Protein Alignment CngA and eag

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_061497971.1
• Gene: eag / 1273247
• VectorBaseID: AGAMI1_013308
• Length: 1124
• Species: Anopheles gambiae
• Alignment Length: 766
• Identity: 179/766 - (23%)
• Similarity: 311/766 - (40%)
• Gaps: 143/766 - (18%)

  Fly   166 EEAIARADHDTQQKQH-------YQPNAS------DSSYVENGRKLIQEPSKRSKPSAL----RR 213
            :|.:||.::..:.:||       |:.|.:      ..:.:.|.|.|:          .|    .|
Mosquito    78 KETVARVEYALEHQQHDQFEVLLYKKNKTPLWLLLQVAPIRNERDLV----------VLFLLTFR 132

  Fly   214 TLQALRQRLTKRNRPKPPDWFLEKFSNTTNTDKIGKGCPAMEDAALSSEIRGSSVLCNRLSVDPT 278
            .:.||:|.:...:.......|.:...:.|.:.:.....|.::|....|.      |.:.:|:...
Mosquito   133 DITALKQPIDSEDTKGGLSKFAKLARSVTRSRQFSAHLPTLKDPTKQSN------LAHMMSLSAD 191

  Fly   279 LQSHYR----------------------WLAI-----VSLAVLYNIIFVVGRAVFWEINK-SAPA 315
            :...||                      |:.:     .::.|.||:.|.         || |...
Mosquito   192 VMPQYRQEAPKTPPHILLHYCAFKAIWDWVILCLTFYTAIMVPYNVAFK---------NKTSEDV 247

  Fly   316 FWYTLDYLCDFIYLLDTLVHMHEGFLDQ-GLLVRDAFRLRRHYFHTKGWY-LDVLSMLPTDLAYI 378
            ....:|.:.|.|:.:|.:::.|..|:.. |.:|.|...:|.:|.  |.|: :|:||.||.|:...
Mosquito   248 SLLVVDSIVDVIFFIDIVLNFHTTFVGPGGEVVSDPKVIRMNYL--KSWFIIDLLSCLPYDVFNA 310

  Fly   379 WWPPET-CSSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNAC 442
            :...|. ..||:....|:    ||||:.|:....||   ...|..|..|..:...:|| .||.||
Mosquito   311 FDHDEDGIGSLFSALKVV----RLLRLGRVVRKLDR---YLEYGAAMLILLLCFYMLV-AHWLAC 367

  Fly   443 MYFAISYEIGFSSD------SWVYNL----------------------NGTRNNTLQRQYIYSFY 479
            ::    |.||.|..      ||::.|                      ||....|:   |:.:.|
Mosquito   368 IW----YSIGRSDADNGVQYSWLWKLANVTQSPYSYIWSNESNAPELVNGPSRKTM---YVTALY 425

  Fly   480 WSTLTLTTIG-ETPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVK 543
            ::...:|::| .....|.|.|.:|.:...:...|::|||.|::.::|..|..|..::.:.::.|:
Mosquito   426 FTMTCMTSVGFGNVAAETDNEKVFTICMMIIAALLYATIFGHVTTIIQQMTSATAKYHDMLNNVR 490

  Fly   544 QYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDT 608
            ::|....|...|..||:.:...||:.:..||.::||...|..:||:|.:.::.....:...|...
Mosquito   491 EFMKLHEVPKALSERVMDYVVSTWAMTKGLDTDKVLNYCPKDMKADICVHLNRKVFNEHPAFRLA 555

  Fly   609 EPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDDGITVLATLGAGSVFGEVS 673
            ..|.|.||.:...:...:|||.:...|:....:..:..|.|.|:.||  .|:|.||.|.|||:..
Mosquito   556 SDGCLRALAMHFCMSHSAPGDLLYHTGESIDSLCFIVTGSLEVIQDD--EVVAILGKGDVFGDSF 618

  Fly   674 VLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEARSTLTQRGCQLLRKDGLLDEQI 738
            ..:.|..::    .||||:|.|.||..:.:..|.|.|..|....::..:   .|:....|....|
Mosquito   619 WKDSAVGQS----AANVRALTYCDLHAIKRDKLLEVLDFYQAFANSFAR---NLVLTYNLRHRLI 676

  Fly   739 F---ADSQRVHDSIEGGIEKLEL--SVENL------NMRLARLLAEYTASQ-AKIKQRLAKLEMN 791
            |   ||.:|..:..|....:.:|  |.::|      ..|.|:..|:.|..| ..::..:.|.:.:
Mosquito   677 FRKVADVRREKELAERRKNEPQLGSSQDHLVRKIFSKFRRAQQNAQGTKDQTGSVQSDVEKGDTD 741

  Fly   792 GGPGTW--RLECEPQSRARSGRLYSLQPKRRPRSRPDATAKSSDAAKQNTL 840
            ...|..  :|.....:||.:..:.|..|...|.|.| .:||...|:|...|
Mosquito   742 TDKGKLPAKLTLTEDTRALTTAVPSPSPSPSPSSGP-PSAKGPRASKWGRL 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	73/306 (24%)
		CAP_ED	604..717	CDD:237999	35/112 (31%)
		CLZ	720..790	CDD:465160	17/81 (21%)
eag	XP_061497971.1	None