADFL 508
            :|:     |::.|.     ...|.|....||.:.|::..:||::|........: |.:|.:...|
Mosquito   404 NDADWDIGWIHTLAERLKIPVSNVTHGEAYITALYFTFTSLTSVGFGNVSATTLSEKIFSIIMML 468

  Fly   509 AGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGAL 573
            .|.|:.|.:.||:.::|..|...|..:|::...:|.::|..::..||:.|:..:|...||.:..:
Mosquito   469 IGALMHAVVFGNVTAIIQRMYSRRSLYQSKWRDLKDFIALHQMPKELKQRMQDYFQTMWSLNHGI 533

  Fly   574 DEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVG 638
            |...:|...|::|:.:|::.:|.:.| |:.||.....|.|:.|.|.:|....:||:|:..|||..
Mosquito   534 DVYEILKEFPEELRGDISMHLHREIL-QLPIFESASQGCLKLLSLHIKANFCAPGEYLIHKGDAL 597

  Fly   639 KEMYIVKRGKLSVVGDDGITVLATLGAGSVFG-EVSVLEIAGNR-----TGNRRT-----ANVRS 692
            ..:|.:..|.:.|:.::  .|:|.||.|.:.| ::|:..:.||:     ||::.|     .:|::
Mosquito   598 SYIYYICNGSMEVMQNN--MVVAILGKGDLVGCDISIHLLHGNQGNSGNTGSQDTIVKSSGDVKA 660

  Fly   693 LGYSDLFCLAKRDLWETLSDYPEARSTLTQRGCQLLRKDGLLDEQIFADSQRVHD---SIEGGIE 754
            |.|.||..:....|.|.|..|||.                   :|.||:..: ||   ::..|.|
Mosquito   661 LTYCDLKSIHMSGLVEVLRLYPEY-------------------QQEFANDIQ-HDLTYNLREGYE 705

  Fly   755 KLE-------------LSVENLNMRLARLLAEYTASQAKIKQRLAKLEMNGGPGTWRLECEPQSR 806
            ..|             :|.::.|...|.     |:|.:.:...|.|...:....:.|......||
Mosquito   706 AEEETENNGPCLALPSISEDDENQSDAE-----TSSASPMNTALQKSPAHNVGSSPRHAKLVHSR 765

  Fly   807 ARSGRLYSLQPKRRPRSRPDATAKSSDAAKQ 837
            .||  |.:|: :|..|.|...||......:|
Mosquito   766 NRS--LVALR-ERVERQRSVQTASQPPTVEQ 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	67/274 (24%)
		CAP_ED	604..717	CDD:237999	39/123 (32%)
		CLZ	720..790	CDD:465160	15/85 (18%)
Elk	XP_061508527.1	None